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PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Tran DHN, Agrawal A, Ghita L, Ojha A, East MP, Gammeltoft KA, Sahoo MK, Johnson GL, Das S, Jochmans D, Cohen CA, Gottwein J, Dye J, Neff N, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, Jonghe S, Asquith CRM, Einav S. Karim M, et al. Among authors: asquith crm. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589676. doi: 10.1101/2024.04.15.589676. bioRxiv. 2024. PMID: 38659941 Free PMC article. Preprint.
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies.
Karim M, Saul S, Ghita L, Sahoo MK, Ye C, Bhalla N, Lo CW, Jin J, Park JG, Martinez-Gualda B, East MP, Johnson GL, Pinsky BA, Martinez-Sobrido L, Asquith CRM, Narayanan A, De Jonghe S, Einav S. Karim M, et al. Among authors: asquith crm. Antiviral Res. 2022 Aug;204:105367. doi: 10.1016/j.antiviral.2022.105367. Epub 2022 Jun 20. Antiviral Res. 2022. PMID: 35738348 Free PMC article.
PKMYT1: a forgotten member of the WEE1 family.
Asquith CRM, Laitinen T, East MP. Asquith CRM, et al. Nat Rev Drug Discov. 2020 Mar;19(3):157. doi: 10.1038/d41573-019-00202-9. Nat Rev Drug Discov. 2020. PMID: 32127662 No abstract available.
WNK kinases: an untapped opportunity to modulate ion transport.
East MP, Laitinen T, Asquith CRM. East MP, et al. Among authors: asquith crm. Nat Rev Drug Discov. 2020 Dec;19(12):828. doi: 10.1038/d41573-020-00196-9. Nat Rev Drug Discov. 2020. PMID: 33159187 No abstract available.
51 results