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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1987 1
1989 1
1990 1
1994 4
1995 1
1996 1
1997 1
1998 2
1999 1
2000 3
2002 4
2003 7
2004 2
2005 11
2006 10
2007 9
2008 18
2009 22
2010 16
2011 11
2012 12
2013 15
2014 18
2015 26
2016 28
2017 40
2018 33
2019 38
2020 42
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2022 66
2023 62
2024 36

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538 results

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Page 1
Multiple rereads of single proteins at single-amino acid resolution using nanopores.
Brinkerhoff H, Kang ASW, Liu J, Aksimentiev A, Dekker C. Brinkerhoff H, et al. Science. 2021 Dec 17;374(6574):1509-1513. doi: 10.1126/science.abl4381. Epub 2021 Nov 4. Science. 2021. PMID: 34735217 Free PMC article.
Here, we demonstrate a nanopore-based single-molecule peptide reader sensitive to single-amino acid substitutions within individual peptides. A DNA-peptide conjugate was pulled through the biological nanopore MspA by the DNA helicase Hel308. ...
Here, we demonstrate a nanopore-based single-molecule peptide reader sensitive to single-amino acid substitutions within individual peptides …
Opto-thermoelectric pulling of light-absorbing particles.
Lin L, Kollipara PS, Kotnala A, Jiang T, Liu Y, Peng X, Korgel BA, Zheng Y. Lin L, et al. Light Sci Appl. 2020 Mar 6;9:34. doi: 10.1038/s41377-020-0271-6. eCollection 2020. Light Sci Appl. 2020. PMID: 32194948 Free PMC article.
It is well known that optical radiation exerts pressure on objects, pushing them along the light path. However, optical pulling of an object against the light path is still a counter-intuitive phenomenon. Herein, we present a general concept of optical pulling-opto- …
It is well known that optical radiation exerts pressure on objects, pushing them along the light path. However, optical pulling of an …
Optical Pulling Forces Enabled by Hyperbolic Metamaterials.
Jin R, Xu Y, Dong ZG, Liu Y. Jin R, et al. Nano Lett. 2021 Dec 22;21(24):10431-10437. doi: 10.1021/acs.nanolett.1c03772. Epub 2021 Dec 13. Nano Lett. 2021. PMID: 34898220
We propose a novel approach to generating optical pulling forces on a gold nanowire, which are placed inside or above a hyperbolic metamaterial and subjected to plane wave illumination. Two mechanisms are found to induce the optical pulling force, including the conc …
We propose a novel approach to generating optical pulling forces on a gold nanowire, which are placed inside or above a hyperbolic me …
Mapping Mechanostable Pulling Geometries of a Therapeutic Anticalin/CTLA-4 Protein Complex.
Liu Z, Moreira RA, Dujmović A, Liu H, Yang B, Poma AB, Nash MA. Liu Z, et al. Nano Lett. 2022 Jan 12;22(1):179-187. doi: 10.1021/acs.nanolett.1c03584. Epub 2021 Dec 17. Nano Lett. 2022. PMID: 34918516 Free PMC article.
We used single-molecule AFM force spectroscopy (AFM-SMFS) in combination with click chemistry to mechanically dissociate anticalin, a non-antibody protein binding scaffold, from its target (CTLA-4), by pulling from eight different anchor residues. We found that pulling …
We used single-molecule AFM force spectroscopy (AFM-SMFS) in combination with click chemistry to mechanically dissociate anticalin, a non-an …
Allosteric Binding-Induced Intramolecular Mechanical-Strain Engineering.
Ma W, Cheng T, Liu FZ, Liu Y, Yan K. Ma W, et al. Angew Chem Int Ed Engl. 2022 Apr 25;61(18):e202202213. doi: 10.1002/anie.202202213. Epub 2022 Mar 9. Angew Chem Int Ed Engl. 2022. PMID: 35212101
Recently, polymer mechanochemistry has attracted much scientific interest due to its potential to develop degradable polymers. When the two ends of a polymer chain experience a linear pulling stress, molecular strain builds up, at sufficiently strong force, a bond scission …
Recently, polymer mechanochemistry has attracted much scientific interest due to its potential to develop degradable polymers. When the two …
Bacterial and archaeal cytoskeletons.
Liu Y, Löwe J. Liu Y, et al. Curr Biol. 2021 May 24;31(10):R542-R546. doi: 10.1016/j.cub.2021.03.011. Curr Biol. 2021. PMID: 34033787 Free article.
A cytoskeleton is a network of intracellular protein filaments that play a structural or mechanical role (such as scaffolding, pushing, or pulling) in the spatiotemporal organization of cellular processes. ...
A cytoskeleton is a network of intracellular protein filaments that play a structural or mechanical role (such as scaffolding, pushing, or …
Generalized Parametric Contrastive Learning.
Cui J, Zhong Z, Tian Z, Liu S, Yu B, Jia J. Cui J, et al. IEEE Trans Pattern Anal Mach Intell. 2023 May 22;PP. doi: 10.1109/TPAMI.2023.3278694. Online ahead of print. IEEE Trans Pattern Anal Mach Intell. 2023. PMID: 37216259
Our analysis demonstrates that GPaCo/PaCo can adaptively enhance the intensity of pushing samples of the same class close as more samples are pulled together with their corresponding centers and benefit hard example learning. ...
Our analysis demonstrates that GPaCo/PaCo can adaptively enhance the intensity of pushing samples of the same class close as more samples ar …
Self-Induced Backaction Optical Pulling Force.
Zhu T, Cao Y, Wang L, Nie Z, Cao T, Sun F, Jiang Z, Nieto-Vesperinas M, Liu Y, Qiu CW, Ding W. Zhu T, et al. Phys Rev Lett. 2018 Mar 23;120(12):123901. doi: 10.1103/PhysRevLett.120.123901. Phys Rev Lett. 2018. PMID: 29694063
We achieve long-range and continuous optical pulling in a periodic photonic crystal background, which supports a unique Bloch mode with the self-collimation effect. Most interestingly, the pulling force reported here is mainly contributed by the intensity gradient f …
We achieve long-range and continuous optical pulling in a periodic photonic crystal background, which supports a unique Bloch mode wi …
The Role of Technology in the Bedside Encounter.
Kumar A, Liu G, Chi J, Kugler J. Kumar A, et al. Med Clin North Am. 2018 May;102(3):443-451. doi: 10.1016/j.mcna.2017.12.006. Med Clin North Am. 2018. PMID: 29650066 Review.
The widespread adoption of electronic medical records in recent years pulls physicians away from time at the bedside. However, when used in conjunction with patients, technology has the potential to bring patients and physicians together. ...
The widespread adoption of electronic medical records in recent years pulls physicians away from time at the bedside. However, when u …
Pulling force and surface tension drive membrane fusion.
Liu X, Tian F, Yue T, Zhang X, Zhong C. Liu X, et al. J Chem Phys. 2017 Nov 21;147(19):194703. doi: 10.1063/1.4997393. J Chem Phys. 2017. PMID: 29166098
In this work, we built a minimal model for membrane fusion, and by using dissipative particle dynamics simulations, we propose a mechanism that the pulling force generated by fusion proteins initiates the fusion process and the membrane tension regulates the subsequent fus …
In this work, we built a minimal model for membrane fusion, and by using dissipative particle dynamics simulations, we propose a mechanism t …
538 results