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Periportal macrophages protect against commensal-driven liver inflammation.
Miyamoto Y, Kikuta J, Matsui T, Hasegawa T, Fujii K, Okuzaki D, Liu YC, Yoshioka T, Seno S, Motooka D, Uchida Y, Yamashita E, Kobayashi S, Eguchi H, Morii E, Tryggvason K, Shichita T, Kayama H, Atarashi K, Kunisawa J, Honda K, Takeda K, Ishii M. Miyamoto Y, et al. Among authors: kunisawa j. Nature. 2024 May;629(8013):901-909. doi: 10.1038/s41586-024-07372-6. Epub 2024 Apr 24. Nature. 2024. PMID: 38658756
Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine.
Kusu T, Kayama H, Kinoshita M, Jeon SG, Ueda Y, Goto Y, Okumura R, Saiga H, Kurakawa T, Ikeda K, Maeda Y, Nishimura J, Arima Y, Atarashi K, Honda K, Murakami M, Kunisawa J, Kiyono H, Okumura M, Yamamoto M, Takeda K. Kusu T, et al. Among authors: kunisawa j. J Immunol. 2013 Jan 15;190(2):774-83. doi: 10.4049/jimmunol.1103067. Epub 2012 Dec 14. J Immunol. 2013. PMID: 23241884 Free PMC article.
The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.
Nagatake T, Shiogama Y, Inoue A, Kikuta J, Honda T, Tiwari P, Kishi T, Yanagisawa A, Isobe Y, Matsumoto N, Shimojou M, Morimoto S, Suzuki H, Hirata SI, Steneberg P, Edlund H, Aoki J, Arita M, Kiyono H, Yasutomi Y, Ishii M, Kabashima K, Kunisawa J. Nagatake T, et al. Among authors: kunisawa j. J Allergy Clin Immunol. 2018 Aug;142(2):470-484.e12. doi: 10.1016/j.jaci.2017.09.053. Epub 2017 Dec 27. J Allergy Clin Immunol. 2018. PMID: 29288079 Free article.
Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome.
Takemura N, Kawasaki T, Kunisawa J, Sato S, Lamichhane A, Kobiyama K, Aoshi T, Ito J, Mizuguchi K, Karuppuchamy T, Matsunaga K, Miyatake S, Mori N, Tsujimura T, Satoh T, Kumagai Y, Kawai T, Standley DM, Ishii KJ, Kiyono H, Akira S, Uematsu S. Takemura N, et al. Among authors: kunisawa j. Nat Commun. 2014 Mar 18;5:3492. doi: 10.1038/ncomms4492. Nat Commun. 2014. PMID: 24637670 Free PMC article.
Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota.
Hosomi K, Saito M, Park J, Murakami H, Shibata N, Ando M, Nagatake T, Konishi K, Ohno H, Tanisawa K, Mohsen A, Chen YA, Kawashima H, Natsume-Kitatani Y, Oka Y, Shimizu H, Furuta M, Tojima Y, Sawane K, Saika A, Kondo S, Yonejima Y, Takeyama H, Matsutani A, Mizuguchi K, Miyachi M, Kunisawa J. Hosomi K, et al. Among authors: kunisawa j. Nat Commun. 2022 Aug 18;13(1):4477. doi: 10.1038/s41467-022-32015-7. Nat Commun. 2022. PMID: 35982037 Free PMC article.
199 results