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162 results

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Page 1
Mesenchymal stem/stromal cells in cancer therapy.
Lan T, Luo M, Wei X. Lan T, et al. J Hematol Oncol. 2021 Nov 17;14(1):195. doi: 10.1186/s13045-021-01208-w. J Hematol Oncol. 2021. PMID: 34789315 Free PMC article. Review.
Moreover, armed with the immunomodulation capacity and tumor-homing property, MSCs are of special relevance for cell-based therapies in the treatment of cancer. ...
Moreover, armed with the immunomodulation capacity and tumor-homing property, MSCs are of special relevance for cell-based therapies …
A Brief Overview of Global Trends in MSC-Based Cell Therapy.
Jovic D, Yu Y, Wang D, Wang K, Li H, Xu F, Liu C, Liu J, Luo Y. Jovic D, et al. Stem Cell Rev Rep. 2022 Jun;18(5):1525-1545. doi: 10.1007/s12015-022-10369-1. Epub 2022 Mar 28. Stem Cell Rev Rep. 2022. PMID: 35344199 Free PMC article. Review.
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or medicinal signaling cells, are important adult stem cells for regenerative medicine, largely due to their regenerative characteristics such as self-renewal, secretion of trophic factors, and the capab …
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or medicinal signaling cells, are important adult stem cells fo …
Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment.
Wu Y, Wan S, Yang S, Hu H, Zhang C, Lai J, Zhou J, Chen W, Tang X, Luo J, Zhou X, Yu L, Wang L, Wu A, Fan Q, Wu J. Wu Y, et al. J Nanobiotechnology. 2022 Dec 27;20(1):542. doi: 10.1186/s12951-022-01746-6. J Nanobiotechnology. 2022. PMID: 36575429 Free PMC article. Review.
In this review, we have summarized the advances in the fabrication, characterization and homing capacity of macrophage membrane cloaking nanoparticles in various diseases, including cancers, immune diseases, cardiovascular diseases, central nervous system diseases, and mic …
In this review, we have summarized the advances in the fabrication, characterization and homing capacity of macrophage membrane cloak …
Chemokines and lymphocyte homing in Sjogren's syndrome.
Liao J, Yu X, Huang Z, He Q, Yang J, Zhang Y, Chen J, Song W, Luo J, Tao Q. Liao J, et al. Front Immunol. 2024 Apr 26;15:1345381. doi: 10.3389/fimmu.2024.1345381. eCollection 2024. Front Immunol. 2024. PMID: 38736890 Free PMC article. Review.
A variety of molecules have been shown to be involved in lymphocyte homing, including tumor necrosis factor-alpha, interferon (IFN)-alpha, IFN-beta, and B cell activating factor. ...The aim of this study was to explore the relationship between lymphocyte homing and …
A variety of molecules have been shown to be involved in lymphocyte homing, including tumor necrosis factor-alpha, interferon (IFN)-a …
Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications.
Wang Y, Zhang K, Li T, Maruf A, Qin X, Luo L, Zhong Y, Qiu J, McGinty S, Pontrelli G, Liao X, Wu W, Wang G. Wang Y, et al. Theranostics. 2021 Jan 1;11(1):164-180. doi: 10.7150/thno.47841. eCollection 2021. Theranostics. 2021. PMID: 33391468 Free PMC article.
In this work, we aimed to develop an ideal biomimetic nanoparticle for targeted AS therapy. Methods: Based on macrophage "homing" into atherosclerotic lesions and cell membrane coating nanotechnology, biomimetic nanoparticles (MM/RAPNPs) were fabricated with a macrophage m …
In this work, we aimed to develop an ideal biomimetic nanoparticle for targeted AS therapy. Methods: Based on macrophage "homing" int …
Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism.
Ling L, Feng X, Wei T, Wang Y, Wang Y, Wang Z, Tang D, Luo Y, Xiong Z. Ling L, et al. Stem Cell Res Ther. 2019 Jan 25;10(1):46. doi: 10.1186/s13287-019-1136-x. Stem Cell Res Ther. 2019. PMID: 30683144 Free PMC article.
