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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 5
1997 3
1998 3
1999 6
2000 6
2001 5
2002 3
2003 4
2004 3
2005 5
2006 3
2007 5
2008 5
2009 8
2010 7
2011 4
2012 6
2013 8
2014 12
2015 9
2016 6
2017 1
2018 2
2019 6
2020 3
2021 6
2022 6
2023 3
2024 2

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126 results

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Page 1
iNOS as a metabolic enzyme under stress conditions.
Anavi S, Tirosh O. Anavi S, et al. Free Radic Biol Med. 2020 Jan;146:16-35. doi: 10.1016/j.freeradbiomed.2019.10.411. Epub 2019 Oct 28. Free Radic Biol Med. 2020. PMID: 31672462 Review.
NO is synthesized from l-arginine through the action of the nitric oxide synthase (NOS) family of enzymes, which includes three isoforms: endothelial NOS (eNOS), neuronal NOS (nNOS) and inducible NOS (iNOS). iNOS-derived NO has been associated with the pathogenesis …
NO is synthesized from l-arginine through the action of the nitric oxide synthase (NOS) family of enzymes, which includes three isoforms: en …
Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition.
Shah SA, Reagan CE, Bresticker JE, Wolpe AG, Good ME, Macal EH, Billcheck HO, Bradley LA, French BA, Isakson BE, Wolf MJ, Epstein FH. Shah SA, et al. JACC Basic Transl Sci. 2023 Feb 1;8(5):501-514. doi: 10.1016/j.jacbts.2022.11.005. eCollection 2023 May. JACC Basic Transl Sci. 2023. PMID: 37325396 Free PMC article.
Using cardiac magnetic resonance applied to mice fed a high-fat, high-sucrose diet as a model of CMD, we elucidated the role of inducible nitric oxide synthase (iNOS) and 1400W, an iNOS antagonist, in CMD. Global iNOS deletion prevented CMD along with the ass …
Using cardiac magnetic resonance applied to mice fed a high-fat, high-sucrose diet as a model of CMD, we elucidated the role of inducible ni …
Inflammatory mechanisms of pulmonary injury induced by mustards.
Malaviya R, Sunil VR, Venosa A, Vayas KN, Heck DE, Laskin JD, Laskin DL. Malaviya R, et al. Toxicol Lett. 2016 Feb 26;244:2-7. doi: 10.1016/j.toxlet.2015.10.011. Epub 2015 Oct 23. Toxicol Lett. 2016. PMID: 26478570 Free PMC article. Review.
The role of iNOS in cholesterol-induced liver fibrosis.
Anavi S, Eisenberg-Bord M, Hahn-Obercyger M, Genin O, Pines M, Tirosh O. Anavi S, et al. Lab Invest. 2015 Aug;95(8):914-24. doi: 10.1038/labinvest.2015.67. Epub 2015 Jun 22. Lab Invest. 2015. PMID: 26097999 Free article.
The present study investigated the role of inducible nitric oxide synthase (iNOS) in cholesterol-induced liver fibrosis by feeding wild-type (WT) and iNOS-deficient mice with control or high-cholesterol diet (HCD) for 6 weeks. ...The profibrotic role of iNOS …
The present study investigated the role of inducible nitric oxide synthase (iNOS) in cholesterol-induced liver fibrosis by feeding wi …
Effect of chronic intermittent hypoxia (CIH) on neuromuscular junctions and mitochondria in slow- and fast-twitch skeletal muscles of mice-the role of iNOS.
Bannow LI, Bonaterra GA, Bertoune M, Maus S, Schulz R, Weissmann N, Kraut S, Kinscherf R, Hildebrandt W. Bannow LI, et al. Skelet Muscle. 2022 Feb 12;12(1):6. doi: 10.1186/s13395-022-00288-7. Skelet Muscle. 2022. PMID: 35151349 Free PMC article.
Besides wildtype (WT), we included inducible nitric oxide synthase knockout mice (iNOS(-/-)) to evaluate whether iNOS is protective or risk-mediating. ...In the absence of muscular iNOS expression in WT, this damage may arise from extramuscular, e.g., motoneu …
Besides wildtype (WT), we included inducible nitric oxide synthase knockout mice (iNOS(-/-)) to evaluate whether iNOS is prote …
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease.
