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Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo.
Murray J, Valli E, Yu DMT, Truong AM, Gifford AJ, Eden GL, Gamble LD, Hanssen KM, Flemming CL, Tan A, Tivnan A, Allan S, Saletta F, Cheung L, Ruhle M, Schuetz JD, Henderson MJ, Byrne JA, Norris MD, Haber M, Fletcher JI. Murray J, et al. Among authors: fletcher ji. Eur J Cancer. 2017 Sep;83:132-141. doi: 10.1016/j.ejca.2017.06.024. Epub 2017 Jul 20. Eur J Cancer. 2017. PMID: 28735070 Free PMC article.
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.
Gamble LD, Purgato S, Murray J, Xiao L, Yu DMT, Hanssen KM, Giorgi FM, Carter DR, Gifford AJ, Valli E, Milazzo G, Kamili A, Mayoh C, Liu B, Eden G, Sarraf S, Allan S, Di Giacomo S, Flemming CL, Russell AJ, Cheung BB, Oberthuer A, London WB, Fischer M, Trahair TN, Fletcher JI, Marshall GM, Ziegler DS, Hogarty MD, Burns MR, Perini G, Norris MD, Haber M. Gamble LD, et al. Among authors: fletcher ji. Sci Transl Med. 2019 Jan 30;11(477):eaau1099. doi: 10.1126/scitranslmed.aau1099. Sci Transl Med. 2019. PMID: 30700572
CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.
Huynh T, Murray J, Flemming CL, Kamili A, Hofmann U, Cheung L, Roundhill EA, Yu DMT, Webber HT, Schwab M, Henderson MJ, Haber M, Norris MD, Fletcher JI. Huynh T, et al. Among authors: fletcher ji. Biochem Pharmacol. 2020 Feb;172:113770. doi: 10.1016/j.bcp.2019.113770. Epub 2019 Dec 17. Biochem Pharmacol. 2020. PMID: 31862449
Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy.
Kamili A, Gifford AJ, Li N, Mayoh C, Chow SO, Failes TW, Eden GL, Cadiz R, Xie J, Lukeis RE, Norris MD, Haber M, McCowage GB, Arndt GM, Trahair TN, Fletcher JI. Kamili A, et al. Among authors: fletcher ji. Br J Cancer. 2020 Mar;122(5):680-691. doi: 10.1038/s41416-019-0682-4. Epub 2020 Jan 10. Br J Cancer. 2020. PMID: 31919402 Free PMC article.
Mouse models of high-risk neuroblastoma.
Kamili A, Atkinson C, Trahair TN, Fletcher JI. Kamili A, et al. Among authors: fletcher ji. Cancer Metastasis Rev. 2020 Mar;39(1):261-274. doi: 10.1007/s10555-020-09855-0. Cancer Metastasis Rev. 2020. PMID: 31989509 Review.
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.
Gao J, Jung M, Mayoh C, Venkat P, Hannan KM, Fletcher JI, Kamili A, Gifford AJ, Kusnadi EP, Pearson RB, Hannan RD, Haber M, Norris MD, Somers K, Henderson MJ. Gao J, et al. Among authors: fletcher ji. Cancer Res. 2020 Sep 1;80(17):3706-3718. doi: 10.1158/0008-5472.CAN-19-3914. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651259
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