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Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.
Hosseinzadeh P, Watson PR, Craven TW, Li X, Rettie S, Pardo-Avila F, Bera AK, Mulligan VK, Lu P, Ford AS, Weitzner BD, Stewart LJ, Moyer AP, Di Piazza M, Whalen JG, Greisen PJ, Christianson DW, Baker D. Hosseinzadeh P, et al. Among authors: moyer ap. Nat Commun. 2021 Jun 7;12(1):3384. doi: 10.1038/s41467-021-23609-8. Nat Commun. 2021. PMID: 34099674 Free PMC article.
Stapled β-Hairpins Featuring 4-Mercaptoproline.
Pace JR, Lampkin BJ, Abakah C, Moyer A, Miao J, Deprey K, Cerulli RA, Lin YS, Baleja JD, Baker D, Kritzer JA. Pace JR, et al. J Am Chem Soc. 2021 Sep 22;143(37):15039-15044. doi: 10.1021/jacs.1c04378. Epub 2021 Sep 13. J Am Chem Soc. 2021. PMID: 34516087 Free PMC article.
Computational design of mechanically coupled axle-rotor protein assemblies.
Courbet A, Hansen J, Hsia Y, Bethel N, Park YJ, Xu C, Moyer A, Boyken SE, Ueda G, Nattermann U, Nagarajan D, Silva DA, Sheffler W, Quispe J, Nord A, King N, Bradley P, Veesler D, Kollman J, Baker D. Courbet A, et al. Science. 2022 Apr 22;376(6591):383-390. doi: 10.1126/science.abm1183. Epub 2022 Apr 21. Science. 2022. PMID: 35446645 Free PMC article.
De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs.
Ennist N, Wang S, Kennedy M, Curti M, Sutherland G, Vasilev C, Redler R, Maffeis V, Shareef S, Sica A, Hua A, Deshmukh A, Moyer A, Hicks D, Swartz A, Cacho R, Novy N, Bera A, Kang A, Sankaran B, Johnson M, Reppert M, Ekiert D, Bhabha G, Stewart L, Caram J, Stoddard B, Romero E, Hunter CN, Baker D. Ennist N, et al. Res Sq [Preprint]. 2023 Apr 21:rs.3.rs-2736786. doi: 10.21203/rs.3.rs-2736786/v1. Res Sq. 2023. PMID: 37131790 Free PMC article. Preprint.
De novo design of immunoglobulin-like domains.
Chidyausiku TM, Mendes SR, Klima JC, Nadal M, Eckhard U, Roel-Touris J, Houliston S, Guevara T, Haddox HK, Moyer A, Arrowsmith CH, Gomis-Rüth FX, Baker D, Marcos E. Chidyausiku TM, et al. Nat Commun. 2022 Oct 3;13(1):5661. doi: 10.1038/s41467-022-33004-6. Nat Commun. 2022. PMID: 36192397 Free PMC article.
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Ueda G, Antanasijevic A, Fallas JA, Sheffler W, Copps J, Ellis D, Hutchinson GB, Moyer A, Yasmeen A, Tsybovsky Y, Park YJ, Bick MJ, Sankaran B, Gillespie RA, Brouwer PJ, Zwart PH, Veesler D, Kanekiyo M, Graham BS, Sanders RW, Moore JP, Klasse PJ, Ward AB, King NP, Baker D. Ueda G, et al. Elife. 2020 Aug 4;9:e57659. doi: 10.7554/eLife.57659. Elife. 2020. PMID: 32748788 Free PMC article.