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Did you mean kai xin san (85 results)?
Chinese traditional formula Kaixin San suppressed ferroptosis of hippocampal neurons and cardiomyocytes in mice with paradoxical sleep deprivation.
Cao Y, Li M, Gu L, Zhao X, Zhou A, Miao Y, Wu Y, Ke Z, Hu R, Wang Z, Wu X. Cao Y, et al. J Ethnopharmacol. 2023 Mar 25;304:116034. doi: 10.1016/j.jep.2022.116034. Epub 2022 Dec 15. J Ethnopharmacol. 2023. PMID: 36529245
ETHNOPHARMACOLOGICAL RELEVANCE: Kaixin San (KXS) is one of the most famous traditional Chinese formulas prescribed by Sun Simiao in 652 Christian era. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Kaixin San (KXS) is one of the most famous traditional Chinese formulas prescribed by Sun Simi …
Kaixin-San improves Abeta-induced synaptic plasticity inhibition by affecting the expression of regulation proteins associated with postsynaptic AMPAR expression.
Zhang B, Wang ML, Huang SM, Cui Y, Li Y. Zhang B, et al. Front Pharmacol. 2023 Feb 14;14:1079400. doi: 10.3389/fphar.2023.1079400. eCollection 2023. Front Pharmacol. 2023. PMID: 36865910 Free PMC article.
Objective: To explore the mechanism underlying Kaixin-San (KXS) regulation of postsynaptic AMPA receptor (AMPAR) expression to mitigate toxic effects of the amyloid-beta protein (Abeta). ...
Objective: To explore the mechanism underlying Kaixin-San (KXS) regulation of postsynaptic AMPA receptor (AMPAR) expression to …
[Modified Kaixin San improves memory and synaptic damage of mice with Alzheimer's disease by modulating alphaCaMK-PSD95 protein binding through inhibition of neuroinflammation:a study of mechanism].
Lu ZY, Zhao CY, Yang G, Tong YT, Ba ZT, Reaila A, Yang JM, Xu Y. Lu ZY, et al. Zhongguo Zhong Yao Za Zhi. 2022 Nov;47(22):6217-6226. doi: 10.19540/j.cnki.cjcmm.20220704.501. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 36471948 Chinese.
To investigated the mechanisms underlying the effects of modified Kaixin San(MKXS) on improving memory and synaptic damage of Alzheimer's disease(AD) mouse model with conditional presenilin 1/2 conditional double knockout(PS cDKO). ...
To investigated the mechanisms underlying the effects of modified Kaixin San(MKXS) on improving memory and synaptic damage of …
[Anti-depression targets and mechanism study of Kaixin San].
Yang Z, Zhuo FF, Zhang GM, Sun CH, Tu PF, Yao JC, Zeng KW. Yang Z, et al. Zhongguo Zhong Yao Za Zhi. 2023 Jan;48(2):472-480. doi: 10.19540/j.cnki.cjcmm.20220905.401. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 36725237 Chinese.
This study identified the anti-depression targets of Kaixin San(KXS) in the brain tissue with "target fishing" strategy, and explored the target-associated pharmacological signaling pathways to reveal the anti-depression molecular mechanism of KXS. …
This study identified the anti-depression targets of Kaixin San(KXS) in the brain tissue with "target fishing&quo …
Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation.
Xu M, Zhai W, Zhang Y, Pan J, Li J, Huang S. Xu M, et al. BMC Complement Med Ther. 2023 May 12;23(1):156. doi: 10.1186/s12906-023-03970-5. BMC Complement Med Ther. 2023. PMID: 37173696 Free PMC article.
BACKGROUND: Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-ni-san, is a highly effective formula with demonstrated efficacy in preventing depression in previous studies. ...
BACKGROUND: Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-ni-san, is a highly effective formula …
Rapid discovery of quality-markers from Kaixin San using chinmedomics analysis approach.
