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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1983 1
1989 1
1990 1
1992 2
1993 1
1994 3
1995 2
1996 1
1997 5
1998 5
1999 5
2000 5
2001 5
2003 9
2004 9
2005 15
2006 17
2007 12
2008 25
2009 19
2010 30
2011 25
2012 29
2013 35
2014 46
2015 60
2016 72
2017 69
2018 93
2019 111
2020 129
2021 154
2022 135
2023 160
2024 61

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1,214 results

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Page 1
Human chimeric antigen receptor macrophages for cancer immunotherapy.
Klichinsky M, Ruella M, Shestova O, Lu XM, Best A, Zeeman M, Schmierer M, Gabrusiewicz K, Anderson NR, Petty NE, Cummins KD, Shen F, Shan X, Veliz K, Blouch K, Yashiro-Ohtani Y, Kenderian SS, Kim MY, O'Connor RS, Wallace SR, Kozlowski MS, Marchione DM, Shestov M, Garcia BA, June CH, Gill S. Klichinsky M, et al. Nat Biotechnol. 2020 Aug;38(8):947-953. doi: 10.1038/s41587-020-0462-y. Epub 2020 Mar 23. Nat Biotechnol. 2020. PMID: 32361713 Free PMC article.
In two solid tumor xenograft mouse models, a single infusion of human CAR-Ms decreased tumor burden and prolonged overall survival. Characterization of CAR-M activity showed that CAR-Ms expressed pro-inflammatory cytokines and chemokines, converted bystander M2 macr …
In two solid tumor xenograft mouse models, a single infusion of human CAR-Ms decreased tumor burden and prolonged overall survival. C …
Minimal Residual Disease Detection in Acute Lymphoblastic Leukemia.
Kruse A, Abdel-Azim N, Kim HN, Ruan Y, Phan V, Ogana H, Wang W, Lee R, Gang EJ, Khazal S, Kim YM. Kruse A, et al. Int J Mol Sci. 2020 Feb 5;21(3):1054. doi: 10.3390/ijms21031054. Int J Mol Sci. 2020. PMID: 32033444 Free PMC article. Review.
Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation.
Niu J, Tsai HH, Hoi KK, Huang N, Yu G, Kim K, Baranzini SE, Xiao L, Chan JR, Fancy SPJ. Niu J, et al. Nat Neurosci. 2019 May;22(5):709-718. doi: 10.1038/s41593-019-0369-4. Epub 2019 Apr 15. Nat Neurosci. 2019. PMID: 30988524 Free PMC article.
Disruption of the blood-brain barrier (BBB) is critical to initiation and perpetuation of disease in multiple sclerosis (MS). We report an interaction between oligodendroglia and vasculature in MS that distinguishes human white matter injury from normal rodent demye …
Disruption of the blood-brain barrier (BBB) is critical to initiation and perpetuation of disease in multiple sclerosis (MS). We repo …
ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis.
Qian Y, Arellano G, Ifergan I, Lin J, Snowden C, Kim T, Thomas JJ, Law C, Guan T, Balabanov RD, Kaech SM, Miller SD, Choi J. Qian Y, et al. Cell Rep. 2021 Aug 24;36(8):109602. doi: 10.1016/j.celrep.2021.109602. Cell Rep. 2021. PMID: 34433042 Free PMC article.
Deletion of ZEB1 protects against experimental autoimmune encephalitis (EAE), a mouse model of multiple sclerosis (MS). Mechanistically, ZEB1 in CD4(+) T cells is required for pathogenic Th1 and Th17 differentiation. ...Underscoring its clinical relevance, ZEB1 and JAK2 do …
Deletion of ZEB1 protects against experimental autoimmune encephalitis (EAE), a mouse model of multiple sclerosis (MS). Mechanistical …
Identification of Histone Lysine Acetoacetylation as a Dynamic Post-Translational Modification Regulated by HBO1.
Gao Y, Sheng X, Tan D, Kim S, Choi S, Paudel S, Lee T, Yan C, Tan M, Kim KM, Cho SS, Ki SH, Huang H, Zhao Y, Lee S. Gao Y, et al. Adv Sci (Weinh). 2023 Sep;10(25):e2300032. doi: 10.1002/advs.202300032. Epub 2023 Jun 29. Adv Sci (Weinh). 2023. PMID: 37382194 Free PMC article.
