Isolated prenatal ultrasound findings predict the postnatal course in gastroschisis

Pediatr Surg Int. 2015 Apr;31(4):381-7. doi: 10.1007/s00383-015-3675-2. Epub 2015 Feb 20.

Abstract

Purpose: The aim of the study was to identify which prenatal ultrasonographic findings in fetuses with gastroschisis correlate with complicated postnatal outcome.

Methods: Ultrasound findings at the 30th week of pregnancy and medical reports were statistically analyzed to identify independent prenatal ultrasonographic predictors of postnatal outcome.

Results: Completed prenatal data were gathered from 64 pregnancies. Prenatal intra-abdominal bowel dilatation (cutoff 10 mm) correlated with the presence of atresia (p < 0.01), longer administration of parenteral nutrition, extended hospital stay (median 53 vs. 21 days; 68 vs. 36 days, both p < 0.05), and greater number of additional surgical procedures (p < 0.05). Infants with antenatal presence of thickened bowel wall (greater than or equal to 3 mm) required longer administration of parenteral nutrition (median 34 vs. 20 days; p < 0.01) and prolonged stay (median 44 vs. 37 days; p < 0.05). Presence of oligohydramnion (amniotic fluid index below 8 cm) was connected with longer administration of parenteral nutrition in newborns (median 30 vs. 16 days; p < 0.05).

Conclusion: The isolated presence of oligohydramnion with amniotic fluid index below 8 cm, thickened bowel wall equal to or more than 3 mm and the prenatal intra-abdominal dilatation with 10 mm cutoff had significant predictive value for the adverse postnatal outcome of patients with gastroschisis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Gastroschisis / diagnostic imaging*
  • Gastroschisis / embryology
  • Humans
  • Infant, Newborn
  • Male
  • Postnatal Care / methods*
  • Pregnancy
  • Prognosis
  • Reproducibility of Results
  • Retrospective Studies
  • Ultrasonography, Prenatal / methods*
  • Young Adult