Targeted inhibition of the methyltransferase SETD8 synergizes with the Wee1 inhibitor adavosertib in restraining glioblastoma growth.
Della Monica R, Buonaiuto M, Cuomo M, Pagano C, Trio F, Costabile D, de Riso G, Cicala FS, Raia M, Franca RA, Del Basso De Caro M, Sorrentino D, Navarra G, Coppola L, Tripodi L, Pastore L, Hench J, Frank S, Schonauer C, Catapano G, Bifulco M, Chiariotti L, Visconti R.
Della Monica R, et al.
Cell Death Dis. 2023 Sep 27;14(9):638. doi: 10.1038/s41419-023-06167-3.
Cell Death Dis. 2023.
PMID: 37758718
Free PMC article.
Despite intense research efforts, glioblastoma remains an incurable brain tumor with a dismal median survival time of 15 months. Thus, identifying new therapeutic targets is an urgent need. ...
Despite intense research efforts, glioblastoma remains an incurable brain tumor with a dismal median survival time of 15 months. Thus …