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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2018 | 1 |
2019 | 1 |
2020 | 1 |
2021 | 2 |
2023 | 1 |
2024 | 1 |
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Page 1
Molecular basis for control of antibiotic production by a bacterial hormone.
Nature. 2021 Feb;590(7846):463-467. doi: 10.1038/s41586-021-03195-x. Epub 2021 Feb 3.
Nature. 2021.
PMID: 33536618
Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis.
Huang C, Zabala D, de Los Santos ELC, Song L, Corre C, Alkhalaf LM, Challis GL.
Huang C, et al.
Nucleic Acids Res. 2023 Feb 22;51(3):1488-1499. doi: 10.1093/nar/gkad009.
Nucleic Acids Res. 2023.
PMID: 36718812
Free PMC article.
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Expanding the Substrate Scope of Nitrating Cytochrome P450 TxtE by Active Site Engineering of a Reductase Fusion.
Saroay R, Roiban GD, Alkhalaf LM, Challis GL.
Saroay R, et al.
Chembiochem. 2021 Jul 1;22(13):2262-2265. doi: 10.1002/cbic.202100145. Epub 2021 May 7.
Chembiochem. 2021.
PMID: 33851500
Free PMC article.
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Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate.
Louka S, Barry SM, Heyes DJ, Mubarak MQE, Ali HS, Alkhalaf LM, Munro AW, Scrutton NS, Challis GL, de Visser SP.
Louka S, et al.
J Am Chem Soc. 2020 Sep 16;142(37):15764-15779. doi: 10.1021/jacs.0c05070. Epub 2020 Sep 2.
J Am Chem Soc. 2020.
PMID: 32811149
Free PMC article.
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Antibiotic Skeletal Diversification via Differential Enoylreductase Recruitment and Module Iteration in trans-Acyltransferase Polyketide Synthases.
Jian X, Pang F, Hobson C, Jenner M, Alkhalaf LM, Challis GL.
Jian X, et al.
J Am Chem Soc. 2024 Mar 6;146(9):6114-6124. doi: 10.1021/jacs.3c13667. Epub 2024 Feb 23.
J Am Chem Soc. 2024.
PMID: 38389455
Free PMC article.
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Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC.
Alkhalaf LM, Barry SM, Rea D, Gallo A, Griffiths D, Lewandowski JR, Fulop V, Challis GL.
Alkhalaf LM, et al.
J Am Chem Soc. 2019 Jan 9;141(1):216-222. doi: 10.1021/jacs.8b08864. Epub 2018 Dec 19.
J Am Chem Soc. 2019.
PMID: 30516965
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