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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.
Shay JW, Homma N, Zhou R, Naseer MI, Chaudhary AG, Al-Qahtani M, Hirokawa N, Goudarzi M, Fornace AJ Jr, Baeesa S, Hussain D, Bangash M, Alghamdi F, Schulten HJ, Carracedo A, Khan I, Qashqari H, Madkhali N, Saka M, Saini KS, Jamal A, Al-Maghrabi J, Abuzenadah A, Chaudhary A, Al Qahtani M, Damanhouri G, Alkhatabi H, Goodeve A, Crookes L, Niksic N, Beauchamp N, Abuzenadah AM, Vaught J, Budowle B, Assidi M, Buhmeida A, Al-Maghrabi J, Buhmeida A, Assidi M, Merdad L, Kumar S, Miura S, Gomez K, Carracedo A, Rasool M, Rebai A, Karim S, Eldin HFN, Abusamra H, Alhathli EM, Salem N, Al-Qahtani MH, Kumar S, Faheem H, Agarwa A, Nieschlag E, Wistuba J, Damm OS, Beg MA, Abdel-Meguid TA, Mosli HA, Bajouh OS, Abuzenadah AM, Al-Qahtani MH, Coskun S, Abu-Elmagd M, Buhmeida A, Dallol A, Al-Maghrabi J, Hakamy S, Al-Qahtani W, Al-Harbi A, Hussain S, Assidi M, Al-Qahtani M, Abuzenadah A, Ozkosem B, DuBois R, Messaoudi SS, Dandana MT, Mahjoub T, Almawi WY, Abdalla S, Al-Aama MN, Elzawahry A, Takahashi T, Mimaki S, Furukawa E, Nakatsuka R, Kurosaka I, Nishigaki T, Nakamura H, Serada S, Naka T, Hirota S, Shibata T, Tsuchihara K, Nishida T, Kato M, Mehmood S, Ashraf NM, Asif A, Bilal M, Mehmood MS, Hussain … See abstract for full author list ➔ Shay JW, et al. BMC Genomics. 2016 Jul 20;17 Suppl 6(Suppl 6):487. doi: 10.1186/s12864-016-2858-0. BMC Genomics. 2016. PMID: 27454254 Free PMC article.
Al-Halbosiy, Rghad Kadhim Al lihabi, Basim Mohammed Khashman P20 Etanercept, a TNF-alpha inhibitor, alleviates mechanical hypersensitivity and spontaneous pain in a rat model of chemotherapy-induced neuropathic pain Djouhri, Laiche, Chaudhary Adeel, Nedjadi, Taoufik P21 Sleeping …
Al-Halbosiy, Rghad Kadhim Al lihabi, Basim Mohammed Khashman P20 Etanercept, a TNF-alpha inhibitor, alleviates mechanical hypersensitivity a …
The killer of Socrates: Coniine and Related Alkaloids in the Plant Kingdom.
Hotti H, Rischer H. Hotti H, et al. Molecules. 2017 Nov 14;22(11):1962. doi: 10.3390/molecules22111962. Molecules. 2017. PMID: 29135964 Free PMC article. Review.
A transamination reaction incorporates nitrogen from l-alanine and non-enzymatic cyclization leads to gamma-coniceine, the first hemlock alkaloid in the pathway. Ultimately, reduction of gamma-coniceine to coniine is facilitated by NADPH-dependent gamma-conic …
A transamination reaction incorporates nitrogen from l-alanine and non-enzymatic cyclization leads to gamma-coniceine, the first heml …
The PPAR-gamma agonist rosiglitazone facilitates Akt rephosphorylation and inhibits apoptosis in cardiomyocytes during hypoxia/reoxygenation.
Kilter H, Werner M, Roggia C, Reil JC, Schäfers HJ, Kintscher U, Böhm M. Kilter H, et al. Diabetes Obes Metab. 2009 Nov;11(11):1060-7. doi: 10.1111/j.1463-1326.2009.01097.x. Epub 2009 Sep 3. Diabetes Obes Metab. 2009. PMID: 19732122
BACKGROUND AND AIM: Results on the cardiovascular effects of PPAR-gamma agonists are conflicting. On one hand, it was suggested that the PPAR-gamma agonist rosiglitazone may increase the risk of cardiovascular events. On the other hand, PPAR-gamma agonists re …
BACKGROUND AND AIM: Results on the cardiovascular effects of PPAR-gamma agonists are conflicting. On one hand, it was suggested that …
De novo transcriptome assembly of Conium maculatum L. to identify candidate genes for coniine biosynthesis.
Peddinti G, Hotti H, Teeri TH, Rischer H. Peddinti G, et al. Sci Rep. 2022 Oct 20;12(1):17562. doi: 10.1038/s41598-022-21728-w. Sci Rep. 2022. PMID: 36266299 Free PMC article.
The current study focuses on describing the coniine pathway by identifying in silico transcript candidates for polyketide reductase, L-alanine:5-keto-octanal aminotransferase, gamma-coniceine reductase, and S-adenosyl-L-methionine:coniine methyltransferase. ...
