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Showing results for dex in xie
Search for dexin xie instead (2 results)
The neuroprotective effect of dexmedetomidine and its mechanism.
Hu Y, Zhou H, Zhang H, Sui Y, Zhang Z, Zou Y, Li K, Zhao Y, Xie J, Zhang L. Hu Y, et al. Front Pharmacol. 2022 Sep 20;13:965661. doi: 10.3389/fphar.2022.965661. eCollection 2022. Front Pharmacol. 2022. PMID: 36204225 Free PMC article. Review.
Dexmedetomidine (DEX) is a highly selective alpha2 receptor agonist that is routinely used in the clinic for sedation and anesthesia. ...Therefore, DEX can provide a crucial advantage in neurological recovery for patients with brain injury. ...
Dexmedetomidine (DEX) is a highly selective alpha2 receptor agonist that is routinely used in the clinic for sedation and anesthesia. …
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway.
Shi J, Yu T, Song K, Du S, He S, Hu X, Li X, Li H, Dong S, Zhang Y, Xie Z, Li C, Yu J. Shi J, et al. Redox Biol. 2021 May;41:101954. doi: 10.1016/j.redox.2021.101954. Epub 2021 Mar 21. Redox Biol. 2021. PMID: 33774474 Free PMC article.
Increasing lines of evidence identified that dexmedetomidine (DEX) exerted protective effects against sepsis-stimulated acute lung injury via anti-inflammation, anti-oxidation and anti-apoptosis. ...Moreover, HO-1-knockout mice or HO-1 siRNA transfected NR8383 cells were p …
Increasing lines of evidence identified that dexmedetomidine (DEX) exerted protective effects against sepsis-stimulated acute lung in …
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment.
Muhammad W, Zhu J, Zhai Z, Xie J, Zhou J, Feng X, Feng B, Pan Q, Li S, Venkatesan R, Li P, Cao H, Gao C. Muhammad W, et al. Acta Biomater. 2022 Aug;148:258-270. doi: 10.1016/j.actbio.2022.06.024. Epub 2022 Jun 18. Acta Biomater. 2022. PMID: 35724918 Free PMC article.
DEX was released faster from the PFTU@DEX NPs in a ROS environment, which could scavenge excessive ROS efficiently both in vitro and in vivo. The PFTU NPs and PFTU@DEX NPs showed no hemolysis and cytotoxicity. Free DEX, PFTU NPs and PFTU@DEX NPs …
DEX was released faster from the PFTU@DEX NPs in a ROS environment, which could scavenge excessive ROS efficiently both in vit …
Prebiotics-Encapsulated Probiotic Spores Regulate Gut Microbiota and Suppress Colon Cancer.
Zheng DW, Li RQ, An JX, Xie TQ, Han ZY, Xu R, Fang Y, Zhang XZ. Zheng DW, et al. Adv Mater. 2020 Nov;32(45):e2004529. doi: 10.1002/adma.202004529. Epub 2020 Oct 1. Adv Mater. 2020. PMID: 33006175
Through the host-guest chemistry between commercial Clostridium butyricum and chemically modified prebiotic dextran, prebiotics-encapsulated probiotic spores (spores-dex) are prepared. It is found that spores-dex can specifically enrich in colon cancers after oral a …
Through the host-guest chemistry between commercial Clostridium butyricum and chemically modified prebiotic dextran, prebiotics-encapsulated …
IL-6-induced cGGNBP2 encodes a protein to promote cell growth and metastasis in intrahepatic cholangiocarcinoma.
Li H, Lan T, Liu H, Liu C, Dai J, Xu L, Cai Y, Hou G, Xie K, Liao M, Li J, Huang J, Yuan K, Wang G, Zeng Y, Wu H. Li H, et al. Hepatology. 2022 Jun;75(6):1402-1419. doi: 10.1002/hep.32232. Epub 2021 Dec 21. Hepatology. 2022. PMID: 34758510 Free PMC article.
The biogenesis of cGGNBP2 was regulated by RNA-binding protein DEx-H Box Helicase 9, which was also mediated by IL-6 exposure. ...
The biogenesis of cGGNBP2 was regulated by RNA-binding protein DEx-H Box Helicase 9, which was also mediated by IL-6 exposure. ...
