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Pan-cancer analysis of NFE2L2 mutations identifies a subset of lung cancers with distinct genomic and improved immunotherapy outcomes.
Wang K, Li Z, Xuan Y, Zhao Y, Deng C, Wang M, Xie C, Yuan F, Pang Q, Mao W, Cai D, Zhong Z, Mei J. Wang K, et al. Cancer Cell Int. 2023 Oct 4;23(1):229. doi: 10.1186/s12935-023-03056-9. Cancer Cell Int. 2023. PMID: 37794491 Free PMC article.
In addition, the in-house WXPH cohort was used to validate the efficacy of immunotherapy in the NFE2L2 mutated patients with NSCLC. RESULTS: In two pan-cancer cohorts, Nrf2-activating mutation was associated with higher TMB value compared to wild-type. We identified a sign …
In addition, the in-house WXPH cohort was used to validate the efficacy of immunotherapy in the NFE2L2 mutated patients with NSCLC. RESULTS: …
SECTM1 is upregulated in immuno-hot tumors and predicts immunotherapeutic efficacy in multiple cancers.
Mei J, Fu Z, Cai Y, Song C, Zhou J, Zhu Y, Mao W, Xu J, Yin Y. Mei J, et al. iScience. 2023 Jan 23;26(2):106027. doi: 10.1016/j.isci.2023.106027. eCollection 2023 Feb 17. iScience. 2023. PMID: 36818292 Free PMC article.
SECTM1 expression was enhanced in tumors from patients with well immunotherapeutic responses in multiple cancers. In addition, SECTM1 was immuno-correlated in pan-cancer and enhanced in immuno-hot tumors. In vitro assays revealed that SECTM1 was upregulated by the IFN-gamm …
SECTM1 expression was enhanced in tumors from patients with well immunotherapeutic responses in multiple cancers. In addition, SECTM1 was im …
Prognostic value and immunological role of PDCD1 gene in pan-cancer.
Miao Y, Wang J, Li Q, Quan W, Wang Y, Li C, Wu J, Mi D. Miao Y, et al. Int Immunopharmacol. 2020 Dec;89(Pt B):107080. doi: 10.1016/j.intimp.2020.107080. Epub 2020 Oct 15. Int Immunopharmacol. 2020. PMID: 33069926
OBJECTIVE: Identify the prognostic value and investigate the association between programmed cell death 1 (PDCD1) gene expression and immune infiltration in pan-cancer. METHODS: We used a series of bioinformatics methods to comprehensively analyze the relationship between P …
OBJECTIVE: Identify the prognostic value and investigate the association between programmed cell death 1 (PDCD1) gene expression and immune …
Visual impairment and blindness caused by retinal diseases: A nationwide register-based study.
Zhou C, Li S, Ye L, Chen C, Liu S, Yang H, Zhuang P, Liu Z, Jiang H, Han J, Jiang Y, Zhou L, Zhou X, Xiao J, Zhang C, Wen L, Lan C, Wang Y, Sun T, Jiang L, Xie P, Chen F, Liang G, Fu D, Zhang T, Shi X, Song Z, Liu X, Li S, Li P, Xu X, Wei Q, Wang W, Huang X, De Z, Deng A, Ding L, Pan X, Wen H, Zhang Z, Lv H, Zhang J, Tian X, Deng Z, Wang H, Wang F, Wang Y, Zhao H, Fang Y, Wu Y, Wu Y, Shen N, Li B, Li X, Dai H, Zhao N, Sun X, Zheng Z, Liu K, Xu X. Zhou C, et al. J Glob Health. 2023 Nov 3;13:04126. doi: 10.7189/jogh.13.04126. J Glob Health. 2023. PMID: 37921040 Free PMC article.
35 results