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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 2
1992 2
1993 1
1994 2
1996 3
1998 1
2000 1
2002 8
2003 5
2004 1
2005 24
2006 12
2007 14
2008 14
2009 18
2010 10
2011 13
2012 17
2013 34
2014 38
2015 46
2016 46
2017 63
2018 74
2019 69
2020 118
2021 147
2022 180
2023 208
2024 107

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1,154 results

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Page 1
Heterogeneity within molecular subtypes of breast cancer.
Turner KM, Yeo SK, Holm TM, Shaughnessy E, Guan JL. Turner KM, et al. Am J Physiol Cell Physiol. 2021 Aug 1;321(2):C343-C354. doi: 10.1152/ajpcell.00109.2021. Epub 2021 Jun 30. Am J Physiol Cell Physiol. 2021. PMID: 34191627 Free PMC article. Review.
Breast cancer is the quintessential example of how molecular characterization of tumor biology guides therapeutic decisions. From the discovery of the estrogen receptor to current clinical molecular profiles to evolving single-cell analytics, the characterization and compa …
Breast cancer is the quintessential example of how molecular characterization of tumor biology guides therapeutic decisions. From the …
Molecular subtyping of small cell lung cancer.
Liang J, Guan X, Bao G, Yao Y, Zhong X. Liang J, et al. Semin Cancer Biol. 2022 Nov;86(Pt 2):450-462. doi: 10.1016/j.semcancer.2022.05.010. Epub 2022 May 21. Semin Cancer Biol. 2022. PMID: 35609720 Review.
Based on the latest sequencing data for SCLC, thereafter, we discuss therapeutic opinions of SCLC from basic to clinic. This review may provide a basis for guiding the development of subsequent individualized precision-targeted therapy for SCLC patients to improve their cl …
Based on the latest sequencing data for SCLC, thereafter, we discuss therapeutic opinions of SCLC from basic to clinic. This review may prov …
Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial.
Xu B, Tu S, Song L, Jin Z, Yu B, Fu G, Zhou Y, Wang J, Chen Y, Pu J, Chen L, Qu X, Yang J, Liu X, Guo L, Shen C, Zhang Y, Zhang Q, Pan H, Fu X, Liu J, Zhao Y, Escaned J, Wang Y, Fearon WF, Dou K, Kirtane AJ, Wu Y, Serruys PW, Yang W, Wijns W, Guan C, Leon MB, Qiao S, Stone GW; FAVOR III China study group. Xu B, et al. Lancet. 2021 Dec 11;398(10317):2149-2159. doi: 10.1016/S0140-6736(21)02248-0. Epub 2021 Nov 4. Lancet. 2021. PMID: 34742368 Clinical Trial.
The 1-year primary endpoint occurred in 110 (Kaplan-Meier estimated rate 5.8%) participants in the QFR-guided group and in 167 (8.8%) participants in the angiography-guided group (difference, -3.0% [95% CI -4.7 to -1.4]; hazard ratio 0.65 [95% CI 0.51 to 0.83]; p=0. …
The 1-year primary endpoint occurred in 110 (Kaplan-Meier estimated rate 5.8%) participants in the QFR-guided group and in 167 (8.8%) …
Imaging-Navigated Surgery.
Lin Y, Zhang C, Liu C, Ma X, Yang Q, Guan B, Liu Z. Lin Y, et al. Adv Exp Med Biol. 2023;1199:87-106. doi: 10.1007/978-981-32-9902-3_5. Adv Exp Med Biol. 2023. PMID: 37460728
It is vitally important to guide or navigate therapeutic proceedings with a direct and visual approach in order to carefully undertake precision medical manipulations and efficiently evaluate the treatments. ...
It is vitally important to guide or navigate therapeutic proceedings with a direct and visual approach in order to carefully undertak …
Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Guan H, Wang P, Zhang P, Ruan C, Ou Y, Peng B, Zheng X, Lei J, Li B, Yan C, Li H. Guan H, et al. Nature. 2023 Aug;620(7974):669-675. doi: 10.1038/s41586-023-06349-1. Epub 2023 Jul 19. Nature. 2023. PMID: 37468628 Free PMC article.
Collectively, our work illustrates dynamic and diverse modes of multivalent nucleosomal engagement and methylation-guided deacetylation by Rpd3S, highlighting the exquisite complexity of epigenetic regulation with delicately designed multi-subunit enzymatic machineries in …
Collectively, our work illustrates dynamic and diverse modes of multivalent nucleosomal engagement and methylation-guided deacetylati …
Emerging Bioinspired Artificial Woods.
Yu ZL, Qin B, Ma ZY, Gao YC, Guan QF, Yang HB, Yu SH. Yu ZL, et al. Adv Mater. 2021 Jul;33(28):e2001086. doi: 10.1002/adma.202001086. Epub 2020 Jun 2. Adv Mater. 2021. PMID: 32483868 Review.
., low-density, high strength and stiffness, good toughness, and environmental sustainability) have made wood a natural source of inspiration that guides researchers to invent various wood-inspired materials. Herein, as an emerging material system, bioinspired artificial w …
., low-density, high strength and stiffness, good toughness, and environmental sustainability) have made wood a natural source of inspiratio …
Lighting up Micro-/Nanorobots with Fluorescence.
Yang M, Guo X, Mou F, Guan J. Yang M, et al. Chem Rev. 2023 Apr 12;123(7):3944-3975. doi: 10.1021/acs.chemrev.2c00062. Epub 2022 Sep 15. Chem Rev. 2023. PMID: 36108155 Review.
After the highlighted elucidation about MNRs of various propulsion mechanisms and the introductory information on fluorescence with emphasis on the fluorescent mechanisms and materials, we systematically illustrate the design and preparation strategies to integrate MNRs with fluo …
After the highlighted elucidation about MNRs of various propulsion mechanisms and the introductory information on fluorescence with emphasis …
Research Progress?on?Age?Determination?of?Venous?Thrombosis in Forensic Medicine.
Wang LL, Zhang FY, Liang XY, Wang CL, Zhao R, Guan DW. Wang LL, et al. Fa Yi Xue Za Zhi. 2019 Apr;35(2):171-177. doi: 10.12116/j.issn.1004-5619.2019.02.008. Epub 2019 Apr 25. Fa Yi Xue Za Zhi. 2019. PMID: 31135111 Free article. Review. Chinese, English.
This review summarizes the history of thrombus age estimation and recent advances in forensic medicine, and then gives a brief outlook for future research to provide reference for forensic identification of PTE and guide follow-up studies....
This review summarizes the history of thrombus age estimation and recent advances in forensic medicine, and then gives a brief outlook for f …
Expanding mTOR signaling.
Yang Q, Guan KL. Yang Q, et al. Cell Res. 2007 Aug;17(8):666-81. doi: 10.1038/cr.2007.64. Cell Res. 2007. PMID: 17680028 Review.
Thus, it is now even more critical that we precisely understand the underlying molecular mechanisms in order to directly guide the development and usage of anti-cancer drugs targeting the mTOR signaling pathway. ...
Thus, it is now even more critical that we precisely understand the underlying molecular mechanisms in order to directly guide the de …
1,154 results