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Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b.
Sahu A, Rawal N, Pangburn MK. Sahu A, et al. Biochem Pharmacol. 1999 Jun 15;57(12):1439-46. doi: 10.1016/s0006-2952(99)00044-1. Biochem Pharmacol. 1999. PMID: 10353266
Rosmarinic acid has been reported to inhibit complement activation in vivo as well as in vitro. ...Radioiodination of rosmarinic acid was used to demonstrate covalent activation-dependent incorporation of rosmarinic acid specifically into …
Rosmarinic acid has been reported to inhibit complement activation in vivo as well as in vitro. ...Radioiodination of rosma …
Enhanced rosmarinic acid biosynthesis in Solenostemon scutellarioides culture: a precursor-feeding strategy.
Dewanjee S, Gangopadhyay M, Das U, Sahu R, Khanra R. Dewanjee S, et al. Nat Prod Res. 2014;28(20):1691-8. doi: 10.1080/14786419.2014.939973. Epub 2014 Jul 22. Nat Prod Res. 2014. PMID: 25051064
The aim of this study was to employ precursor-feeding strategy for the improved production of rosmarinic acid (RA) in Solenostemon scutellarioides in vitro. The cultures were fed with precursors, namely l-phenylalanine (Phe), l-tyrosine (Tyr) and cucumber juice (CJ) …
The aim of this study was to employ precursor-feeding strategy for the improved production of rosmarinic acid (RA) in Solenost …
Signal transducer and oxidative stress mediated modulation of phenylpropanoid pathway to enhance rosmarinic acid biosynthesis in fungi elicited whole plant culture of Solenostemon scutellarioides.
Dewanjee S, Gangopadhyay M, Das U, Sahu R, Samanta A, Banerjee P. Dewanjee S, et al. Enzyme Microb Technol. 2014 Nov;66:1-9. doi: 10.1016/j.enzmictec.2014.07.006. Epub 2014 Jul 30. Enzyme Microb Technol. 2014. PMID: 25248692
This study aimed to improve rosmarinic acid (RA) production in the whole plant culture of Solenostemon scutellarioides through elicitation with phytopathogenic fungi. ...Therefore, it could be concluded that A. alternata elicited the biosynthesis of rosmarinic …
This study aimed to improve rosmarinic acid (RA) production in the whole plant culture of Solenostemon scutellarioides through …
Development of Simultaneous HPTLC Method and Validation for the Quality Assessment of Ayurvedic Formulation-Ayush Kvatha Churna by Using Marker Compound Rosmarinic Acid, Trans-Cinnamaldehyde and Piperine.
Sahu U, Chauhan NS, Parihar AKS, Karbhal KS, Inchulkar SR, Gupta PK, Singh RK. Sahu U, et al. J Chromatogr Sci. 2024 May 5:bmae019. doi: 10.1093/chromsci/bmae019. Online ahead of print. J Chromatogr Sci. 2024. PMID: 38706309
The Rf value 0.33 for Rosmarinic Acid, 0.69 for Piperine and 0.77 for trans-Cinnamaldehyde was observed and it is exactly complying with the corresponding bands in Ayush Kvatha Churna. The technique has been effectively verified and validated, enabling it to be used …
The Rf value 0.33 for Rosmarinic Acid, 0.69 for Piperine and 0.77 for trans-Cinnamaldehyde was observed and it is exactly comp …
Bioproduction and optimization of rosmarinic acid production in Solenostemon scutellarioides through media manipulation and conservation of high yielding clone via encapsulation.
Sahu R, Dewanjee S, Gangopadhyay M. Sahu R, et al. Nat Prod Commun. 2013 Sep;8(9):1275-8. Nat Prod Commun. 2013. PMID: 24273865
The present study describes the role of different exogenous phytohormones, polyamines and sucrose on growth and rosmarinic acid (RA) production in whole plant culture of Solenostemon scutellarioides. ...
The present study describes the role of different exogenous phytohormones, polyamines and sucrose on growth and rosmarinic acid …
Genomics and Drug Discovery Strategies: The Role of Natural Compounds and Its Receptor in Alzheimer's Disease.
Mishra S, Aziz T, Toppo AJ, Kumar D, Tirkey MP, Beck P, Anjum N, Sharma D, Khan MM, Kumari S, Sahu PR, Nitin M. Mishra S, et al. Cureus. 2024 Jan 17;16(1):e52423. doi: 10.7759/cureus.52423. eCollection 2024 Jan. Cureus. 2024. PMID: 38371064 Free PMC article.
Molecular docking was carried out with screened ligands and target receptors, resulting in the identification of Rosmarinic acid (RA) with CASP8 having docked score (G = -8.0 kcal/mol); Donepezil (FDA drug) dock score (G = -7.3 kcal/mol) (control). ...
Molecular docking was carried out with screened ligands and target receptors, resulting in the identification of Rosmarinic acid …