hongwen du - Search Results

Year	Number of Results
2009	1
2016	1
2019	1
2020	2
2021	2
2022	2
2023	2
2024	2

1

Optimization of a Novel Mandelamide-Derived Pyrrolopyrimidine Series of PERK Inhibitors.

Stokes ME, Surman MD, Calvo V, Surguladze D, Li AH, Gasparek J, Betzenhauser M, Zhu G, Du H, Rigby AC, Mulvihill MJ. Stokes ME, et al. Among authors: du h. Pharmaceutics. 2022 Oct 19;14(10):2233. doi: 10.3390/pharmaceutics14102233. Pharmaceutics. 2022. PMID: 36297668 Free PMC article.

2

Aminopeptidase MNP-1 triggers intestine protease production by activating daf-16 nuclear location to degrade pore-forming toxins in Caenorhabditis elegans.

Chen F, Pang C, Zheng Z, Zhou W, Guo Z, Xiao D, Du H, Bravo A, Soberón M, Sun M, Peng D. Chen F, et al. Among authors: du h. PLoS Pathog. 2023 Jul 13;19(7):e1011507. doi: 10.1371/journal.ppat.1011507. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37440595 Free PMC article.

3

Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors.

Calvo V, Surguladze D, Li AH, Surman MD, Malibhatla S, Bandaru M, Jonnalagadda SK, Adarasandi R, Velmala M, Singireddi DRP, Velpuri M, Nareddy BR, Sastry V, Mandati C, Guguloth R, Siddiqui S, Patil BS, Chad E, Wolfley J, Gasparek J, Feldman K, Betzenhauser M, Wiens B, Koszelak-Rosenblum M, Zhu G, Du H, Rigby AC, Mulvihill MJ. Calvo V, et al. Among authors: du h. Bioorg Med Chem Lett. 2021 Jul 1;43:128058. doi: 10.1016/j.bmcl.2021.128058. Epub 2021 Apr 23. Bioorg Med Chem Lett. 2021. PMID: 33895276 Free article.

4

Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator.

Thomson CG, Aicher TD, Cheng W, Du H, Dudgeon C, Li AH, Li B, Lightcap E, Luo D, Mulvihill M, Pan P, Rahemtulla BF, Rigby AC, Sherborne B, Sood S, Surguladze D, Talbot EPA, Tameire F, Taylor S, Wang Y, Wojnarowicz P, Xiao F, Ramurthy S. Thomson CG, et al. Among authors: du h. J Med Chem. 2024 Apr 11;67(7):5259-5271. doi: 10.1021/acs.jmedchem.3c02384. Epub 2024 Mar 26. J Med Chem. 2024. PMID: 38530741

5

Evaluation of an Ussing Chamber System Equipped with Rat Intestinal Tissues to Predict Intestinal Absorption and Metabolism in Humans.

Guan C, Yang Y, Tian D, Jiang Z, Zhang H, Li Y, Yan J, Zhang C, Chen C, Zhang J, Wang J, Wang Y, Du H, Zhou H, Wang T. Guan C, et al. Among authors: du h. Eur J Drug Metab Pharmacokinet. 2022 Sep;47(5):639-652. doi: 10.1007/s13318-022-00780-x. Epub 2022 Jun 22. Eur J Drug Metab Pharmacokinet. 2022. PMID: 35733077

6

Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.

Wang S, Chen C, Guan C, Qiu L, Zhang L, Zhang S, Zhou H, Du H, Li C, Wu Y, Chang H, Wang T. Wang S, et al. Among authors: du h. Pharmacol Res Perspect. 2021 Oct;9(5):e00879. doi: 10.1002/prp2.879. Pharmacol Res Perspect. 2021. PMID: 34628723 Free PMC article.

7

Bacillus thuringiensis targets the host intestinal epithelial junctions for successful infection of Caenorhabditis elegans.

Wan L, Lin J, Du H, Zhang Y, Bravo A, Soberón M, Sun M, Peng D. Wan L, et al. Among authors: du h. Environ Microbiol. 2019 Mar;21(3):1086-1098. doi: 10.1111/1462-2920.14528. Epub 2019 Feb 14. Environ Microbiol. 2019. PMID: 30637902

8

The value of diffusion-weighted imaging in assessing the ADC changes of tissues adjacent to breast carcinoma.

Yili Z, Xiaoyan H, Hongwen D, Yun Z, Xin C, Peng W, Youmin G. Yili Z, et al. Among authors: hongwen d. BMC Cancer. 2009 Jan 14;9:18. doi: 10.1186/1471-2407-9-18. BMC Cancer. 2009. PMID: 19144163 Free PMC article.

9

Comparison of Ussing Chamber and Caco-2 Model in Evaluation of Intestinal Absorption Mechanism of Compounds from Different BCS Classifications.

Tian D, Yang Y, Zhang H, Du H, Zhou H, Wang T. Tian D, et al. Among authors: du h. Drug Metab Bioanal Lett. 2023;16(2):105-112. doi: 10.2174/2949681016666230913105920. Drug Metab Bioanal Lett. 2023. PMID: 37711012

10

Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain Barrier.

Colclough N, Alluri RV, Tucker JW, Gozalpour E, Li D, Du H, Li W, Harlfinger S, O'Neill DJ, Sproat GG, Chen K, Yan Y, McGinnity DF. Colclough N, et al. Among authors: du h. Drug Metab Dispos. 2024 Jan 9;52(2):95-105. doi: 10.1124/dmd.123.001476. Drug Metab Dispos. 2024. PMID: 38071533

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