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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 2
1980 1
1981 1
1982 4
1983 3
1984 3
1985 3
1987 1
1988 4
1989 2
1990 2
1991 2
1992 5
1993 3
1994 5
1995 5
1996 3
1997 2
1998 4
1999 15
2000 13
2001 10
2002 11
2003 13
2004 27
2005 25
2006 33
2007 32
2008 36
2009 27
2010 33
2011 41
2012 42
2013 40
2014 57
2015 70
2016 58
2017 80
2018 84
2019 95
2020 100
2021 125
2022 112
2023 94
2024 57

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1,240 results

Results by year

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Page 1
Histone methylation: a dynamic mark in health, disease and inheritance.
Greer EL, Shi Y. Greer EL, et al. Nat Rev Genet. 2012 Apr 3;13(5):343-57. doi: 10.1038/nrg3173. Nat Rev Genet. 2012. PMID: 22473383 Free PMC article. Review.
To evaluate how histone methylation contributes to stable or reversible control, we provide a broad overview of how histone methylation is regulated and leads to biological outcomes. ...
To evaluate how histone methylation contributes to stable or reversible control, we provide a broad overview of how histone methylati …
The foundations of immune checkpoint blockade and the ipilimumab approval decennial.
Korman AJ, Garrett-Thomson SC, Lonberg N. Korman AJ, et al. Nat Rev Drug Discov. 2022 Jul;21(7):509-528. doi: 10.1038/s41573-021-00345-8. Epub 2021 Dec 22. Nat Rev Drug Discov. 2022. PMID: 34937915 Review.
However, it is only in the past decade that immunotherapy has made a broad impact on patient survival in multiple high-incidence cancer indications. ...ICB drugs block receptors and ligands involved in pathways that attenuate T cell activation - such as cytotoxic T lymphoc …
However, it is only in the past decade that immunotherapy has made a broad impact on patient survival in multiple high-incidence canc …
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.
Saul D, Khosla S. Saul D, et al. Endocr Rev. 2022 Nov 25;43(6):984-1002. doi: 10.1210/endrev/bnac008. Endocr Rev. 2022. PMID: 35182420 Free PMC article. Review.
While the initial hematoma generates an inflammatory environment in which mesenchymal stem cells and macrophages orchestrate the framework for repair, angiogenesis and cartilage formation mark the second healing period. In the central region, endochondral ossification favo …
While the initial hematoma generates an inflammatory environment in which mesenchymal stem cells and macrophages orchestrate the framework f …
Genetics and mechanisms of thoracic aortic disease.
Chou E, Pirruccello JP, Ellinor PT, Lindsay ME. Chou E, et al. Nat Rev Cardiol. 2023 Mar;20(3):168-180. doi: 10.1038/s41569-022-00763-0. Epub 2022 Sep 21. Nat Rev Cardiol. 2023. PMID: 36131050 Review.
Nitric Oxide Therapy for Diabetic Wound Healing.
Malone-Povolny MJ, Maloney SE, Schoenfisch MH. Malone-Povolny MJ, et al. Adv Healthc Mater. 2019 Jun;8(12):e1801210. doi: 10.1002/adhm.201801210. Epub 2019 Jan 15. Adv Healthc Mater. 2019. PMID: 30645055 Free PMC article. Review.
Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for wound healing; liberating NO from endogenous reservoirs, and supplementing NO from …
Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate inflammation and eradicate bacterial infecti …
Atrial Tachycardia.
Liwanag M, Willoughby C. Liwanag M, et al. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jun 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31194392 Free Books & Documents.
Electrophysiologic features may overlap if there is a small reentrant circuit, as in micro-reentry. It is useful to categorize atrial tachycardia in two broad groups: macroreentrant or focal. The prototypic macroreentrant atrial tachycardia is an atrial flutter. ...
Electrophysiologic features may overlap if there is a small reentrant circuit, as in micro-reentry. It is useful to categorize atrial tachyc …
Review of rifaximin as treatment for SIBO and IBS.
Pimentel M. Pimentel M. Expert Opin Investig Drugs. 2009 Mar;18(3):349-58. doi: 10.1517/13543780902780175. Expert Opin Investig Drugs. 2009. PMID: 19243285 Review.
BACKGROUND: Rifaximin is a broad-range, gastrointestinal-specific antibiotic that demonstrates no clinically relevant bacterial resistance. ...
BACKGROUND: Rifaximin is a broad-range, gastrointestinal-specific antibiotic that demonstrates no clinically relevant bacterial resis …
How I treat pediatric venous thromboembolism in the DOAC era.
Bhat RV, Young G, Sharathkumar AA. Bhat RV, et al. Blood. 2024 Feb 1;143(5):389-403. doi: 10.1182/blood.2022018966. Blood. 2024. PMID: 37390311 Free PMC article.
The direct oral anticoagulants (DOACs) rivaroxaban and dabigatran are newly licensed for the treatment and prevention of venous thromboembolism (VTE) in children and mark a renaissance in pediatric anticoagulation management. They provide a convenient option over standard- …
The direct oral anticoagulants (DOACs) rivaroxaban and dabigatran are newly licensed for the treatment and prevention of venous thromboembol …
Epigenetic Factors of Disease.
Alshiraihi I, Brown MA. Alshiraihi I, et al. Diseases. 2019 Jun 14;7(2):42. doi: 10.3390/diseases7020042. Diseases. 2019. PMID: 31197091 Free PMC article.
These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in patterns of gene expression ultimately dictates cellular consequences. ...Herein, we highlight epi …
These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. …
The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes.
Beacon TH, Delcuve GP, López C, Nardocci G, Kovalchuk I, van Wijnen AJ, Davie JR. Beacon TH, et al. Clin Epigenetics. 2021 Jul 8;13(1):138. doi: 10.1186/s13148-021-01126-1. Clin Epigenetics. 2021. PMID: 34238359 Free PMC article. Review.
Although most studies focus on the H3K4me3 mark, the broad H3K4me3 domain is associated with a plethora of histone modifications (e.g., H3 acetylated at K27) and is therein termed broad epigenetic domain. ...In this review, we present the current knowledge of …
Although most studies focus on the H3K4me3 mark, the broad H3K4me3 domain is associated with a plethora of histone modificatio …
1,240 results