Smith RG - Search Results

1

Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.

Nargund RP, Patchett AA, Bach MA, Murphy MG, Smith RG. Nargund RP, et al. Among authors: smith rg. J Med Chem. 1998 Aug 13;41(17):3103-27. doi: 10.1021/jm970342o. J Med Chem. 1998. PMID: 9703459 Review. No abstract available.

2

Thiazole-derived potent, highly bioavailable short duration growth hormone secretagogues.

Yang L, Morriello G, Leung K, Jacks T, Cheng K, Schleim KD, Smith R, Patchett AA. Yang L, et al. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1761-6. doi: 10.1016/s0960-894x(99)00286-3. Bioorg Med Chem Lett. 1999. PMID: 10406638

3

Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.

Dean DC, Nargund RP, Pong SS, Chaung LY, Griffin P, Melillo DG, Ellsworth RL, Van der Ploeg LH, Patchett AA, Smith RG. Dean DC, et al. Among authors: smith rg. J Med Chem. 1996 Apr 26;39(9):1767-70. doi: 10.1021/jm960054c. J Med Chem. 1996. PMID: 8627599 No abstract available.

4

Identification of a new G-protein-linked receptor for growth hormone secretagogues.

Pong SS, Chaung LY, Dean DC, Nargund RP, Patchett AA, Smith RG. Pong SS, et al. Among authors: smith rg. Mol Endocrinol. 1996 Jan;10(1):57-61. doi: 10.1210/mend.10.1.8838145. Mol Endocrinol. 1996. PMID: 8838145

5

Peptidomimetic regulation of growth hormone secretion.

Smith RG, Van der Ploeg LH, Howard AD, Feighner SD, Cheng K, Hickey GJ, Wyvratt MJ Jr, Fisher MH, Nargund RP, Patchett AA. Smith RG, et al. Endocr Rev. 1997 Oct;18(5):621-45. doi: 10.1210/edrv.18.5.0316. Endocr Rev. 1997. PMID: 9331545 Review. No abstract available.

6

Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.

Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, Underwood D, Tata JR, Dean DC, Tan CP, McKee KK, Woods JW, Patchett AA, Smith RG, Van der Ploeg LH. Feighner SD, et al. Among authors: smith rg. Mol Endocrinol. 1998 Jan;12(1):137-45. doi: 10.1210/mend.12.1.0051. Mol Endocrinol. 1998. PMID: 9440817

7

1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]- 3-benzylpiperidine-3(S)-carboxylic acid ethyl ester (L-163,540): a potent, orally bioavailable, and short-duration growth hormone secretagogue.

Yang L, Morriello G, Patchett AA, Leung K, Jacks T, Cheng K, Schleim KD, Feeney W, Chan WW, Chiu SH, Smith RG. Yang L, et al. Among authors: smith rg. J Med Chem. 1998 Jul 2;41(14):2439-41. doi: 10.1021/jm9800191. J Med Chem. 1998. PMID: 9651148 No abstract available.

8

Orally active growth hormone secretagogues.

Patchett AA, Smith RG, Wyvratt MJ. Patchett AA, et al. Among authors: smith rg. Pharm Biotechnol. 1998;11:525-54. doi: 10.1007/0-306-47384-4_23. Pharm Biotechnol. 1998. PMID: 9760695 Review. No abstract available.

9

Tripeptide growth hormone secretagogues.

Yang L, Morriello G, Pan Y, Nargund RP, Barakat K, Prendergast K, Cheng K, Chan WW, Smith RG, Patchett AA. Yang L, et al. Among authors: smith rg. Bioorg Med Chem Lett. 1998 Apr 7;8(7):759-64. doi: 10.1016/s0960-894x(98)00103-6. Bioorg Med Chem Lett. 1998. PMID: 9871537

10

Synthesis and biological activities of phenyl piperazine-based peptidomimetic growth hormone secretagogues.

Barakat KJ, Cheng K, Chan WW, Butler BS, Jacks TM, Schleim KD, Hora DF Jr, Hickey GJ, Smith RG, Patchett AA, Nargund RP. Barakat KJ, et al. Among authors: smith rg. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1431-6. doi: 10.1016/s0960-894x(98)00238-8. Bioorg Med Chem Lett. 1998. PMID: 9871779

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