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Leveraging QSP Models for MIPD: A Case Study for Warfarin/INR.
Falkenhagen U, Cavallari LH, Duarte JD, Kloft C, Schmidt S, Huisinga W. Falkenhagen U, et al. Among authors: schmidt s. Clin Pharmacol Ther. 2024 Apr 24. doi: 10.1002/cpt.3274. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38655898
Genotype-guided dosing of warfarin through modeling and simulation.
Deng J, Vozmediano V, Rodriguez M, Cavallari LH, Schmidt S. Deng J, et al. Among authors: schmidt s. Eur J Pharm Sci. 2017 Nov 15;109S:S9-S14. doi: 10.1016/j.ejps.2017.05.017. Epub 2017 May 11. Eur J Pharm Sci. 2017. PMID: 28502675 Review.
A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.
Mosley SA, Kim S, El Rouby N, Lingineni K, Esteban VV, Gong Y, Chen Y, Estores D, Feng K, Kim H, Kinjo M, Langaee T, Li Z, Schmidt SOF, Johnson JA, Frye RF, Fang LL, Zhao L, Binkley PF, Schmidt S, Cavallari LH. Mosley SA, et al. Among authors: schmidt s, schmidt sof. Clin Transl Sci. 2022 Jul;15(7):1764-1775. doi: 10.1111/cts.13294. Epub 2022 May 21. Clin Transl Sci. 2022. PMID: 35488487 Free PMC article. Clinical Trial.
Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.
Thomas CD, Mosley SA, Kim S, Lingineni K, El Rouby N, Langaee TY, Gong Y, Wang D, Schmidt SO, Binkley PF, Estores DS, Feng K, Kim H, Kinjo M, Li Z, Fang L, Chapman AB, Cooper-DeHoff RM, Gums JG, Hamadeh IS, Zhao L, Schmidt S, Frye RF, Johnson JA, Cavallari LH. Thomas CD, et al. Among authors: schmidt so, schmidt s. CPT Pharmacometrics Syst Pharmacol. 2020 Dec;9(12):678-685. doi: 10.1002/psp4.12563. Epub 2020 Nov 3. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 33067866 Free PMC article. Clinical Trial.
Barriers to global pharmacometrics: educational challenges and opportunities across the globe.
Michelet R, Aulin LBS, Borghardt JM, Costa TD, Denti P, Ibarra M, Ma G, Meibohm B, Pillai GC, Schmidt S, Hennig S, Kloft C. Michelet R, et al. Among authors: schmidt s. CPT Pharmacometrics Syst Pharmacol. 2023 Jun;12(6):743-747. doi: 10.1002/psp4.12940. Epub 2023 Mar 24. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36960632 Free PMC article. No abstract available.
5,361 results