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1994 1
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2020 3
2021 4
2022 3
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2024 0

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22 results

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Page 1
Adoptive cell therapy of triple negative breast cancer with redirected cytokine-induced killer cells.
Sommaggio R, Cappuzzello E, Dalla Pietà A, Tosi A, Palmerini P, Carpanese D, Nicolè L, Rosato A. Sommaggio R, et al. Oncoimmunology. 2020 Jun 11;9(1):1777046. doi: 10.1080/2162402X.2020.1777046. Oncoimmunology. 2020. PMID: 32923140 Free PMC article.
They represent an attractive approach for cell-based immunotherapy, as they do not require antigen-specific priming for tumor cell recognition, and can be rapidly expanded in vitro. ...Moreover, this approach almost completely abolished metastasis spreading and dramaticall …
They represent an attractive approach for cell-based immunotherapy, as they do not require antigen-specific priming for tumor cell re …
Diagnostic Accuracy of a New Antigen Test for SARS-CoV-2 Detection.
Di Domenico M, De Rosa A, Di Gaudio F, Internicola P, Bettini C, Salzano N, Castrianni D, Marotta A, Boccellino M. Di Domenico M, et al. Int J Environ Res Public Health. 2021 Jun 10;18(12):6310. doi: 10.3390/ijerph18126310. Int J Environ Res Public Health. 2021. PMID: 34200827 Free PMC article.
The aim of this study was to evaluate the diagnostic accuracy of a new cyto-salivary antigen test aimed at detecting the presence of antigens for SARS-CoV-2, as compared by the gold standard RT-PCR and a lateral flow test. ...CONCLUSIONS: The new cyto-salivary an …
The aim of this study was to evaluate the diagnostic accuracy of a new cyto-salivary antigen test aimed at detecting the presence of …
B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartments.
Hernández-Pérez S, Vainio M, Kuokkanen E, Šuštar V, Petrov P, Forstén S, Paavola V, Rajala J, Awoniyi LO, Sarapulov AV, Vihinen H, Jokitalo E, Bruckbauer A, Mattila PK. Hernández-Pérez S, et al. J Cell Sci. 2019 Dec 20;133(5):jcs235192. doi: 10.1242/jcs.235192. J Cell Sci. 2019. PMID: 31780582 Free article.
In order to mount high-affinity antibody responses, B cells internalise specific antigens and process them into peptides loaded onto MHCII for presentation to T helper cells (T(H) cells). ...Here, we performed a systematic microscopy-based analysis of antigen traffi …
In order to mount high-affinity antibody responses, B cells internalise specific antigens and process them into peptides loaded onto …
Visualization and Quantitative Analysis of the Actin Cytoskeleton Upon B Cell Activation.
Šuštar V, Vainio M, Mattila PK. Šuštar V, et al. Methods Mol Biol. 2018;1707:243-257. doi: 10.1007/978-1-4939-7474-0_18. Methods Mol Biol. 2018. PMID: 29388113 Free article. Review.
Polymerization of actin monomers into filaments provides the force required for B cell spreading on the antigen-presenting cell (APC). Interestingly, the actin network also participates in cellular signaling at multiple levels. ...Here, we present the usage of TIRF microsc …
Polymerization of actin monomers into filaments provides the force required for B cell spreading on the antigen-presenting cell (APC) …
The safety of atezolizumab plus chemotherapy for the treatment of metastatic lung cancer.
Manzo A, Carillio G, Montanino A, Sforza V, Palumbo G, Esposito G, Costanzo R, Sandomenico C, La Manna C, Martucci N, La Rocca A, De Luca G, Piccirillo MC, De Cecio R, Botti G, Totaro G, Muto P, Picone C, Normanno N, Morabito A. Manzo A, et al. Expert Opin Drug Saf. 2020 Jul;19(7):775-783. doi: 10.1080/14740338.2020.1767584. Epub 2020 May 26. Expert Opin Drug Saf. 2020. PMID: 32400223 Review.
A specific hybridisation internalisation probe (SHIP) enables precise live-cell and super-resolution imaging of internalized cargo.
Hernández-Pérez S, Mattila PK. Hernández-Pérez S, et al. Sci Rep. 2022 Jan 12;12(1):620. doi: 10.1038/s41598-021-04544-6. Sci Rep. 2022. PMID: 35022457 Free PMC article.
Here, we adopted the SHIP assay to study the trafficking of receptor/ligand complexes using B lymphocytes and B cell receptor-mediated antigen internalization as a model system. Our study demonstrates the potential of the SHIP assay for improving the imaging of internalize …
Here, we adopted the SHIP assay to study the trafficking of receptor/ligand complexes using B lymphocytes and B cell receptor-mediated an …
Hyaluronan is a natural and effective immunological adjuvant for protein-based vaccines.
Dalla Pietà A, Carpanese D, Grigoletto A, Tosi A, Dalla Santa S, Pedersen GK, Christensen D, Meléndez-Alafort L, Barbieri V, De Benedictis P, Pasut G, Montagner IM, Rosato A. Dalla Pietà A, et al. Cell Mol Immunol. 2021 May;18(5):1197-1210. doi: 10.1038/s41423-021-00667-y. Epub 2021 Mar 24. Cell Mol Immunol. 2021. PMID: 33762685 Free PMC article.
We explored the application of the natural polymer hyaluronan (HA) as a promising immunological adjuvant for protein-based vaccines. Chemical conjugation of HA to antigens strongly increased their immunogenicity, reduced booster requirements, and allowed antigen dos …
We explored the application of the natural polymer hyaluronan (HA) as a promising immunological adjuvant for protein-based vaccines. Chemica …
Innovative therapeutic strategy for B-cell malignancies that combines obinutuzumab and cytokine-induced killer cells.
Dalla Pietà A, Cappuzzello E, Palmerini P, Ventura A, Visentin A, Astori G, Chieregato K, Mozzo V, Perbellini O, Tisi MC, Trentin L, Visco C, Ruggeri M, Sommaggio R, Rosato A. Dalla Pietà A, et al. J Immunother Cancer. 2021 Jul;9(7):e002475. doi: 10.1136/jitc-2021-002475. J Immunother Cancer. 2021. PMID: 34272306 Free PMC article.
Promising therapeutic success has been achieved with the infusion of CD19 chimeric antigen receptor-T cells, but several limits still restrain the administration to a limited proportion of patients. This unmet clinical need might be fulfilled by an adoptive immunotherapy a …
Promising therapeutic success has been achieved with the infusion of CD19 chimeric antigen receptor-T cells, but several limits still …
22 results