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2021 | 2 |
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Copper(I)-Catalyzed Nitrile-Addition/N-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6H-indolo[3,2-c]quinolin-6-ones as Potent Topoisomerase-I Inhibitors.
J Med Chem. 2021 Feb 11;64(3):1435-1453. doi: 10.1021/acs.jmedchem.0c00727. Epub 2021 Jan 25.
J Med Chem. 2021.
PMID: 33492141
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function.
Lee HW, Chen SJ, Tsai KJ, Hsu KS, Chen YF, Chang CH, Lin HH, Hsueh WY, Hsieh HP, Lee YF, Chiang HC, Chang JY.
Lee HW, et al. Among authors: hsueh wy.
J Biomed Sci. 2024 May 9;31(1):46. doi: 10.1186/s12929-024-01037-2.
J Biomed Sci. 2024.
PMID: 38725007
Free PMC article.
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Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-RafV600E and potent EGFR/VEGFR2 inhibitory 4-(3-hydroxyanilino)-6-(1H-1,2,3-triazol-4-yl)quinazolines.
Lee CI, Liao CB, Chen CS, Cheng FY, Chung YH, Wang YC, Ciou SY, Hsueh WY, Lo TH, Huang GR, Huang HY, Tsai CS, Lu YJ, Chuang SH, Huang JJ.
Lee CI, et al. Among authors: hsueh wy.
Bioorg Chem. 2021 Apr;109:104715. doi: 10.1016/j.bioorg.2021.104715. Epub 2021 Feb 8.
Bioorg Chem. 2021.
PMID: 33647741
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Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.
Chuang SH, Lee YE, Huang LYL, Chen CK, Lai CL, Lin YH, Yang JY, Yang SC, Chang LH, Chen CH, Liu CW, Lin HS, Lee YR, Huang KP, Fu KC, Jen HM, Lai JY, Jian PS, Wang YC, Hsueh WY, Tsai PY, Hong WH, Chang CC, Wu DZ, Wu J, Chen MH, Yu KM, Chern CY, Chang JM, Lau JYN, Huang JJ.
Chuang SH, et al. Among authors: hsueh wy.
Eur J Med Chem. 2020 Apr 1;191:112118. doi: 10.1016/j.ejmech.2020.112118. Epub 2020 Feb 7.
Eur J Med Chem. 2020.
PMID: 32113126
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