After hAD-MSC transplantation or hAD-MSC-CM injection, serum sex hormone levels, estrous cycles, ovarian pathological changes, follicle counts, granulosa cell (GC) apoptosis, and Bcl-2, Bax, and VEGF expression in ovaries were examined. RESULTS: PKH26-labeled hAD-MSCs mainly h …
After hAD-MSC transplantation or hAD-MSC-CM injection, serum sex hormone levels, estrous cycles, ovarian pathological changes, follicle coun …
Pericardial Delivery of SDF-1α Puerarin Hydrogel Promotes Heart Repair and Electrical Coupling.
Luo L, Li Y, Bao Z, Zhu D, Chen G, Li W, Xiao Y, Wang Z, Zhang Y, Liu H, Chen Y, Liao Y, Cheng K, Li Z. Luo L, et al. Adv Mater. 2024 Jan;36(1):e2302686. doi: 10.1002/adma.202302686. Epub 2023 Sep 15. Adv Mater. 2024. PMID: 37665792
In this work, SDF-1alpha-encapsulated Puerarin (PUE) hydrogel (SDF-1alpha@PUE) is capable of enhancing endogenous stem cell homing and simultaneously polarizing the recruited monocyte/macrophages into a repairing phenotype. ...
In this work, SDF-1alpha-encapsulated Puerarin (PUE) hydrogel (SDF-1alpha@PUE) is capable of enhancing endogenous stem cell homing an …
Directional homing of glycosylation-modified bone marrow mesenchymal stem cells for bone defect repair.
Chen L, Luo W, Wang Y, Song X, Li S, Wu J, Sun L. Chen L, et al. J Nanobiotechnology. 2021 Jul 31;19(1):228. doi: 10.1186/s12951-021-00969-3. J Nanobiotechnology. 2021. PMID: 34332597 Free PMC article.
Here we explore the effect of fucosylation modification on the directional homing of bone marrow mesenchymal stem cells (BMSCs) and their ability to repair bone defects. ...CONCLUSIONS: The glycosylation modification of BMSCs has significantly enhanced their directional …
Here we explore the effect of fucosylation modification on the directional homing of bone marrow mesenchymal stem cells (BMSCs) and t …
An Acellular Scaffold Facilitates Endometrial Regeneration and Fertility Restoration via Recruiting Endogenous Mesenchymal Stem Cells.
Xin L, Zheng X, Chen J, Hu S, Luo Y, Ge Q, Jin X, Ma L, Zhang S. Xin L, et al. Adv Healthc Mater. 2022 Nov;11(21):e2201680. doi: 10.1002/adhm.202201680. Epub 2022 Sep 9. Adv Healthc Mater. 2022. PMID: 36049781
Mechanistically, the CES implantation promotes endogenous MSCs recruitment via a macrophage-coordinated strategy; then the homing MSCs exert the function of immunomodulation and altered local microenvironments toward regeneration. ...
Mechanistically, the CES implantation promotes endogenous MSCs recruitment via a macrophage-coordinated strategy; then the homing MSC …
Platelet-Derived Microparticles Mediate the Intra-Articular Homing of Mesenchymal Stem Cells in Early-Stage Cartilage Lesions.
Liang C, Huang J, Luo P, Wang Z, He J, Wu S, Peng C, Cao X. Liang C, et al. Stem Cells Dev. 2020 Apr 1;29(7):414-424. doi: 10.1089/scd.2019.0137. Epub 2020 Mar 12. Stem Cells Dev. 2020. PMID: 32000580
In this study, the optimal homing time of SMSCs was determined by evaluating the SMSC homing efficiency at 1, 3, 7, 14, and 28 days after injury using a rat cartilage defect model. ...SMSCs had an optimal homing efficiency in the very early stage (1 day) afte …
In this study, the optimal homing time of SMSCs was determined by evaluating the SMSC homing efficiency at 1, 3, 7, 14, and 28 …
162 results