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2005 | 2 |
2021 | 1 |
2022 | 1 |
2024 | 0 |
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bogren gu
(22 results)?
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Mol Cell. 2022 May 5;82(9):1643-1659.e10. doi: 10.1016/j.molcel.2022.03.007. Epub 2022 Mar 24.
Mol Cell. 2022.
PMID: 35334231
Free PMC article.
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.
Figley MD, Gu W, Nanson JD, Shi Y, Sasaki Y, Cunnea K, Malde AK, Jia X, Luo Z, Saikot FK, Mosaiab T, Masic V, Holt S, Hartley-Tassell L, McGuinness HY, Manik MK, Bosanac T, Landsberg MJ, Kerry PS, Mobli M, Hughes RO, Milbrandt J, Kobe B, DiAntonio A, Ve T.
Figley MD, et al.
Neuron. 2021 Apr 7;109(7):1118-1136.e11. doi: 10.1016/j.neuron.2021.02.009. Epub 2021 Mar 2.
Neuron. 2021.
PMID: 33657413
Free PMC article.
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Hepatitis C virus NS3-4A serine protease inhibitors: SAR of P'2 moiety with improved potency.
Arasappan A, Njoroge FG, Chan TY, Bennett F, Bogen SL, Chen K, Gu H, Hong L, Jao E, Liu YT, Lovey RG, Parekh T, Pike RE, Pinto P, Santhanam B, Venkatraman S, Vaccaro H, Wang H, Yang X, Zhu Z, Mckittrick B, Saksena AK, Girijavallabhan V, Pichardo J, Butkiewicz N, Ingram R, Malcolm B, Prongay A, Yao N, Marten B, Madison V, Kemp S, Levy O, Lim-Wilby M, Tamura S, Ganguly AK.
Arasappan A, et al.
Bioorg Med Chem Lett. 2005 Oct 1;15(19):4180-4. doi: 10.1016/j.bmcl.2005.06.091.
Bioorg Med Chem Lett. 2005.
PMID: 16087332
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Hepatitis C virus NS3-4A serine protease inhibitors: use of a P2-P1 cyclopropyl alanine combination for improved potency.
Bogen S, Saksena AK, Arasappan A, Gu H, Njoroge FG, Girijavallabhan V, Pichardo J, Butkiewicz N, Prongay A, Madison V.
Bogen S, et al.
Bioorg Med Chem Lett. 2005 Oct 15;15(20):4515-9. doi: 10.1016/j.bmcl.2005.07.009.
Bioorg Med Chem Lett. 2005.
PMID: 16112862
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