Welsch S - Search Results

1

Thinner is not always better: Optimizing cryo-lamellae for subtomogram averaging.

Tuijtel MW, Cruz-León S, Kreysing JP, Welsch S, Hummer G, Beck M, Turoňová B. Tuijtel MW, et al. Among authors: welsch s. Sci Adv. 2024 Apr 26;10(17):eadk6285. doi: 10.1126/sciadv.adk6285. Epub 2024 Apr 26. Sci Adv. 2024. PMID: 38669330 Free PMC article.

2

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.

Turoňová B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, von Bülow S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Landry J, de Azevedo NTD, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M. Turoňová B, et al. Among authors: welsch s. Science. 2020 Oct 9;370(6513):203-208. doi: 10.1126/science.abd5223. Epub 2020 Aug 18. Science. 2020. PMID: 32817270 Free PMC article.

3

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.

Safarian S, Opel-Reading HK, Wu D, Mehdipour AR, Hards K, Harold LK, Radloff M, Stewart I, Welsch S, Hummer G, Cook GM, Krause KL, Michel H. Safarian S, et al. Among authors: welsch s. Nat Commun. 2021 Sep 2;12(1):5236. doi: 10.1038/s41467-021-25537-z. Nat Commun. 2021. PMID: 34475399 Free PMC article.

4

Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism.

Khera R, Mehdipour AR, Bolla JR, Kahnt J, Welsch S, Ermler U, Muenke C, Robinson CV, Hummer G, Xie H, Michel H. Khera R, et al. Among authors: welsch s. EMBO J. 2022 Sep 15;41(18):e109990. doi: 10.15252/embj.2021109990. Epub 2022 Jun 14. EMBO J. 2022. PMID: 35698912 Free PMC article.

5

Structures of the eukaryotic ribosome and its translational states in situ.

Hoffmann PC, Kreysing JP, Khusainov I, Tuijtel MW, Welsch S, Beck M. Hoffmann PC, et al. Among authors: welsch s. Nat Commun. 2022 Dec 2;13(1):7435. doi: 10.1038/s41467-022-34997-w. Nat Commun. 2022. PMID: 36460643 Free PMC article.

6

Dissecting the conformational complexity and mechanism of a bacterial heme transporter.

Wu D, Mehdipour AR, Finke F, Goojani HG, Groh RR, Grund TN, Reichhart TMB, Zimmermann R, Welsch S, Bald D, Shepherd M, Hummer G, Safarian S. Wu D, et al. Among authors: welsch s. Nat Chem Biol. 2023 Aug;19(8):992-1003. doi: 10.1038/s41589-023-01314-5. Epub 2023 Apr 24. Nat Chem Biol. 2023. PMID: 37095238 Free PMC article.

7

Translation dynamics in human cells visualized at high resolution reveal cancer drug action.

Xing H, Taniguchi R, Khusainov I, Kreysing JP, Welsch S, Turoňová B, Beck M. Xing H, et al. Among authors: welsch s. Science. 2023 Jul 7;381(6653):70-75. doi: 10.1126/science.adh1411. Epub 2023 Jul 6. Science. 2023. PMID: 37410833

8

The palisade layer of the poxvirus core is composed of flexible A10 trimers.

Liu J, Corroyer-Dulmont S, Pražák V, Khusainov I, Bahrami K, Welsch S, Vasishtan D, Obarska-Kosińska A, Thorkelsson SR, Grünewald K, Quemin ERJ, Turoňová B, Locker JK. Liu J, et al. Among authors: welsch s. Nat Struct Mol Biol. 2024 Feb 5. doi: 10.1038/s41594-024-01218-5. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38316878

9

Molecular mechanism of choline and ethanolamine transport in humans.

Ri K, Weng TH, Claveras Cabezudo A, Jösting W, Zhang Y, Bazzone A, Leong NCP, Welsch S, Doty RT, Gursu G, Lim TJY, Schmidt SL, Abkowitz JL, Hummer G, Wu D, Nguyen LN, Safarian S. Ri K, et al. Among authors: welsch s. Nature. 2024 May 22. doi: 10.1038/s41586-024-07444-7. Online ahead of print. Nature. 2024. PMID: 38778100

10

Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase.

Kolbe F, Safarian S, Piórek Ż, Welsch S, Müller H, Michel H. Kolbe F, et al. Among authors: welsch s. Nat Commun. 2021 Nov 25;12(1):6903. doi: 10.1038/s41467-021-27174-y. Nat Commun. 2021. PMID: 34824221 Free PMC article.

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