Characterization of the nonlinear elastic behavior of chinchilla tympanic membrane using micro-fringe projection

Hear Res. 2016 Sep:339:1-11. doi: 10.1016/j.heares.2016.05.012. Epub 2016 May 27.

Abstract

The mechanical properties of an intact, full tympanic membrane (TM) inside the bulla of a fresh chinchilla were measured under quasi-static pressure from -1.0 kPa to 1.0 kPa applied on the TM lateral side. Images of the fringes projected onto the TM were acquired by a digital camera connected to a surgical microscope and analyzed using a phase-shift method to reconstruct the surface topography. The relationship between the applied pressure and the resulting volume displacement was determined and analyzed using a finite element model implementing a hyperelastic 2(nd)-order Ogden model. Through an inverse method, the best-fit model parameters for the TM were determined to allow the simulation results to agree with the experimental data. The nonlinear stress-strain relationship for the TM of a chinchilla was determined up to an equibiaxial tensile strain of 31% experienced by the TM in the experiments. The average Young's modulus of the chinchilla TM from ten bullas was determined as approximately 19 MPa.

Keywords: Chinchilla; Hyperelastic model; Micro-fringe projection; Static pressure; Tympanic membrane.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Animals
  • Biomechanical Phenomena
  • Chinchilla / physiology*
  • Computer Simulation
  • Elastic Modulus*
  • Finite Element Analysis
  • Otoscopy
  • Pressure
  • Stress, Mechanical
  • Tympanic Membrane / physiology*
  • Viscosity