Kloft C - Search Results

1

Leveraging QSP Models for MIPD: A Case Study for Warfarin/INR.

Falkenhagen U, Cavallari LH, Duarte JD, Kloft C, Schmidt S, Huisinga W. Falkenhagen U, et al. Among authors: kloft c. Clin Pharmacol Ther. 2024 Apr 24. doi: 10.1002/cpt.3274. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38655898

2

Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia.

Henrich A, Joerger M, Kraff S, Jaehde U, Huisinga W, Kloft C, Parra-Guillen ZP. Henrich A, et al. Among authors: kloft c. J Pharmacol Exp Ther. 2017 Aug;362(2):347-358. doi: 10.1124/jpet.117.240309. Epub 2017 Jun 9. J Pharmacol Exp Ther. 2017. PMID: 28600397

3

Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach.

Mueller-Schoell A, Klopp-Schulze L, Schroth W, Mürdter T, Michelet R, Brauch H, Huisinga W, Joerger M, Neven P, Koolen SLW, Mathijssen RHJ, Copson E, Eccles D, Chen S, Chowbay B, Tfayli A, Zgheib NK, Schwab M, Kloft C. Mueller-Schoell A, et al. Among authors: kloft c. Clin Pharmacol Ther. 2020 Sep;108(3):661-670. doi: 10.1002/cpt.1960. Epub 2020 Jul 23. Clin Pharmacol Ther. 2020. PMID: 32578187

4

Time-to-Event Analysis of Paclitaxel-Associated Peripheral Neuropathy in Advanced Non-Small-Cell Lung Cancer Highlighting Key Influential Treatment/Patient Factors.

Ojara FW, Henrich A, Frances N, Huisinga W, Hartung N, Joerger M, Kloft C. Ojara FW, et al. Among authors: kloft c. J Pharmacol Exp Ther. 2020 Dec;375(3):430-438. doi: 10.1124/jpet.120.000053. Epub 2020 Oct 2. J Pharmacol Exp Ther. 2020. PMID: 33008871

5

Perspectives on Model-Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations.

Kluwe F, Michelet R, Mueller-Schoell A, Maier C, Klopp-Schulze L, van Dyk M, Mikus G, Huisinga W, Kloft C. Kluwe F, et al. Among authors: kloft c. Clin Pharmacol Ther. 2021 Jan;109(1):29-36. doi: 10.1002/cpt.2049. Epub 2020 Oct 17. Clin Pharmacol Ther. 2021. PMID: 33068303 No abstract available.

6

Quantitative relationship between infliximab exposure and inhibition of C-reactive protein synthesis to support inflammatory bowel disease management.

Grisic AM, Eser A, Huisinga W, Reinisch W, Kloft C. Grisic AM, et al. Among authors: kloft c. Br J Clin Pharmacol. 2021 May;87(5):2374-2384. doi: 10.1111/bcp.14648. Epub 2020 Dec 9. Br J Clin Pharmacol. 2021. PMID: 33184852 Free article. Clinical Trial.

7

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach.

Michelet R, Bindellini D, Melin J, Neumann U, Blankenstein O, Huisinga W, Johnson TN, Whitaker MJ, Ross R, Kloft C. Michelet R, et al. Among authors: kloft c. Front Pharmacol. 2023 Jan 12;13:1090554. doi: 10.3389/fphar.2022.1090554. eCollection 2022. Front Pharmacol. 2023. PMID: 36712688 Free PMC article.

8

Cell-level systems biology model to study inflammatory bowel diseases and their treatment options.

Stübler S, Kloft C, Huisinga W. Stübler S, et al. Among authors: kloft c. CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):690-705. doi: 10.1002/psp4.12932. Epub 2023 Feb 24. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36727252 Free PMC article.

9

Deriving mechanism-based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin.

Falkenhagen U, Knöchel J, Kloft C, Huisinga W. Falkenhagen U, et al. Among authors: kloft c. CPT Pharmacometrics Syst Pharmacol. 2023 Apr;12(4):432-443. doi: 10.1002/psp4.12903. Epub 2023 Mar 3. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36866520 Free PMC article.

10

A continued learning approach for model-informed precision dosing: Updating models in clinical practice.

Maier C, de Wiljes J, Hartung N, Kloft C, Huisinga W. Maier C, et al. Among authors: kloft c. CPT Pharmacometrics Syst Pharmacol. 2022 Feb;11(2):185-198. doi: 10.1002/psp4.12745. Epub 2021 Dec 27. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 34779144 Free PMC article.

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