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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1978 1
1979 1
1980 3
1981 1
1982 1
1983 3
1984 4
1985 1
1986 3
1987 3
1988 3
1989 2
1990 5
1991 6
1992 2
1993 2
1994 4
1995 5
1996 6
1997 7
1998 1
1999 7
2000 12
2001 13
2002 26
2003 11
2004 10
2005 13
2006 7
2007 17
2008 11
2009 15
2010 19
2011 19
2012 21
2013 21
2014 31
2015 43
2016 44
2017 42
2018 49
2019 33
2020 47
2021 46
2022 31
2023 33
2024 10

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Search Results

633 results

Results by year

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Page 1
The genetic basis of disease.
Jackson M, Marks L, May GHW, Wilson JB. Jackson M, et al. Essays Biochem. 2018 Dec 2;62(5):643-723. doi: 10.1042/EBC20170053. Print 2018 Dec 3. Essays Biochem. 2018. PMID: 30509934 Free PMC article. Review.
This review explores the genetic basis of human disease, including single gene disorders, chromosomal imbalances, epigenetics, cancer and complex disorders, and considers how our understanding and technological advances can be applied to provision of appropriate diagnosis, …
This review explores the genetic basis of human disease, including single gene disorders, chromosomal imbalances, epigenetics, cancer …
Tumor-infiltrating dendritic cell states are conserved across solid human cancers.
Gerhard GM, Bill R, Messemaker M, Klein AM, Pittet MJ. Gerhard GM, et al. J Exp Med. 2021 Jan 4;218(1):e20200264. doi: 10.1084/jem.20200264. J Exp Med. 2021. PMID: 33601412 Free PMC article. Review.
Here, we discuss our expanding view of DC heterogeneity in human tumors, as revealed with meta-analysis of single-cell transcriptome profiling studies. We further examine tumor-infiltrating DC states that are conserved across patients, cancer types, and species and conside …
Here, we discuss our expanding view of DC heterogeneity in human tumors, as revealed with meta-analysis of single-cell transcriptome …
Locally renewing resident synovial macrophages provide a protective barrier for the joint.
Culemann S, Grüneboom A, Nicolás-Ávila JÁ, Weidner D, Lämmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, Simon D, Haseloff RF, Ekici AB, Bäuerle T, Blasig IE, Vera J, Voehringer D, Kleyer A, Paulsen F, Schett G, Hidalgo A, Krönke G. Culemann S, et al. Nature. 2019 Aug;572(7771):670-675. doi: 10.1038/s41586-019-1471-1. Epub 2019 Aug 7. Nature. 2019. PMID: 31391580 Free PMC article.
Here we use fate-mapping approaches in conjunction with three-dimensional light-sheet fluorescence microscopy and single-cell RNA sequencing to perform a comprehensive spatiotemporal analysis of the composition, origin and differentiation of subsets of macrophages within h …
Here we use fate-mapping approaches in conjunction with three-dimensional light-sheet fluorescence microscopy and single-cell RNA seq …
Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature.
Ralser A, Dietl A, Jarosch S, Engelsberger V, Wanisch A, Janssen KP, Middelhoff M, Vieth M, Quante M, Haller D, Busch DH, Deng L, Mejías-Luque R, Gerhard M. Ralser A, et al. Gut. 2023 Jul;72(7):1258-1270. doi: 10.1136/gutjnl-2022-328075. Epub 2023 Apr 4. Gut. 2023. PMID: 37015754
DESIGN: We infected two Apc-mutant mouse models and C57BL/6 mice with H. pylori and conducted a comprehensive analysis of H. pylori-induced changes in intestinal immune responses and epithelial signatures via flow cytometry, chip cytometry, immunohistochemistry and single …
DESIGN: We infected two Apc-mutant mouse models and C57BL/6 mice with H. pylori and conducted a comprehensive analysis of H. pylori-induced …
The genetic landscape of high-risk neuroblastoma.
