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Page 1
PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.
Huang T, Yang Y, Song X, Wan X, Wu B, Sastry N, Horbinski CM, Zeng C, Tiek D, Goenka A, Liu F, Brennan CW, Kessler JA, Stupp R, Nakano I, Sulman EP, Nishikawa R, James CD, Zhang W, Xu W, Hu B, Cheng SY. Huang T, et al. Among authors: hu b. Mol Cell. 2021 Mar 18;81(6):1276-1291.e9. doi: 10.1016/j.molcel.2021.01.015. Epub 2021 Feb 3. Mol Cell. 2021. PMID: 33539787 Free PMC article.
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z, Lim J, Wang Q, Purtell K, Wu S, Palomo GM, Tan H, Manfredi G, Zhao Y, Peng J, Hu B, Chen S, Yue Z. Deng Z, et al. Among authors: hu b. Autophagy. 2020 May;16(5):917-931. doi: 10.1080/15548627.2019.1644076. Epub 2019 Jul 30. Autophagy. 2020. PMID: 31362587 Free PMC article.
Therefore, our results reveal a mechanism whereby pathogenic SQSTM1 mutants inhibit selective autophagy and disrupt NFE2L2 anti-oxidative stress response underlying the neurotoxicity in ALS-FTLD.Abbreviations: ALS: amyotrophic lateral sclerosis; FTLD: frontotemporal lobar degener …
Therefore, our results reveal a mechanism whereby pathogenic SQSTM1 mutants inhibit selective autophagy and disrupt NFE2L2 anti-oxidative st …
SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway.
Zhou C, Liu C, Liu W, Chen W, Yin Y, Li CW, Hsu JL, Sun J, Zhou Q, Li H, Hu B, Fu P, Atyah M, Ma Q, Xu Y, Dong Q, Hung MC, Ren N. Zhou C, et al. Among authors: hu b. Theranostics. 2020 Mar 25;10(10):4627-4643. doi: 10.7150/thno.42869. eCollection 2020. Theranostics. 2020. PMID: 32292519 Free PMC article.
Hepatocellular carcinoma (HCC) remains one of the most refractory malignancies worldwide. Schlafen family member 11 (SLFN11) has been reported to play an important role in inhibiting the production of human immunodeficiency virus 1 (HIV-1). ...
Hepatocellular carcinoma (HCC) remains one of the most refractory malignancies worldwide. Schlafen family member 11 (SLFN11) has been …
NF-κB and Keap1 Interaction Represses Nrf2-Mediated Antioxidant Response in Rabbit Hemorrhagic Disease Virus Infection.
Hu B, Wei H, Song Y, Chen M, Fan Z, Qiu R, Zhu W, Xu W, Wang F. Hu B, et al. J Virol. 2020 May 4;94(10):e00016-20. doi: 10.1128/JVI.00016-20. Print 2020 May 4. J Virol. 2020. PMID: 32161178 Free PMC article.
The rabbit hemorrhagic disease virus (RHDV), which belongs to the family Caliciviridae and the genus Lagovirus, causes lethal fulminant hepatitis in rabbits. ...We showed that RHDV replication causes a remarkable increase in reactive oxygen species (ROS), which is simultan …
The rabbit hemorrhagic disease virus (RHDV), which belongs to the family Caliciviridae and the genus Lagovirus, causes lethal fulmina …
Low‑intensity pulsed ultrasound promotes periodontal ligament stem cell migration through TWIST1‑mediated SDF‑1 expression.
Wang Y, Li J, Qiu Y, Hu B, Chen J, Fu T, Zhou P, Song J. Wang Y, et al. Among authors: hu b. Int J Mol Med. 2018 Jul;42(1):322-330. doi: 10.3892/ijmm.2018.3592. Epub 2018 Mar 27. Int J Mol Med. 2018. PMID: 29620151 Free PMC article.
Wound healing and transwell assays were conducted to assess the migration-promoting effect of LIPUS. A potential upstream gene of SDF-1, twist family bHLH transcription factor 1 (TWIST1), was silenced by small interfering (si) RNA transfection. ...
Wound healing and transwell assays were conducted to assess the migration-promoting effect of LIPUS. A potential upstream gene of SDF-1, twi …
Low SLC29A1 expression is associated with poor prognosis in patients with hepatocellular carcinoma.
Gao PT, Cheng JW, Gong ZJ, Hu B, Sun YF, Cao Y, Qiu SJ, Zhou J, Fan J, Yang XR. Gao PT, et al. Among authors: hu b. Am J Cancer Res. 2017 Dec 1;7(12):2465-2477. eCollection 2017. Am J Cancer Res. 2017. PMID: 29312800 Free PMC article.
We systematically screened the expression of transporter genes in HCC samples and found that solute carrier family 29 member A1 (SLC29A1) expression was significantly elevated in human HCC cells compared with para-carcinoma cell samples. ...Further microarray-based gene ex …
We systematically screened the expression of transporter genes in HCC samples and found that solute carrier family 29 member A1 (SLC2 …
Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration.
Tang Z, Hu B, Zang F, Wang J, Zhang X, Chen H. Tang Z, et al. Among authors: hu b. Cell Death Dis. 2019 Jul 1;10(7):510. doi: 10.1038/s41419-019-1701-3. Cell Death Dis. 2019. PMID: 31263165 Free PMC article.
Intervertebral disc (IVD) degeneration is known to aggravate with age and oxidative stress is implicated in the pathogenesis of many age-related diseases. Nuclear factor (erythroid-derived-2)-like 2 (Nrf2) can confer adaptive protection against oxidative and proteotoxic st …
Intervertebral disc (IVD) degeneration is known to aggravate with age and oxidative stress is implicated in the pathogenesis of many age-rel …
Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma.
Zhang X, Yang XR, Sun C, Hu B, Sun YF, Huang XW, Wang Z, He YF, Zeng HY, Qiu SJ, Cao Y, Fan J, Zhou J. Zhang X, et al. Among authors: hu b. Cancer Lett. 2015 Sep 28;366(1):112-22. doi: 10.1016/j.canlet.2015.06.014. Epub 2015 Jun 25. Cancer Lett. 2015. PMID: 26118777
Gene microarray analysis shows that reduced PML expression significantly down-regulates expression of aldehyde dehydrogenase 3 family member A1 (ALDH3A1). ALDH3A1 depression facilitates accumulation of ATO-induced reactive oxygen species. ...
Gene microarray analysis shows that reduced PML expression significantly down-regulates expression of aldehyde dehydrogenase 3 family …
Haplotypes of 20 Y-chromosomal STRs in a population sample from southeast China (Chaoshan area).
Shi MS, Tang JP, Bai RF, Yu XJ, Lv JY, Hu B. Shi MS, et al. Among authors: hu b. Int J Legal Med. 2007 Nov;121(6):455-62. doi: 10.1007/s00414-007-0186-2. Epub 2007 Jul 20. Int J Legal Med. 2007. PMID: 17641908
The haplotype diversity value calculated from all 20 loci combined was 0.9997, which is informative. Furthermore, 80 father-son pairs, previously confirmed by autosomal STR analysis, were typed using the same 20 Y-STR loci, and four mutation events were identified at the Y …
The haplotype diversity value calculated from all 20 loci combined was 0.9997, which is informative. Furthermore, 80 father-son pairs …
13 results