Ten-year persistence of antibody to hepatitis B surface antigen in healthcare workers vaccinated against hepatitis B virus, and response to booster vaccination

Infect Control Hosp Epidemiol. 2003 Oct;24(10):773-6. doi: 10.1086/502132.

Abstract

This study estimated the number of HCWs with protective antibody levels 5 and 10 years after HBV vaccination. Kaplan-Meier probabilities of protective levels were 0.95 at 60 days after vaccination, 0.87 at 5 years, and 0.79 at 10 years. Those without protective levels displayed good response 7 and 30 days after a booster.

MeSH terms

  • Adult
  • Antibodies, Viral / blood*
  • Argentina
  • Female
  • Health Personnel*
  • Hepatitis B Surface Antigens / immunology*
  • Hepatitis B Vaccines / administration & dosage*
  • Humans
  • Immunization, Secondary*
  • Male
  • Middle Aged

Substances

  • Antibodies, Viral
  • Hepatitis B Surface Antigens
  • Hepatitis B Vaccines