[Relationship between T cell subsets and traditional Chinese medicine type in patient with ovarian tumor]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Jun;14(6):334-6, 323.
[Article in Chinese]

Abstract

In order to study the difference in TCM types as well as between Deficiency and Excess type in immunity in the patients with ovarian tumors, the profile of peripheral blood T lymphocyte subsets in 73 cases of ovarian tumors was determined by using flow cytometry and monoclonal antibody technique. The results showed that the total T cells (OKT3) of peripheral blood were almost normal in 73 tumor cases. And 50 of them were malignant tumors in which T helper cell were progressively decreased and T suppressor cell gradually increased in accordance with the order of Qi-Deficiency, Yin-Deficiency, Qi-Yin Deficiency types. The T4/T8 ratio showed significant difference (P < 0.01) compared with the control group and the initial ovarian tumor group. These results indicated that the change in the T lymphocyte subset in tumor was correlated with TCM type and this serves as both clinically sensitive indexes of different TCM type and reflection of the patient's immunologic status.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • CD4-CD8 Ratio
  • Diagnosis, Differential
  • Female
  • Humans
  • Lymphocyte Count
  • Medicine, Chinese Traditional*
  • Middle Aged
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / immunology*
  • T-Lymphocyte Subsets*
  • Yin Deficiency / immunology