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RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist.
Bonhaus DW, Weinhardt KK, Taylor M, DeSouza A, McNeeley PM, Szczepanski K, Fontana DJ, Trinh J, Rocha CL, Dawson MW, Flippin LA, Eglen RM. Bonhaus DW, et al. Among authors: rocha cl. Neuropharmacology. 1997 Apr-May;36(4-5):621-9. doi: 10.1016/s0028-3908(97)00049-x. Neuropharmacology. 1997. PMID: 9225287
Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.
Alig L, Alsenz J, Andjelkovic M, Bendels S, Bénardeau A, Bleicher K, Bourson A, David-Pierson P, Guba W, Hildbrand S, Kube D, Lübbers T, Mayweg AV, Narquizian R, Neidhart W, Nettekoven M, Plancher JM, Rocha C, Rogers-Evans M, Röver S, Schneider G, Taylor S, Waldmeier P. Alig L, et al. J Med Chem. 2008 Apr 10;51(7):2115-27. doi: 10.1021/jm701487t. Epub 2008 Mar 13. J Med Chem. 2008. PMID: 18335976
Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
Crosignani S, Page P, Missotten M, Colovray V, Cleva C, Arrighi JF, Atherall J, Macritchie J, Martin T, Humbert Y, Gaudet M, Pupowicz D, Maio M, Pittet PA, Golzio L, Giachetti C, Rocha C, Bernardinelli G, Filinchuk Y, Scheer A, Schwarz MK, Chollet A. Crosignani S, et al. J Med Chem. 2008 Apr 10;51(7):2227-43. doi: 10.1021/jm701383e. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318469
Chiral kinetics and dynamics of ketorolac.
Mroszczak E, Combs D, Chaplin M, Tsina I, Tarnowski T, Rocha C, Tam Y, Boyd A, Young J, Depass L. Mroszczak E, et al. J Clin Pharmacol. 1996 Jun;36(6):521-39. doi: 10.1002/j.1552-4604.1996.tb05042.x. J Clin Pharmacol. 1996. PMID: 8809637
42 results