Pugh TJ, Morozova O, Attiyeh EF, Asgharzadeh S, Wei JS, Auclair D, Carter SL, Cibulskis K, Hanna M, Kiezun A, Kim J, Lawrence MS, Lichenstein L, McKenna A, Pedamallu CS, Ramos AH, Shefler E, Sivachenko A, Sougnez C, Stewart C, Ally A, Birol I, Chiu R, Corbett RD, Hirst M, Jackman SD, Kamoh B, Khodabakshi AH, Krzywinski M, Lo A, Moore RA, Mungall KL, Qian J, Tam A, Thiessen N, Zhao Y, Cole KA, Diamond M, Diskin SJ, Mosse YP, Wood AC, Ji L, Sposto R, Badgett T, London WB, Moyer Y, Gastier-Foster JM, Smith MA, Guidry Auvil JM, Gerhard DS, Hogarty MD, Jones SJ, Lander ES, Gabriel SB, Getz G, Seeger RC, Khan J, Marra MA, Meyerson M, Maris JM. Pugh TJ, et al. Nat Genet. 2013 Mar;45(3):279-84. doi: 10.1038/ng.2529. Epub 2013 Jan 20. Nat Genet. 2013. PMID: 23334666 Free PMC article.
The prospects of single-cell analysis in autoimmunity.
Sulen A, Islam S, Wolff ASB, Oftedal BE. Sulen A, et al. Scand J Immunol. 2020 Nov;92(5):e12964. doi: 10.1111/sji.12964. Epub 2020 Sep 29. Scand J Immunol. 2020. PMID: 32869859 Free article. Review.
Paralleling the development in the laboratory, and because of increasing complexity, the analysis of single-cell data is also constantly being updated with new algorithms and analysis platforms. ...The aim of this review is to remedy this by giving a balanced overview of t …
Paralleling the development in the laboratory, and because of increasing complexity, the analysis of single-cell data is also constan …
Organ at Risk Dose Constraints in SABR: A Systematic Review of Active Clinical Trials.
Gerhard SG, Palma DA, Arifin AJ, Louie AV, Li GJ, Al-Shafa F, Cheung P, Rodrigues GB, Bassim CW, Corkum MT. Gerhard SG, et al. Pract Radiat Oncol. 2021 Jul-Aug;11(4):e355-e365. doi: 10.1016/j.prro.2021.03.005. Pract Radiat Oncol. 2021. PMID: 34217495
For many OARs, modal dose constraints often matched a pre-existing publication, but no single pre-existing publication matched the modes of all OAR dose constraints. ...
For many OARs, modal dose constraints often matched a pre-existing publication, but no single pre-existing publication matched the mo …
Amblyopia.
Blair K, Cibis G, Zeppieri M, Gulani AC. Blair K, et al. 2024 Feb 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2024 Feb 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 28613640 Free Books & Documents.
Among children and young adults, amblyopia is the most common cause of decreased vision in a single eye, affecting approximately 2% to 4% of children. The development of this condition is often linked to factors such as visual deprivation, inadequate quality of visual stim …
Among children and young adults, amblyopia is the most common cause of decreased vision in a single eye, affecting approximately 2% t …
Symptomatic fever management in children: A systematic review of national and international guidelines.
Green C, Krafft H, Guyatt G, Martin D. Green C, et al. PLoS One. 2021 Jun 17;16(6):e0245815. doi: 10.1371/journal.pone.0245815. eCollection 2021. PLoS One. 2021. PMID: 34138848 Free PMC article.
A GRADE assessment was undertaken to assess the body of evidence related to a single question: the threshold for initiating antipyresis. Methods and results are reported according to the PRISMA statement. ...
A GRADE assessment was undertaken to assess the body of evidence related to a single question: the threshold for initiating antipyres …
Visualizing the disordered nuclear transport machinery in situ.
Yu M, Heidari M, Mikhaleva S, Tan PS, Mingu S, Ruan H, Reinkemeier CD, Obarska-Kosinska A, Siggel M, Beck M, Hummer G, Lemke EA. Yu M, et al. Nature. 2023 May;617(7959):162-169. doi: 10.1038/s41586-023-05990-0. Epub 2023 Apr 26. Nature. 2023. PMID: 37100914 Free PMC article.
Here we directly probed conformations of the vital FG-NUP98 inside NPCs in live cells and in permeabilized cells with an intact transport machinery by using a synthetic biology-enabled site-specific small-molecule labelling approach paired with highly time-resolved fluorescence m …
Here we directly probed conformations of the vital FG-NUP98 inside NPCs in live cells and in permeabilized cells with an intact transport ma …
633 results