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Year Number of Results
1996 5
1997 2
1999 2
2000 4
2001 2
2002 1
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2004 2
2006 1
2007 2
2008 1
2009 1
2010 2
2011 2
2013 1
2014 1
2015 1
2016 2
2018 2
2020 4
2021 1
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2023 3
2024 2

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45 results

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Page 1
Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury.
STARRT-AKI Investigators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group; United Kingdom Critical Care Research Group; Canadian Nephrology Trials Network; Irish Critical Care Trials Group; Bagshaw SM, Wald R, Adhikari NKJ, Bellomo R, da Costa BR, Dreyfuss D, Du B, Gallagher MP, Gaudry S, Hoste EA, Lamontagne F, Joannidis M, Landoni G, Liu KD, McAuley DF, McGuinness SP, Neyra JA, Nichol AD, Ostermann M, Palevsky PM, Pettilä V, Quenot JP, Qiu H, Rochwerg B, Schneider AG, Smith OM, Thomé F, Thorpe KE, Vaara S, Weir M, Wang AY, Young P, Zarbock A. STARRT-AKI Investigators, et al. N Engl J Med. 2020 Jul 16;383(3):240-251. doi: 10.1056/NEJMoa2000741. N Engl J Med. 2020. PMID: 32668114 Free article. Clinical Trial.
At 90 days, death had occurred in 643 patients (43.9%) in the accelerated-strategy group and in 639 (43.7%) in the standard-strategy group (relative risk, 1.00; 95% confidence interval [CI], 0.93 to 1.09; P = 0.92). Among survivors at 90 days, continued dependence on renal …
At 90 days, death had occurred in 643 patients (43.9%) in the accelerated-strategy group and in 639 (43.7%) in the standard-strategy group ( …
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide.
Andrikopoulos P, Aron-Wisnewsky J, Chakaroun R, Myridakis A, Forslund SK, Nielsen T, Adriouch S, Holmes B, Chilloux J, Vieira-Silva S, Falony G, Salem JE, Andreelli F, Belda E, Kieswich J, Chechi K, Puig-Castellvi F, Chevalier M, Le Chatelier E, Olanipekun MT, Hoyles L, Alves R, Helft G, Isnard R, Køber L, Coelho LP, Rouault C, Gauguier D, Gøtze JP, Prifti E, Froguel P; MetaCardis Consortium; Zucker JD, Bäckhed F, Vestergaard H, Hansen T, Oppert JM, Blüher M, Nielsen J, Raes J, Bork P, Yaqoob MM, Stumvoll M, Pedersen O, Ehrlich SD, Clément K, Dumas ME. Andrikopoulos P, et al. Nat Commun. 2023 Sep 20;14(1):5843. doi: 10.1038/s41467-023-39824-4. Nat Commun. 2023. PMID: 37730687 Free PMC article.
Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality.
Molinaro A, Nemet I, Bel Lassen P, Chakaroun R, Nielsen T, Aron-Wisnewsky J, Bergh PO, Li L, Henricsson M, Køber L, Isnard R, Helft G, Stumvoll M, Pedersen O, Smith JG, Tang WHW, Clément K, Hazen SL, Bäckhed F; MetaCardis Consortium. Molinaro A, et al. JACC Heart Fail. 2023 Jul;11(7):810-821. doi: 10.1016/j.jchf.2023.03.008. Epub 2023 Apr 26. JACC Heart Fail. 2023. PMID: 37115134 Free article.

Elevated ImP was a significant independent predictor of 5-year mortality (for the highest quartile, adjusted HR: 1.85 [95% CI: 1.20-2.88]; P < 0.01). CONCLUSIONS: The gut microbial metabolite ImP is increased in individuals with heart failure and is a predictor of overa

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Elevated ImP was a significant independent predictor of 5-year mortality (for the highest quartile, adjusted HR: 1.85 [95% CI: 1.20-2.88]; …
Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial.
Bagshaw SM, Neto AS, Smith O, Weir M, Qiu H, Du B, Wang AY, Gallagher M, Bellomo R, Wald R; STARRT-AKI Investigators. Bagshaw SM, et al. Intensive Care Med. 2022 Dec;48(12):1736-1750. doi: 10.1007/s00134-022-06912-w. Epub 2022 Nov 4. Intensive Care Med. 2022. PMID: 36331570 Clinical Trial.

Patients with CKD were older and more likely to have cardiovascular comorbidities and diabetes mellitus. Patients with CKD had higher 90-day mortality (47% vs. 40%, p < 0.001) compared to those without CKD, though this was not significant after covariate adjustment (adj

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Patients with CKD were older and more likely to have cardiovascular comorbidities and diabetes mellitus. Patients with CKD had higher 90-day …
Prognostic value of longitudinal strain and ejection fraction in Friedreich's ataxia.
Legrand L, Heuze C, Diallo A, Monin ML, Ewenczyk C, Vicaut E, Montalescot G, Isnard R, Durr A, Pousset F. Legrand L, et al. Int J Cardiol. 2021 May 1;330:259-265. doi: 10.1016/j.ijcard.2021.02.032. Epub 2021 Feb 14. Int J Cardiol. 2021. PMID: 33592237 Free article.

