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Reversible male contraception by targeted inhibition of serine/threonine kinase 33.
Ku AF, Sharma KL, Ta HM, Sutton CM, Bohren KM, Wang Y, Chamakuri S, Chen R, Hakenjos JM, Jimmidi R, Kent K, Li F, Li JY, Ma L, Madasu C, Palaniappan M, Palmer SS, Qin X, Robers MB, Sankaran B, Tan Z, Vasquez YM, Wang J, Wilkinson J, Yu Z, Ye Q, Young DW, Teng M, Kim C, Matzuk MM. Ku AF, et al. Among authors: hakenjos jm. Science. 2024 May 24;384(6698):885-890. doi: 10.1126/science.adl2688. Epub 2024 May 23. Science. 2024. PMID: 38781365
MALDI imaging mass spectrometry visualizes the distribution of antidepressant duloxetine and its major metabolites in mouse brain, liver, kidney, and spleen tissues.
Khalil SM, Qin X, Hakenjos JM, Wang J, Hu Z, Liu X, Wang J, Maletic-Savatic M, MacKenzie KR, Matzuk MM, Li F. Khalil SM, et al. Among authors: hakenjos jm. Drug Metab Dispos. 2024 Apr 24:DMD-AR-2024-001719. doi: 10.1124/dmd.124.001719. Online ahead of print. Drug Metab Dispos. 2024. PMID: 38658163 Free article.
Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1.
Holmes S, Jain P, Rodriguez KG, Williams J, Yu Z, Cerda-Smith C, Samuel ELG, Campbell J, Hakenjos JM, Monsivais D, Li F, Chamakuri S, Matzuk MM, Santini C, MacKenzie KR, Young DW. Holmes S, et al. Among authors: hakenjos jm. ACS Med Chem Lett. 2024 Jan 2;15(1):107-115. doi: 10.1021/acsmedchemlett.3c00464. eCollection 2024 Jan 11. ACS Med Chem Lett. 2024. PMID: 38229743 Free PMC article.
Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice.
Qin X, Hakenjos JM, MacKenzie KR, Barzi M, Chavan H, Nyshadham P, Wang J, Jung SY, Guner JZ, Chen S, Guo L, Krishnamurthy P, Bissig KD, Palmer S, Matzuk MM, Li F. Qin X, et al. Among authors: hakenjos jm. Drug Metab Dispos. 2022 Feb;50(2):128-139. doi: 10.1124/dmd.121.000633. Epub 2021 Nov 16. Drug Metab Dispos. 2022. PMID: 34785568 Free PMC article.
The Influence of Pain and Analgesia in Rodent Models of Sepsis.
Carpenter KC, Hakenjos JM, Fry CD, Nemzek JA. Carpenter KC, et al. Among authors: hakenjos jm. Comp Med. 2019 Dec 1;69(6):546-554. doi: 10.30802/AALAS-CM-19-000004. Epub 2019 Jun 18. Comp Med. 2019. PMID: 31213216 Free PMC article. Review.