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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice.
Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George Hyslop P, Selkoe DJ. Citron M, et al. Among authors: yao h. Nat Med. 1997 Jan;3(1):67-72. doi: 10.1038/nm0197-67. Nat Med. 1997. PMID: 8986743
PFKFB3 controls acinar IP3R-mediated Ca2+ overload to regulate acute pancreatitis severity.
Zhang T, Chen S, Li L, Jin Y, Liu S, Liu Z, Shi F, Xie L, Guo P, Cannon AC, Ergashev A, Yao H, Huang C, Zhang B, Wu L, Sun H, Chen S, Shan Y, Yu Z, Tolosa EJ, Liu J, Fernandez-Zapico ME, Ma F, Chen G. Zhang T, et al. Among authors: yao h. JCI Insight. 2024 May 23:e169481. doi: 10.1172/jci.insight.169481. Online ahead of print. JCI Insight. 2024. PMID: 38781030
Drug screening on digital microfluidics for cancer precision medicine.
Zhai J, Liu Y, Ji W, Huang X, Wang P, Li Y, Li H, Wong AH, Zhou X, Chen P, Wang L, Yang N, Chen C, Chen H, Mak PI, Deng CX, Martins R, Yang M, Ho TY, Yi S, Yao H, Jia Y. Zhai J, et al. Among authors: yao h. Nat Commun. 2024 May 22;15(1):4363. doi: 10.1038/s41467-024-48616-3. Nat Commun. 2024. PMID: 38778087
7,586 results