In univariate Cox analysis, all-cause mortality was associated with: LS (HR 0.83; 95%CI, 0.75-0.91, p = 0.0002), LVEF (HR 0.30; 95%CI, 0.19-0.49, p < 0.0001), GAA repeats on the shorter allele (HR 1.29; 95%CI, 1.10-1.51, p = 0.002), age at onset (HR 0.87;

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In univariate Cox analysis, all-cause mortality was associated with: LS (HR 0.83; 95%CI, 0.75-0.91, p = 0.0002), LVEF (HR 0.30; 95%CI …
Antithrombotic Therapy for Patients With Left Ventricular Mural Thrombus.
Lattuca B, Bouziri N, Kerneis M, Portal JJ, Zhou J, Hauguel-Moreau M, Mameri A, Zeitouni M, Guedeney P, Hammoudi N, Isnard R, Pousset F, Collet JP, Vicaut E, Montalescot G, Silvain J; ACTION Study Group. Lattuca B, et al. J Am Coll Cardiol. 2020 Apr 14;75(14):1676-1685. doi: 10.1016/j.jacc.2020.01.057. J Am Coll Cardiol. 2020. PMID: 32273033 Free article.
The independent correlates of LVT regression were a nonischemic cardiomyopathy (hazard ratio [HR]: 2.74; 95% confidence interval [CI]: 1.43 to 5.26; p = 0.002) and a smaller baseline thrombus area (HR: 0.66; 95% CI: 0.45 to 0.96; p = 0.031). ...A left ventricular ej …
The independent correlates of LVT regression were a nonischemic cardiomyopathy (hazard ratio [HR]: 2.74; 95% confidence interval [CI]: 1.43 …
Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.
Vaara ST, Serpa Neto A, Bellomo R, Adhikari NKJ, Dreyfuss D, Gallagher M, Gaudry S, Hoste E, Joannidis M, Pettilä V, Wang AY, Kashani K, Wald R, Bagshaw SM, Ostermann M; STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Investigators. Vaara ST, et al. Crit Care Explor. 2024 Feb 19;6(2):e1053. doi: 10.1097/CCE.0000000000001053. eCollection 2024 Feb. Crit Care Explor. 2024. PMID: 38380940 Free PMC article.

MEASUREMENTS AND MAIN RESULTS: Total mean FB to a maximum of 14 days was +7199 mL in North America, +5641 mL in Europe, and +2211 mL in ANZ (p < 0.001). The median time to RRT initiation among patients allocated to the standard strategy was longest in Europe compared wi

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MEASUREMENTS AND MAIN RESULTS: Total mean FB to a maximum of 14 days was +7199 mL in North America, +5641 mL in Europe, and +2211 mL in ANZ …
Safety and efficacy of leriglitazone for preventing disease progression in men with adrenomyeloneuropathy (ADVANCE): a randomised, double-blind, multi-centre, placebo-controlled phase 2-3 trial.
Köhler W, Engelen M, Eichler F, Lachmann R, Fatemi A, Sampson J, Salsano E, Gamez J, Molnar MJ, Pascual S, Rovira M, Vilà A, Pina G, Martín-Ugarte I, Mantilla A, Pizcueta P, Rodríguez-Pascau L, Traver E, Vilalta A, Pascual M, Martinell M, Meya U, Mochel F; ADVANCE Study Group. Köhler W, et al. Lancet Neurol. 2023 Feb;22(2):127-136. doi: 10.1016/S1474-4422(22)00495-1. Lancet Neurol. 2023. PMID: 36681445 Clinical Trial.
There was no between-group difference in the primary endpoint (mean [SD] change from baseline leriglitazone: -27.7 [41.4] m; placebo: -30.3 [60.5] m; least-squares mean difference -1.2 m; 95% CI -22.6 to 20.2; p=0.91). The most common treatment emergent adverse events in b …
There was no between-group difference in the primary endpoint (mean [SD] change from baseline leriglitazone: -27.7 [41.4] m; placebo: -30.3 …
Significance of NT-proBNP and High-sensitivity Troponin in Friedreich Ataxia.
Legrand L, Maupain C, Monin ML, Ewenczyk C, Isnard R, Alkouri R, Durr A, Pousset F. Legrand L, et al. J Clin Med. 2020 May 28;9(6):1630. doi: 10.3390/jcm9061630. J Clin Med. 2020. PMID: 32481586 Free PMC article.

Increased septal wall thickness was associated with increased hsTnT plasma levels (p < 0.001). The median NT-proBNP concentration was 31 ng/L (5 to 775 ng/L) and 14% had significant elevated NT-proBNP 125 ng/L. Markers of increased left ventricular filling pressure (tra

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Increased septal wall thickness was associated with increased hsTnT plasma levels (p < 0.001). The median NT-proBNP concentration

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Heart rate per se impacts cardiac function in patients with systolic heart failure and pacing: a pilot study.
Logeart D, Gueffet JP, Rouzet F, Pousset F, Chavelas C, Solal AC, Jondeau G. Logeart D, et al. Eur J Heart Fail. 2009 Jan;11(1):53-7. doi: 10.1093/eurjhf/hfn016. Eur J Heart Fail. 2009. PMID: 19147457 Free article. Clinical Trial.
AIMS: This study was designed to compare the specific effects of two heart rates (HR), 55 and 75 b.p.m., in patients with heart failure (HF). METHODS AND RESULTS: Patients with chronic HF, left ventricular ejection fraction (LVEF) </= 35%, and a pacemaker with >90% o …
AIMS: This study was designed to compare the specific effects of two heart rates (HR), 55 and 75 b.p.m., in patients with heart failu …
45 results