Pyle AM - Search Results

1

Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy.

Wang-Bishop L, Wehbe M, Pastora LE, Yang J, Kimmel BR, Garland KM, Becker KW, Carson CS, Roth EW, Gibson-Corley KN, Ulkoski D, Krishnamurthy V, Fedorova O, Richmond A, Pyle AM, Wilson JT. Wang-Bishop L, et al. Among authors: pyle am. ACS Nano. 2024 May 7;18(18):11631-11643. doi: 10.1021/acsnano.3c06225. Epub 2024 Apr 23. ACS Nano. 2024. PMID: 38652829 Free PMC article.

2

Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists.

Jacobson ME, Becker KW, Palmer CR, Pastora LE, Fletcher RB, Collins KA, Fedorova O, Duvall CL, Pyle AM, Wilson JT. Jacobson ME, et al. Among authors: pyle am. ACS Cent Sci. 2020 Nov 25;6(11):2008-2022. doi: 10.1021/acscentsci.0c00568. Epub 2020 Oct 26. ACS Cent Sci. 2020. PMID: 33274278 Free PMC article.

3

Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway.

Palmer CR, Pastora LE, Kimmel BR, Pagendarm HM, Kwiatkowski AJ, Stone PT, Arora K, Francini N, Fedorova O, Pyle AM, Wilson JT. Palmer CR, et al. Among authors: pyle am. Adv Healthc Mater. 2024 Apr 22:e2303815. doi: 10.1002/adhm.202303815. Online ahead of print. Adv Healthc Mater. 2024. PMID: 38648653

4

Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers.

Elion DL, