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PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury.
Wagner J, Park LM, Mukhopadhyay P, Matyas C, Trojnar E, Damadzic R, Jung J, Bell AS, Mavromatis LA, Hamandi AM, Rosoff DB, Vendruscolo LF, Koob GF, Pacher P, Lohoff FW. Wagner J, et al. Among authors: lohoff fw. Brain Behav Immun. 2024 Apr 22;119:494-506. doi: 10.1016/j.bbi.2024.04.022. Online ahead of print. Brain Behav Immun. 2024. PMID: 38657842 Free article.
PCSK9 Base Editing Therapeutics and Ischemic Stroke.
Wagner J, Bell AS, Lohoff FW. Wagner J, et al. Among authors: lohoff fw. ACS Chem Neurosci. 2022 Dec 7;13(23):3210-3212. doi: 10.1021/acschemneuro.2c00663. Epub 2022 Nov 14. ACS Chem Neurosci. 2022. PMID: 36374568
PCSK9, A Promising Novel Target for Age-Related Cardiovascular Dysfunction.
Matyas C, Trojnar E, Zhao S, Arif M, Mukhopadhyay P, Kovacs A, Fabian A, Tokodi M, Bagyura Z, Merkely B, Kohidai L, Lajko E, Takacs A, He Y, Gao B, Paloczi J, Lohoff FW, Haskó G, Ding WX, Pacher P. Matyas C, et al. Among authors: lohoff fw. JACC Basic Transl Sci. 2023 Sep 13;8(10):1334-1353. doi: 10.1016/j.jacbts.2023.06.005. eCollection 2023 Oct. JACC Basic Transl Sci. 2023. PMID: 38094682 Free PMC article.
Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder.
Zillich L, Cetin M, Hummel EM, Poisel E, Fries GR, Frank J, Streit F, Foo JC, Sirignano L, Friske MM, Lenz B, Hoffmann S, Adorjan K, Kiefer F, Bakalkin G, Hansson AC, Lohoff FW, Kärkkäinen O, Kok E, Karhunen PJ, Sutherland GT, Walss-Bass C, Spanagel R, Rietschel M, Moser DA, Witt SH. Zillich L, et al. Among authors: lohoff fw. Alcohol Clin Exp Res (Hoboken). 2024 Feb;48(2):250-259. doi: 10.1111/acer.15241. Epub 2024 Jan 26. Alcohol Clin Exp Res (Hoboken). 2024. PMID: 38276909
Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study.
Rosoff DB, Bell AS, Mavromatis LA, Hamandi A, Park L, Jung J, Wagner J, Pacher P, Ray D, Davey Smith G, Lohoff FW. Rosoff DB, et al. Among authors: lohoff fw. Circ Genom Precis Med. 2024 Feb;17(1):e004224. doi: 10.1161/CIRCGEN.122.004224. Epub 2024 Jan 23. Circ Genom Precis Med. 2024. PMID: 38258565 No abstract available.
149 results