Maas-Bauer K, Stell AV, Yan KL, de Vega E, Vinnakota JM, Unger S, Núñez N, Norona J, Talvard-Balland N, Koßmann S, Schwan C, Miething C, Martens US, Shoumariyeh K, Nestor RP, Duquesne S, Hanke K, Rackiewicz M, Hu Z, El Khawanky N, Taromi S, Andrlova H, Faraidun H, Walter S, Pfeifer D, Follo M, Waldschmidt J, Melchinger W, Rassner M, Wehr C, Schmitt-Graeff A, Halbach S, Liao J, Häcker G, Brummer T, Dengjel J, Andrieux G, Grosse R, Tugues S, Blazar BR, Becher B, Boerries M, Zeiser R. Maas-Bauer K, et al. Nat Commun. 2024 Jan 10;15(1):446. doi: 10.1038/s41467-024-44703-7. Nat Commun. 2024. PMID: 38199985 Free PMC article.
Mechanistically, ROCK1/2 inhibition or ROCK1 knockdown interfered with CD80, CD86, MHC-II expression and IL-6, IL-1beta, iNOS and TNF production in myeloid cells. This was accompanied by impaired T cell activation by dendritic cells and inhibition of cytoskeletal rearrange …
Mechanistically, ROCK1/2 inhibition or ROCK1 knockdown interfered with CD80, CD86, MHC-II expression and IL-6, IL-1beta, iNOS and TNF …
Arrhythmia and neuronal/endothelial myocyte uncoupling in hyperhomocysteinemia.
Rosenberger D, Moshal KS, Kartha GK, Tyagi N, Sen U, Lominadze D, Maldonado C, Roberts AM, Tyagi SC. Rosenberger D, et al. Arch Physiol Biochem. 2006 Oct-Dec;112(4-5):219-27. doi: 10.1080/13813450601093443. Arch Physiol Biochem. 2006. PMID: 17178594 Free PMC article. Review.
Hcy decreases constitutive neuronal and endothelial nitric oxide (NO), and cardiac diastolic relaxation. Hcy increases the iNOS/NO, peroxynitrite, mitochondrial NADPH oxidase, and suppresses superoxide dismutase (SOD) and redoxins. ...The goal of this review is to elaborat …
Hcy decreases constitutive neuronal and endothelial nitric oxide (NO), and cardiac diastolic relaxation. Hcy increases the iNOS/NO, p …
Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species.
Su J, Chen X, Huang Y, Li W, Li J, Cao K, Cao G, Zhang L, Li F, Roberts AI, Kang H, Yu P, Ren G, Ji W, Wang Y, Shi Y. Su J, et al. Cell Death Differ. 2014 Mar;21(3):388-96. doi: 10.1038/cdd.2013.149. Epub 2013 Oct 25. Cell Death Differ. 2014. PMID: 24162664 Free PMC article.
The characterization of MSCs from different species was by adherence to tissue culture plastic, morphology, specific marker expression, and differentiation potential. On the basis of the inducibility of IDO and iNOS by inflammatory cytokines in MSCs, the tested mammalian s …
The characterization of MSCs from different species was by adherence to tissue culture plastic, morphology, specific marker expression, and …
Antioxidants, oxidative stress, and degenerative neurological disorders.
Floyd RA. Floyd RA. Proc Soc Exp Biol Med. 1999 Dec;222(3):236-45. doi: 10.1046/j.1525-1373.1999.d01-140.x. Proc Soc Exp Biol Med. 1999. PMID: 10601882 Review.
Neurotoxic amounts of RNS are formed by the activity of inducible nitric oxide synthase (iNOS). The demonstration of enhanced 3-nitro-tyrosine formation in affected regions of the Alzheimer's brain, in comparison to age-matched controls, reinforces the importance of neuroi …
Neurotoxic amounts of RNS are formed by the activity of inducible nitric oxide synthase (iNOS). The demonstration of enhanced 3-nitro …
Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions.
Ovechkin AV, Lominadze D, Sedoris KC, Robinson TW, Tyagi SC, Roberts AM. Ovechkin AV, et al. Arch Physiol Biochem. 2007 Feb;113(1):1-12. doi: 10.1080/13813450601118976. Arch Physiol Biochem. 2007. PMID: 17522980 Free PMC article. Review.
Nitric oxide (NO) overproduction via inducible nitric oxide synthase (iNOS) is an important component in the pathogenesis of IR. Reaction of NO with ROS forms RNS as secondary reactive products, which cause platelet activation and upregulation of adhesion molecules. This m …
Nitric oxide (NO) overproduction via inducible nitric oxide synthase (iNOS) is an important component in the pathogenesis of IR. Reac …
126 results