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Re-discovery of MS-347a as a fungicide candidate through a new drug discovery platform with a multidrug-sensitive Saccharomyces cerevisiae screening system and the introduction of a global secondary metabolism regulator, laeA gene.
Honma S, Kimishima A, Kimishima A, Honsho M, Kojima H, Tokiwa T, Nishitomi A, Kato S, Kondo N, Araki Y, Takahashi T, Chinen T, Usui T, Fuji SI, Ito K, Asami Y. Honma S, et al. Among authors: kimishima a. Biosci Biotechnol Biochem. 2024 Apr 25:zbae050. doi: 10.1093/bbb/zbae050. Online ahead of print. Biosci Biotechnol Biochem. 2024. PMID: 38664007
A Combination Strategy of Multidrug-Sensitive Budding Yeast and Chemical Modifications Enabling to Find a New Overlooked Antifungal Compound, Sakurafusariene, from In-House Fractionated Library.
Kimishima A, Ono Y, Sakai K, Sakai K, Honsho M, Naher K, Tokiwa T, Kojima H, Higo M, Nonaka K, Iwatsuki M, Fuji SI, Chinen T, Usui T, Asami Y. Kimishima A, et al. J Agric Food Chem. 2023 Feb 14. doi: 10.1021/acs.jafc.2c09015. Online ahead of print. J Agric Food Chem. 2023. PMID: 36786603
Binding Mode-Based Physicochemical Screening Method Using d-Ala-d-Ala Silica Gel and Chemical Modification Approach to Facilitate Discovery of New Macrolactams, Banglactams A and B, from Nonomuraea bangladeshensis K18-0086.
Kimishima A, Suzuki Y, Kosaka S, Honsho M, Honma S, Tsutsumi H, Inahashi Y, Watanabe Y, Nakashima T, Asami Y, Iwatsuki M. Kimishima A, et al. ACS Omega. 2024 Apr 5;9(15):17415-17422. doi: 10.1021/acsomega.4c00145. eCollection 2024 Apr 16. ACS Omega. 2024. PMID: 38645345 Free PMC article.
Re-evaluation and a Structure-Activity Relationship Study for the Selective Anti-anaerobic Bacterial Activity of Luminamicin toward Target Identification.
Kimishima A, Negami S, Tsuruoka I, Tsutsumi H, Matsui H, Sugamata M, Kondo N, Honsho M, Sakai K, Honma S, Naher K, Watanabe Y, Iwatsuki M, Inahashi Y, Hanaki H, Asami Y. Kimishima A, et al. ACS Infect Dis. 2023 Aug 11;9(8):1602-1609. doi: 10.1021/acsinfecdis.3c00173. Epub 2023 Jul 7. ACS Infect Dis. 2023. PMID: 37418000
47 results