Seydel JK - Search Results

1

Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.

Otzen T, Wempe EG, Kunz B, Bartels R, Lehwark-Yvetot G, Hänsel W, Schaper KJ, Seydel JK. Otzen T, et al. Among authors: seydel jk. J Med Chem. 2004 Jan 1;47(1):240-53. doi: 10.1021/jm030931w. J Med Chem. 2004. PMID: 14695838

2

Studies on the toxicity and efficacy of some ester analogues of dapsone in vitro using rat and human tissues.

Coleman MD, Hadley S, Perris AD, Jorga K, Seydel JK. Coleman MD, et al. Among authors: seydel jk. Environ Toxicol Pharmacol. 2002 Aug;12(1):7-13. doi: 10.1016/s1382-6689(01)00123-5. Environ Toxicol Pharmacol. 2002. PMID: 21782618

3

Partial resistance of E. coli mutants against 2, 4-diamino-5-benzylpyrimidines by interactions with bacterial membrane lipopolysaccharides. Derivation of quantitative structure-binding relationships.

Schop H, Wiese M, Cordes HP, Seydel JK. Schop H, et al. Among authors: seydel jk. Eur J Med Chem. 2000 Jun;35(6):619-34. doi: 10.1016/s0223-5234(00)00159-8. Eur J Med Chem. 2000. PMID: 10906413

4

Inhibition of the conjugation of PABA with glycine in vitro by sulfamoyl benzoic acids, sulfonamides, and penicillins and its relation to tubular secretion.

Ehlert C, Strunz H, Visser K, Wiese M, Seydel JK. Ehlert C, et al. Among authors: seydel jk. J Pharm Sci. 1998 Jun;87(6):785. doi: 10.1021/js9801539. J Pharm Sci. 1998. PMID: 9607961 No abstract available.

5

Inhibition of the conjugation of PABA with glycine in vitro by sulfamoyl benzoic acids, sulfonamides, and penicillins and its relation to tubular secretion.

Ehlert C, Strunz H, Visser K, Wiese M, Seydel JK. Ehlert C, et al. Among authors: seydel jk. J Pharm Sci. 1998 Jan;87(1):101-8. doi: 10.1021/js9700917. J Pharm Sci. 1998. PMID: 9452977

6

Studies on the inhibitory effects of analogues of dapsone on neutrophil function in-vitro.

Coleman MD, Smith JK, Perris AD, Buck NS, Seydel JK. Coleman MD, et al. Among authors: seydel jk. J Pharm Pharmacol. 1997 Jan;49(1):53-7. doi: 10.1111/j.2042-7158.1997.tb06752.x. J Pharm Pharmacol. 1997. PMID: 9120771

7

Preliminary evaluation of the toxicity and efficacy of novel 2,4-diamino-5-benzylpyrimidine-sulphone derivatives using rat and human tissues in vitro.

Coleman MD, Thorpe S, Lewis S, Buck NS, Perris AD, Seydel JK. Coleman MD, et al. Among authors: seydel jk. Environ Toxicol Pharmacol. 1996 Dec 20;2(4):389-95. doi: 10.1016/s1382-6689(96)00076-2. Environ Toxicol Pharmacol. 1996. PMID: 21781747

8

Structure-activity relationship studies on benzofuran analogs of propafenone-type modulators of tumor cell multidrug resistance.

Ecker G, Chiba P, Hitzler M, Schmid D, Visser K, Cordes HP, Csöllei J, Seydel JK, Schaper KJ. Ecker G, et al. Among authors: seydel jk. J Med Chem. 1996 Nov 22;39(24):4767-74. doi: 10.1021/jm960384x. J Med Chem. 1996. PMID: 8941391

9

Studies on the toxicity of analogues of dapsone in-vitro using rat, human and heterologously expressed metabolizing systems.

Coleman MD, Smith SN, Kelly DE, Kelly SL, Seydel JK. Coleman MD, et al. Among authors: seydel jk. J Pharm Pharmacol. 1996 Sep;48(9):945-50. doi: 10.1111/j.2042-7158.1996.tb06008.x. J Pharm Pharmacol. 1996. PMID: 8910859

10

Syntheses and biological activities of new N1-aryl substituted quinolone antibacterials.

Jürgens J, Schedletzky H, Heisig P, Seydel JK, Wiedemann B, Holzgrabe U. Jürgens J, et al. Among authors: seydel jk. Arch Pharm (Weinheim). 1996 Apr;329(4):179-90. doi: 10.1002/ardp.19963290403. Arch Pharm (Weinheim). 1996. PMID: 8669982

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