Barreiro EJ - Search Results

1

Antiproliferative Activity of N-Acylhydrazone Derivative on Hepatocellular Carcinoma Cells Involves Transcriptional Regulation of Genes Required for G2/M Transition.

Andrade AAR, Pauli F, Pressete CG, Zavan B, Hanemann JAC, Miyazawa M, Fonseca R, Caixeta ES, Nacif JLM, Aissa AF, Barreiro EJ, Ionta M. Andrade AAR, et al. Among authors: barreiro ej. Biomedicines. 2024 Apr 18;12(4):892. doi: 10.3390/biomedicines12040892. Biomedicines. 2024. PMID: 38672246 Free PMC article.

2

Novel VEGFR-2 inhibitors with an N-acylhydrazone scaffold.

Pauli FP, Martins JR, Paschoalin T, Ionta M, Barbosa MLC, Barreiro EJ. Pauli FP, et al. Among authors: barreiro ej. Arch Pharm (Weinheim). 2020 Nov;353(11):e2000130. doi: 10.1002/ardp.202000130. Epub 2020 Jul 15. Arch Pharm (Weinheim). 2020. PMID: 32667721

3

Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile.

Pillpe-Meza RM, Gouveia WL, Barbosa G, Fraga CAM, Barreiro EJ, Lima LM. Pillpe-Meza RM, et al. Among authors: barreiro ej. Pharmaceuticals (Basel). 2024 Mar 18;17(3):389. doi: 10.3390/ph17030389. Pharmaceuticals (Basel). 2024. PMID: 38543175 Free PMC article.

4

Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative.

Bastos ITS, Pinheiro PSM, Costa FN, Rocha MD, Sant'Anna CMR, Braz D, Souza ET, Martins MA, Barreiro EJ, Ferreira FF, Barroso RC, Fraga CAM. Bastos ITS, et al. Among authors: barreiro ej. Pharmaceuticals (Basel). 2018 Nov 1;11(4):119. doi: 10.3390/ph11040119. Pharmaceuticals (Basel). 2018. PMID: 30388818 Free PMC article.

5

Synthesis and anti-platelet activity of novel arylsulfonate--acylhydrazone derivatives, designed as antithrombotic candidates.

Lima LM, Frattani FS, Dos Santos JL, Castro HC, Fraga CA, Zingali RB, Barreiro EJ. Lima LM, et al. Among authors: barreiro ej. Eur J Med Chem. 2008 Feb;43(2):348-56. doi: 10.1016/j.ejmech.2007.03.032. Epub 2007 Apr 14. Eur J Med Chem. 2008. PMID: 17532545

6

Effect of S-Se Bioisosteric Exchange on Affinity and Intrinsic Efficacy of Novel N-acylhydrazone Derivatives at the Adenosine A_2A Receptor.

Pedreira JGB, Silva RR, Noël FG, Barreiro EJ. Pedreira JGB, et al. Among authors: barreiro ej. Molecules. 2021 Dec 4;26(23):7364. doi: 10.3390/molecules26237364. Molecules. 2021. PMID: 34885946 Free PMC article.

7

Docking, synthesis and antiproliferative activity of N-acylhydrazone derivatives designed as combretastatin A4 analogues.

do Amaral DN, Cavalcanti BC, Bezerra DP, Ferreira PM, Castro Rde P, Sabino JR, Machado CM, Chammas R, Pessoa C, Sant'Anna CM, Barreiro EJ, Lima LM. do Amaral DN, et al. Among authors: barreiro ej. PLoS One. 2014 Mar 10;9(3):e85380. doi: 10.1371/journal.pone.0085380. eCollection 2014. PLoS One. 2014. PMID: 24614859 Free PMC article.

8

N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity.

Alencar AK, Pereira SL, da Silva FE, Mendes LV, Cunha Vdo M, Lima LM, Montagnoli TL, Caruso-Neves C, Ferraz EB, Tesch R, Nascimento JH, Sant'anna CM, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G. Alencar AK, et al. Among authors: barreiro ej. Int J Cardiol. 2014 May 1;173(2):154-62. doi: 10.1016/j.ijcard.2014.02.022. Epub 2014 Feb 24. Int J Cardiol. 2014. PMID: 24630383

9

Discovery of naphthyl-N-acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity.

Freitas RHCN, Cordeiro NM, Carvalho PR, Alves MA, Guedes IA, Valerio TS, Dardenne LE, Lima LM, Barreiro EJ, Fernandes PD, Fraga CAM. Freitas RHCN, et al. Among authors: barreiro ej. Chem Biol Drug Des. 2018 Feb;91(2):391-397. doi: 10.1111/cbdd.13085. Epub 2017 Sep 10. Chem Biol Drug Des. 2018. PMID: 28815968

10

Potent immunosuppressive activity of a phosphodiesterase-4 inhibitor N-acylhydrazone in models of lipopolysaccharide-induced shock and delayed-type hypersensitivity reaction.

Guimarães ET, Dos Santos TB, Silva DKC, Meira CS, Moreira DRM, da Silva TF, Salmon D, Barreiro EJ, Soares MBP. Guimarães ET, et al. Among authors: barreiro ej. Int Immunopharmacol. 2018 Dec;65:108-118. doi: 10.1016/j.intimp.2018.09.047. Epub 2018 Oct 9. Int Immunopharmacol. 2018. PMID: 30312879

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