Wang XJ, Zhang AH, Kong L, Yu JB, Gao HL, Liu ZD, Sun H. Wang XJ, et al. Phytomedicine. 2019 Feb 15;54:371-381. doi: 10.1016/j.phymed.2017.12.014. Epub 2017 Dec 18. Phytomedicine. 2019. PMID: 30322673
BACKGROUND: Alzheimer's disease (AD), a progressive neurodegenerative disease, is more common disease of dementia among the elderly by multiple factors and presents enormous challenges in terms of diagnosis and treatment. Kaixin San (KXS), is a classic prescription …
BACKGROUND: Alzheimer's disease (AD), a progressive neurodegenerative disease, is more common disease of dementia among the elderly by multi …
[UHPLC-Q-Exactive Orbitrap MS/MS-based rapid identification of chemical components in substance benchmark of Kaixin San].
Li HR, Dong PP, Li HJ, Xu J, Wang H, Cui YF, Sun ZQ, Gao P, Zhang JY. Li HR, et al. Zhongguo Zhong Yao Za Zhi. 2022 Feb;47(4):938-950. doi: 10.19540/j.cnki.cjcmm.20210823.304. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 35285193 Chinese.
The scanning was performed in the negative ion mode. The complex component groups in Kaixin San substance benchmark were quickly and accurately identified and clearly assigned based on the comparison of the retention time and MS data with those of the reference subs …
The scanning was performed in the negative ion mode. The complex component groups in Kaixin San substance benchmark were quick …
Strategy for the multi-component characterization and quality evaluation of volatile organic components in Kaixin San by correlating the analysis by headspace gas chromatography/ion mobility spectrometry and headspace gas chromatography/mass spectrometry.
Yin J, Lin R, Wu M, Ding H, Han L, Yang W, Song X, Li W, Qu H, Yu H, Li Z. Yin J, et al. Rapid Commun Mass Spectrom. 2021 Nov 15;35(21):e9174. doi: 10.1002/rcm.9174. Rapid Commun Mass Spectrom. 2021. PMID: 34350664
RATIONALE: Kaixin San (KXS) is a prescription traditional Chinese medicine (TCM) with the effects of "tonifying the kidney and brain" and "improving memory". ...
RATIONALE: Kaixin San (KXS) is a prescription traditional Chinese medicine (TCM) with the effects of "tonifying the kidney and …
Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats.
Li X, Wen W, Li P, Fu Y, Chen H, Wang F, Dai Y, Xu S. Li X, et al. Oxid Med Cell Longev. 2021 Jul 9;2021:5590745. doi: 10.1155/2021/5590745. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34306310 Free PMC article.
Mitochondrial dysfunctions and glutamate neurotoxicity due to chronic hypoperfusion and oxidative stress were regarded as the major risk factors in the pathogenesis. Kaixin San (KXS), a classic prescription of Beiji Qianjin Yaofang, was applied to treatment for "amn …
Mitochondrial dysfunctions and glutamate neurotoxicity due to chronic hypoperfusion and oxidative stress were regarded as the major risk fac …
[Effect of six class of Kaixin San formulas on pharmacological and preliminary mechanism of Alzheimer's disease mice].
Li MH, Zhang J, Zhao RQ, Dong XZ, Hu Y, Chen T, Li J, Liu L, Liu P. Li MH, et al. Zhongguo Zhong Yao Za Zhi. 2016 Apr;41(7):1269-1274. doi: 10.4268/cjcmm20160718. Zhongguo Zhong Yao Za Zhi. 2016. PMID: 28879742 Chinese.
Part dose of Kaixin San of Yixin Fang, Kaixin Wan of Yimen Fang, Dingzhi Xiaowan of Beji Qianjin Yaofang and Dingzhi Wan of Guji Luyan could improve the learning and memory ability evaluation indicators, significantly increased BDNF and Ach in the hippocampus …
Part dose of Kaixin San of Yixin Fang, Kaixin Wan of Yimen Fang, Dingzhi Xiaowan of Beji Qianjin Yaofang and Dingzhi Wa …
18 results