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Hyperleptinaemia in chronic heart failure. Relationships with insulin.
Leyva F, Anker SD, Egerer K, Stevenson JC, Kox WJ, Coats AJ. Leyva F, et al. Eur Heart J. 1998 Oct;19(10):1547-51. doi: 10.1053/euhj.1998.1045. Eur Heart J. 1998. PMID: 9820994
Since leptin secretion is up-regulated by insulin, we also explored whether in congestive heart failure, a hyperinsulinaemic state, plasma leptin levels relate to plasma insulin levels. METHODS: Male patients with weight-stable congestive heart failure (n = 25, aged 55.5 + …
Since leptin secretion is up-regulated by insulin, we also explored whether in congestive heart failure, a hyperinsulinaemic state, plasma l …
Insulin resistance in moderate chronic heart failure is related to hyperleptinaemia, but not to norepinephrine or TNF-alpha.
Doehner W, Rauchhaus M, Godsland IF, Egerer K, Niebauer J, Sharma R, Cicoira M, Florea VG, Coats AJ, Anker SD. Doehner W, et al. Int J Cardiol. 2002 Apr;83(1):73-81. doi: 10.1016/s0167-5273(02)00022-0. Int J Cardiol. 2002. PMID: 11959387
The purpose of this study was to examine in patients with CHF and in comparison to healthy controls subjects whether norepinephrine, TNFalpha or leptin relate to insulin sensitivity. DESIGN: 41 patients with CHF (age 60+/-2 years, NYHA I/II/III/IV 4/12/22/3, peak oxygen co …
The purpose of this study was to examine in patients with CHF and in comparison to healthy controls subjects whether norepinephrine, TNFalph …