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Bixasteroid, a new compound from the fruits of Bixa orellana and its anti-inflammatory activity.
Nat Prod Res. 2023 Feb;37(3):404-410. doi: 10.1080/14786419.2021.1974436. Epub 2021 Sep 10.
Nat Prod Res. 2023.
PMID: 34507510
Bixasteroid (1), one new steroid together with five known compounds (2-6), were isolated from the ethyl acetate fraction of ethanol extract of Bixa orellana fruits. All of these known compounds were isolated from the plant for the first time. ...
Bixasteroid (1), one new steroid together with five known compounds (2-6), were isolated from the ethyl acetate fraction of ethanol extract …
Bixin Protects Against Kidney Interstitial Fibrosis Through Promoting STAT6 Degradation.
Li J, Yang Y, Wei S, Chen L, Xue L, Tian H, Tao S.
Li J, et al.
Front Cell Dev Biol. 2020 Nov 17;8:576988. doi: 10.3389/fcell.2020.576988. eCollection 2020.
Front Cell Dev Biol. 2020.
PMID: 33313043
Free PMC article.
Bixin, a natural carotenoid extracted from the seeds of Bixa orellana, has antioxidant and anti-inflammation effects. However, the pharmacological effects and underlying mechanisms of bixin in kidney interstitial fibrosis remain unknown. ...
Bixin, a natural carotenoid extracted from the seeds of Bixa orellana, has antioxidant and anti-inflammation effects. However, the ph …
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Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae.
Chai F, Wang Y, Mei X, Yao M, Chen Y, Liu H, Xiao W, Yuan Y.
Chai F, et al.
Microb Cell Fact. 2017 Mar 29;16(1):54. doi: 10.1186/s12934-017-0665-1.
Microb Cell Fact. 2017.
PMID: 28356104
Free PMC article.
Moreover, an optimal CrtZ/CCD combination and a titer of 351 mug/L crocetin were obtained by combinatorial screening of CrtZs from nine species and four CCDs from Crocus. Then through screening of heterologous ALDs from Bixa orellana (Bix_ALD) and Synechocystis sp. PCC6803 …
Moreover, an optimal CrtZ/CCD combination and a titer of 351 mug/L crocetin were obtained by combinatorial screening of CrtZs from nine spec …
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Bixin Confers Prevention against Ureteral Obstruction-Caused Renal Interstitial Fibrosis through Activation of the Nuclear Factor Erythroid-2-Related Factor2 Pathway in Mice.
Li J, Yang Y, Wei S, Chen L, Xue L, Tian H, Tao S.
Li J, et al.
J Agric Food Chem. 2020 Aug 5;68(31):8321-8329. doi: 10.1021/acs.jafc.0c03674. Epub 2020 Jul 24.
J Agric Food Chem. 2020.
PMID: 32706966
Bixin is a natural carotenoid isolated from the seeds of Bixa orellana, with numerous important pharmacological activities, including antioxidant and antifibrotic effects. ...
Bixin is a natural carotenoid isolated from the seeds of Bixa orellana, with numerous important pharmacological activities, including …
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