Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses

Cell Mol Gastroenterol Hepatol. 2020;10(1):206-208.e3. doi: 10.1016/j.jcmgh.2020.02.008. Epub 2020 Mar 6.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anxiety / etiology
  • Anxiety / psychology
  • Behavior, Animal / physiology
  • Disease Models, Animal
  • Dysbiosis / complications
  • Dysbiosis / microbiology
  • Dysbiosis / pathology*
  • Dysbiosis / psychology
  • Female
  • Gastrointestinal Microbiome / physiology*
  • Humans
  • Intestinal Mucosa / cytology
  • Intestinal Mucosa / innervation
  • Intestinal Mucosa / microbiology
  • Intestinal Mucosa / pathology*
  • Male
  • Mice, Transgenic
  • Myosin-Light-Chain Kinase / genetics
  • Myosin-Light-Chain Kinase / metabolism*
  • Nociception / physiology
  • Permeability
  • Tight Junctions / pathology*

Substances

  • Myosin-Light-Chain Kinase