The current study focuses on describing the coniine pathway by identifying in silico transcript candidates for polyketide reductase, L-alani …
Facile Isolation of LCC-Fraction from Organosolv Lignin by Simple Soxhlet Extraction.
Ebrahimi Majdar R, Ghasemian A, Resalati H, Saraeian A, Crestini C, Lange H. Ebrahimi Majdar R, et al. Polymers (Basel). 2019 Jan 31;11(2):225. doi: 10.3390/polym11020225. Polymers (Basel). 2019. PMID: 30960209 Free PMC article.
This LCC fraction was found to contain exclusively phenyl glycosides and gamma-esters as LCC motifs....
This LCC fraction was found to contain exclusively phenyl glycosides and gamma-esters as LCC motifs....
Peripheral expansion of circulating T-helper 1 cells predicts coronary endothelial dysfunction after cardiac transplantation.
Methe H, Wiegand D, Welsch U, Krombach F, Meiser B, Nabauer M, Koglin J. Methe H, et al. J Heart Lung Transplant. 2005 Jul;24(7):833-40. doi: 10.1016/j.healun.2004.05.014. J Heart Lung Transplant. 2005. PMID: 15982610
In these patients, mRNA transcript levels for the T-helper (Th)1 signature cytokines interferon (INF)-gamma (p<0.0001) and interleukin (IL)-2 (p<0.005) and STAT4 (Th1 transcription factor, p<0,05) were significantly higher than in the remaining 24 patients with no …
In these patients, mRNA transcript levels for the T-helper (Th)1 signature cytokines interferon (INF)-gamma (p<0.0001) and interle …
Developmental programming: reproductive endocrinopathies in the adult female sheep after prenatal testosterone treatment are reflected in altered ontogeny of GnRH afferents.
Jansen HT, Hershey J, Mytinger A, Foster DL, Padmanabhan V. Jansen HT, et al. Endocrinology. 2011 Nov;152(11):4288-97. doi: 10.1210/en.2011-0117. Epub 2011 Sep 20. Endocrinology. 2011. PMID: 21933866 Free PMC article.
Tissue was analyzed for GnRH immunoreactivity (ir), total GnRH afferents (Synapsin-I ir), glutamate [vesicular glutamate transporter-2 (VGLUT2)-ir], and gamma-aminobutyric acid [GABA, vesicular GABA transporter (VGAT)-ir] afferents and glial associations (glial fibrillary …
Tissue was analyzed for GnRH immunoreactivity (ir), total GnRH afferents (Synapsin-I ir), glutamate [vesicular glutamate transporter-2 (VGLU …
Analysing covariates with spike at zero: a modified FP procedure and conceptual issues.
Becher H, Lorenz E, Royston P, Sauerbrei W. Becher H, et al. Biom J. 2012 Sep;54(5):686-700. doi: 10.1002/bimj.201100263. Epub 2012 Jul 9. Biom J. 2012. PMID: 22778015
Here, we systematically derive the theoretical shapes of dose-response curves under given distributional assumptions (normal, log normal, gamma) in the framework of a logistic regression model. Further, we check the performance of the procedure in a simulation study and co …
Here, we systematically derive the theoretical shapes of dose-response curves under given distributional assumptions (normal, log normal, …
Ultrahigh-resolution study on Pyrococcus abyssi rubredoxin: II. Introduction of an O-H...Sgamma-Fe hydrogen bond increased the reduction potential by 65 mV.
Bönisch H, Schmidt CL, Bianco P, Ladenstein R. Bönisch H, et al. J Biol Inorg Chem. 2007 Nov;12(8):1163-71. doi: 10.1007/s00775-007-0289-8. Epub 2007 Aug 22. J Biol Inorg Chem. 2007. PMID: 17712580
The effect of D-H...S(gamma)-Fe hydrogen bonding on the reduction potential of rubredoxin was investigated by the introduction of an O-H...S(gamma)-Fe hydrogen bond on the surface of Pyrococcus abyssi rubredoxin. The formation of a weak hydrogen bond between Ser44-O …
The effect of D-H...S(gamma)-Fe hydrogen bonding on the reduction potential of rubredoxin was investigated by the introduction of an …
Seasonal plasticity within the gonadotropin-releasing hormone (GnRH) system of the ewe: changes in identified GnRH inputs and glial association.
Jansen HT, Cutter C, Hardy S, Lehman MN, Goodman RL. Jansen HT, et al. Endocrinology. 2003 Aug;144(8):3663-76. doi: 10.1210/en.2002-0188. Endocrinology. 2003. PMID: 12865349
We therefore examined GnRH neurons of breeding season (BS) and nonbreeding season (anestrus) ewes and tested the hypotheses that specific (i.e. gamma-aminobutyric acid, catecholamine, neuropeptide Y, or beta-endorphin) inputs to GnRH neurons change seasonally, and concomit …
We therefore examined GnRH neurons of breeding season (BS) and nonbreeding season (anestrus) ewes and tested the hypotheses that specific (i …
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