Dexmedetomidine abates myocardial ischemia reperfusion injury through inhibition of pyroptosis via regulation of miR-665/MEF2D/Nrf2 axis.
Wang L, Liu J, Wang Z, Qian X, Zhao Y, Wang Q, Dai N, Xie Y, Zeng W, Yang W, Bai X, Yang Y, Qian J. Wang L, et al. Biomed Pharmacother. 2023 Sep;165:115255. doi: 10.1016/j.biopha.2023.115255. Epub 2023 Aug 5. Biomed Pharmacother. 2023. PMID: 37549462 Free article.
Overexpression of miR-665 decreased the expression of MEF2D and blunted the protective effects of Dex in H9c2 cells. Moreover, the functional rescue experiment further verified that Dex regulated MEF2D/Nrf2 pathway via miR-665. In conclusion, Dex mitigates MI …
Overexpression of miR-665 decreased the expression of MEF2D and blunted the protective effects of Dex in H9c2 cells. Moreover, the fu …
Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway.
Zhang ZT, Xie K, Luo RJ, Zhang DY, He ZW, Li KF, Lin SH, Xu F. Zhang ZT, et al. Inflammopharmacology. 2023 Feb;31(1):423-438. doi: 10.1007/s10787-022-01117-5. Epub 2022 Dec 19. Inflammopharmacology. 2023. PMID: 36534240 Free PMC article.
Dexmedetomidine up-regulated the protein expression of p-AMPK and SIRT1 in lungs and EL-4 cells and facilitated the differentiation of naive CD4(+) T cells into Tregs in vitro. Meanwhile, DEX also increased the expression of Helios in Treg cells. CONCLUSIONS: DEX co …
Dexmedetomidine up-regulated the protein expression of p-AMPK and SIRT1 in lungs and EL-4 cells and facilitated the differentiation of naive …
Dexmedetomidine Ameliorates Postoperative Cognitive Dysfunction in Aged Mice.
Xie X, Shen Z, Hu C, Zhang K, Guo M, Wang F, Qin K. Xie X, et al. Neurochem Res. 2021 Sep;46(9):2415-2426. doi: 10.1007/s11064-021-03386-y. Epub 2021 Jun 23. Neurochem Res. 2021. PMID: 34159456
A mouse model of abdominal exploratory laparotomy-induced cognitive dysfunction was employed to explore the underlying mechanism of neuroprotective effects exerted by Dex in POCD. Aged mice were treated with Dex (20 g/kg) 20 min prior to surgery. ...Furthermore, …
A mouse model of abdominal exploratory laparotomy-induced cognitive dysfunction was employed to explore the underlying mechanism of neuropro …
Galangin mitigates glucocorticoid-induced osteoporosis by activating autophagy of BMSCs via triggering the PKA/CREB signaling pathway.
Zeng C, Wang S, Gu H, Chen F, Wang Z, Li J, Xie Z, Feng P, Shen H, Wu Y. Zeng C, et al. Acta Biochim Biophys Sin (Shanghai). 2023 Jun 26;55(8):1275-1287. doi: 10.3724/abbs.2023063. Acta Biochim Biophys Sin (Shanghai). 2023. PMID: 37365870 Free PMC article.
Our results show that GAL markedly mitigates the severity of dexamethasone (Dex)-induced osteoporosis in mice and potentiates osteogenic differentiation in mouse bone marrow-derived mesenchymal stem cells (BMSCs). Furthermore, GAL also significantly counteracts Dex- …
Our results show that GAL markedly mitigates the severity of dexamethasone (Dex)-induced osteoporosis in mice and potentiates osteoge …
Diffusion time dependency of extracellular diffusion.
Xu J, Xie J, Semmineh NB, Devan SP, Jiang X, Gore JC. Xu J, et al. Magn Reson Med. 2023 Jun;89(6):2432-2440. doi: 10.1002/mrm.29594. Epub 2023 Feb 5. Magn Reson Med. 2023. PMID: 36740894 Free PMC article.
DMRI measurements were performed on samples consisting of liposomes containing heavy water(D(2) O, deuterium oxide) dispersed in regular water (H(2) O). Dex was obtained over a broad t range (1-1000 ms) and then fit power-law equations Dex(t) = Dconst + const . t-t …
DMRI measurements were performed on samples consisting of liposomes containing heavy water(D(2) O, deuterium oxide) dispersed in regular wat …
162 results