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Minimizing higher-order aggregation maximizes iron mobilization by small molecules.
Nat Chem Biol. 2024 Apr 25. doi: 10.1038/s41589-024-01596-3. Online ahead of print.
Nat Chem Biol. 2024.
PMID: 38664586
Distal structural elements coordinate a conserved base flipping network.
Matje DM, Krivacic CT, Dahlquist FW, Reich NO.
Matje DM, et al.
Biochemistry. 2013 Mar 12;52(10):1669-76. doi: 10.1021/bi301284f. Epub 2013 Feb 27.
Biochemistry. 2013.
PMID: 23409802
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Enzyme-promoted base flipping controls DNA methylation fidelity.
Matje DM, Zhou H, Smith DA, Neely RK, Dryden DT, Jones AC, Dahlquist FW, Reich NO.
Matje DM, et al.
Biochemistry. 2013 Mar 12;52(10):1677-85. doi: 10.1021/bi3012912. Epub 2013 Feb 27.
Biochemistry. 2013.
PMID: 23409782
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Molecular drivers of base flipping during sequence-specific DNA methylation.
Matje DM, Reich NO.
Matje DM, et al.
Chembiochem. 2012 Jul 23;13(11):1574-7. doi: 10.1002/cbic.201200104. Epub 2012 Jun 22.
Chembiochem. 2012.
PMID: 22730226
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Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation.
Holz-Schietinger C, Matje DM, Reich NO.
Holz-Schietinger C, et al. Among authors: matje dm.
J Biol Chem. 2012 Sep 7;287(37):30941-51. doi: 10.1074/jbc.M112.366625. Epub 2012 Jun 21.
J Biol Chem. 2012.
PMID: 22722925
Free PMC article.
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Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation.
Holz-Schietinger C, Matje DM, Harrison MF, Reich NO.
Holz-Schietinger C, et al. Among authors: matje dm.
J Biol Chem. 2011 Dec 2;286(48):41479-41488. doi: 10.1074/jbc.M111.284687. Epub 2011 Oct 6.
J Biol Chem. 2011.
PMID: 21979949
Free PMC article.
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Determinants of precatalytic conformational transitions in the DNA cytosine methyltransferase M.HhaI.
Matje DM, Coughlin DF, Connolly BA, Dahlquist FW, Reich NO.
Matje DM, et al.
Biochemistry. 2011 Mar 8;50(9):1465-73. doi: 10.1021/bi101446g. Epub 2011 Feb 10.
Biochemistry. 2011.
PMID: 21229971
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