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Page 1
Th2 Cells Are Associated with Tumor Recurrence Following Radiation.
Abdelhakiem MK, Bao R, Pifer PM, Molkentine D, Molkentine J, Hefner A, Beadle B, Heymach JV, Luke JJ, Ferris RL, Pickering CR, Wang JH, Patel RB, Skinner HD. Abdelhakiem MK, et al. Among authors: molkentine d. Cancers (Basel). 2024 Apr 20;16(8):1586. doi: 10.3390/cancers16081586. Cancers (Basel). 2024. PMID: 38672668 Free PMC article.
FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner.
Pifer PM, Yang L, Kumar M, Xie T, Frederick M, Hefner A, Beadle B, Molkentine D, Molkentine J, Dhawan A, Abdelhakiem M, Osman AA, Leibowitz BJ, Myers JN, Pickering CR, Sandulache VC, Heymach J, Skinner HD. Pifer PM, et al. Among authors: molkentine d. Clin Cancer Res. 2024 Jan 5;30(1):187-197. doi: 10.1158/1078-0432.CCR-23-0964. Clin Cancer Res. 2024. PMID: 37819945 Free PMC article.
ATM Mutations Associate with Distinct Co-Mutational Patterns and Therapeutic Vulnerabilities in NSCLC.
Vokes NI, Galan Cobo A, Fernandez-Chas M, Molkentine D, Treviño S 3rd, Druker V, Qian Y, Patel S, Schmidt S, Hong L, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee JJ, Negrao MV, Gibbons DL, Vaporciyan A, Le X, Wu J, Zhang J, Rigney U, Iyer S, Dean E, Heymach JV. Vokes NI, et al. Among authors: molkentine d. Clin Cancer Res. 2023 Dec 1;29(23):4958-4972. doi: 10.1158/1078-0432.CCR-23-1122. Clin Cancer Res. 2023. PMID: 37733794 Free PMC article.
MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
Qian Y, Galan-Cobo A, Guijarro I, Dang M, Molkentine D, Poteete A, Zhang F, Wang Q, Wang J, Parra E, Panda A, Fang J, Skoulidis F, Wistuba II, Verma S, Merghoub T, Wolchok JD, Wong KK, DeBerardinis RJ, Minna JD, Vokes NI, Meador CB, Gainor JF, Wang L, Reuben A, Heymach JV. Qian Y, et al. Among authors: molkentine d. Cancer Cell. 2023 Jul 10;41(7):1363-1380.e7. doi: 10.1016/j.ccell.2023.05.015. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327788
p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade.
Molkentine DP, Molkentine JM, Bridges KA, Valdecanas DR, Dhawan A, Bahri R, Hefner AJ, Kumar M, Yang L, Abdelhakiem M, Pifer PM, Sandulache V, Sheth A, Beadle BM, Thames HD, Mason KA, Pickering CR, Meyn RE, Skinner HD. Molkentine DP, et al. Cancer Res. 2022 Mar 1;82(5):916-928. doi: 10.1158/0008-5472.CAN-21-2101. Cancer Res. 2022. PMID: 34965932 Free PMC article.
Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.
Kumar M, Molkentine D, Molkentine J, Bridges K, Xie T, Yang L, Hefner A, Gao M, Bahri R, Dhawan A, Frederick MJ, Seth S, Abdelhakiem M, Beadle BM, Johnson F, Wang J, Shen L, Heffernan T, Sheth A, Ferris RL, Myers JN, Pickering CR, Skinner HD. Kumar M, et al. Among authors: molkentine d. Nat Commun. 2021 Nov 3;12(1):6340. doi: 10.1038/s41467-021-26570-8. Nat Commun. 2021. PMID: 34732714 Free PMC article.
Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints.
Molkentine JM, Molkentine DP, Bridges KA, Xie T, Yang L, Sheth A, Heffernan TP, Clump DA, Faust AZ, Ferris RL, Myers JN, Frederick MJ, Mason KA, Meyn RE, Pickering CR, Skinner HD. Molkentine JM, et al. Among authors: molkentine dp. Int J Radiat Biol. 2021;97(8):1121-1128. doi: 10.1080/09553002.2020.1730014. Epub 2020 Feb 25. Int J Radiat Biol. 2021. PMID: 32073931 Free PMC article.
Proton versus photon radiation-induced cell death in head and neck cancer cells.
Wang L, Han S, Zhu J, Wang X, Li Y, Wang Z, Lin E, Wang X, Molkentine DP, Blanchard P, Yang Y, Zhang R, Sahoo N, Gillin M, Zhu XR, Zhang X, Myers JN, Frank SJ. Wang L, et al. Among authors: molkentine dp. Head Neck. 2019 Jan;41(1):46-55. doi: 10.1002/hed.25357. Epub 2018 Dec 18. Head Neck. 2019. PMID: 30561022
BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer.
Liu X, Kumar M, Yang L, Molkentine DP, Valdecanas D, Yu S, Meyn RE, Heymach JV, Skinner HD. Liu X, et al. Among authors: molkentine dp. Clin Cancer Res. 2018 Feb 1;24(3):600-607. doi: 10.1158/1078-0432.CCR-17-1573. Epub 2017 Nov 7. Clin Cancer Res. 2018. PMID: 29113987 Free PMC article.
Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer.
Skinner HD, Giri U, Yang LP, Kumar M, Liu Y, Story MD, Pickering CR, Byers LA, Williams MD, Wang J, Shen L, Yoo SY, Fan YH, Molkentine DP, Beadle BM, Meyn RE, Myers JN, Heymach JV. Skinner HD, et al. Among authors: molkentine dp. Clin Cancer Res. 2017 Jun 1;23(11):2713-2722. doi: 10.1158/1078-0432.CCR-16-2586. Epub 2017 May 5. Clin Cancer Res. 2017. PMID: 28476872 Free PMC article.
25 results