This protein modification is comprehensively validated using chemical and biochemical approaches, including HPLC co-elution and MS/MS analysis using synthetic peptides, Western blot, and isotopic labeling. ...
This protein modification is comprehensively validated using chemical and biochemical approaches, including HPLC co-elution and MS/ …
A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.
Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ Jr, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D; University of California, San Francisco MS-EPIC Team; Guo CY, Green AJ, Bove RM, DeRisi JL, Gelfand JM, Cree BAC, Zamvil SS, Baranzini SE, Hauser SL, Wilson MR. Ramesh A, et al. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22932-22943. doi: 10.1073/pnas.2008523117. Epub 2020 Aug 28. Proc Natl Acad Sci U S A. 2020. PMID: 32859762 Free PMC article.
While we identified memory B cells and plasmablast/plasma cells with highly similar Ig heavy-chain sequences across MS subjects, similarities were also identified with ONDs and HCs. No viral transcripts, including from Epstein-Barr virus, were detected. Our findings suppor …
While we identified memory B cells and plasmablast/plasma cells with highly similar Ig heavy-chain sequences across MS subjects, simi …
BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep.
Rojo D, Dal Cengio L, Badner A, Kim S, Sakai N, Greene J, Dierckx T, Mehl LC, Eisinger E, Ransom J, Arellano-Garcia C, Gumma ME, Soyk RL, Lewis CM, Lam M, Weigel MK, Damonte VM, Yalçın B, Jones SE, Ollila HM, Nishino S, Gibson EM. Rojo D, et al. Neuron. 2023 Nov 15;111(22):3604-3618.e11. doi: 10.1016/j.neuron.2023.08.002. Epub 2023 Aug 31. Neuron. 2023. PMID: 37657440
Lastly, we show that sleep fragmentation is associated with increased prevalence of the demyelinating disorder multiple sclerosis (MS), suggesting a link between MS and sleep that requires further investigation. ...
Lastly, we show that sleep fragmentation is associated with increased prevalence of the demyelinating disorder multiple sclerosis (MS …
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
Venkateswaran N, Lafita-Navarro MC, Hao YH, Kilgore JA, Perez-Castro L, Braverman J, Borenstein-Auerbach N, Kim M, Lesner NP, Mishra P, Brabletz T, Shay JW, DeBerardinis RJ, Williams NS, Yilmaz OH, Conacci-Sorrell M. Venkateswaran N, et al. Genes Dev. 2019 Sep 1;33(17-18):1236-1251. doi: 10.1101/gad.327056.119. Epub 2019 Aug 15. Genes Dev. 2019. PMID: 31416966 Free PMC article.
Using high-performance liquid chromatography (HPLC)-tandem mass spectrometry (LC-MS/MS), we found that MYC increased intracellular levels of tryptophan and tryptophan metabolites in the kynurenine pathway. ...
Using high-performance liquid chromatography (HPLC)-tandem mass spectrometry (LC-MS/MS), we found that MYC increased intracell …
Nonalcoholic Fatty Liver Disease and Metabolic Syndrome.
Kim D, Touros A, Kim WR. Kim D, et al. Clin Liver Dis. 2018 Feb;22(1):133-140. doi: 10.1016/j.cld.2017.08.010. Epub 2017 Oct 21. Clin Liver Dis. 2018. PMID: 29128053 Review.
The relationship between NAFLD and MS is complex and may be bidirectionally associated. NAFLD is strongly associated with MS, the components of which include abdominal obesity, hyperglycemia, hypertension, and dyslipidemia. NAFLD associated with certain genetic fact …
The relationship between NAFLD and MS is complex and may be bidirectionally associated. NAFLD is strongly associated with MS, …
Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis.
Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. Pröbstel AK, et al. Sci Immunol. 2020 Nov 20;5(53):eabc7191. doi: 10.1126/sciimmunol.abc7191. Sci Immunol. 2020. PMID: 33219152 Free PMC article.
Changes in gut microbiota composition and a diverse role of B cells have recently been implicated in multiple sclerosis (MS), a central nervous system (CNS) autoimmune disease. Immunoglobulin A (IgA) is a key regulator at the mucosal interface. However, whether gut microbi …
Changes in gut microbiota composition and a diverse role of B cells have recently been implicated in multiple sclerosis (MS), a centr …
1,214 results