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Multi-Omics after O-GlcNAc Alteration Identifies Cellular Processes Working Synergistically to Promote Aneuploidy.
Boyd SS, Robarts DR, Nguyen K, Villar M, Alghusen I, Kotulkar M, Denson A, Fedosyuk H, Whelan SA, Lee NCY, Hanover J, Dias WB, Tan EP, McGreal SR, Artigues A, Swerdlow RH, Thompson JA, Apte U, Slawson C. Boyd SS, et al. Among authors: mcgreal sr. bioRxiv [Preprint]. 2024 Apr 16:2024.04.16.589379. doi: 10.1101/2024.04.16.589379. bioRxiv. 2024. PMID: 38659829 Free PMC article. Preprint.
O-GlcNAc cycling mediates energy balance by regulating caloric memory.
Andersson B, Tan EP, McGreal SR, Apte U, Hanover JA, Slawson C, Lagerlöf O. Andersson B, et al. Among authors: mcgreal sr. Appetite. 2021 Oct 1;165:105320. doi: 10.1016/j.appet.2021.105320. Epub 2021 May 23. Appetite. 2021. PMID: 34029673 Free article.
Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice.
Robarts DR, McGreal SR, Umbaugh DS, Parkes WS, Kotulkar M, Abernathy S, Lee N, Jaeschke H, Gunewardena S, Whelan SA, Hanover JA, Zachara NE, Slawson C, Apte U. Robarts DR, et al. Among authors: mcgreal sr. Cell Mol Gastroenterol Hepatol. 2022;13(5):1510-1529. doi: 10.1016/j.jcmgh.2022.01.014. Epub 2022 Jan 28. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35093590 Free PMC article.
Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism.
Tan EP, McGreal SR, Graw S, Tessman R, Koppel SJ, Dhakal P, Zhang Z, Machacek M, Zachara NE, Koestler DC, Peterson KR, Thyfault JP, Swerdlow RH, Krishnamurthy P, DiTacchio L, Apte U, Slawson C. Tan EP, et al. Among authors: mcgreal sr. J Biol Chem. 2017 Sep 8;292(36):14940-14962. doi: 10.1074/jbc.M117.797944. Epub 2017 Jul 24. J Biol Chem. 2017. PMID: 28739801 Free PMC article.
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Bird TG, Müller M, Boulter L, Vincent DF, Ridgway RA, Lopez-Guadamillas E, Lu WY, Jamieson T, Govaere O, Campbell AD, Ferreira-Gonzalez S, Cole AM, Hay T, Simpson KJ, Clark W, Hedley A, Clarke M, Gentaz P, Nixon C, Bryce S, Kiourtis C, Sprangers J, Nibbs RJB, Van Rooijen N, Bartholin L, McGreal SR, Apte U, Barry ST, Iredale JP, Clarke AR, Serrano M, Roskams TA, Sansom OJ, Forbes SJ. Bird TG, et al. Among authors: mcgreal sr. Sci Transl Med. 2018 Aug 15;10(454):eaan1230. doi: 10.1126/scitranslmed.aan1230. Sci Transl Med. 2018. PMID: 30111642 Free PMC article.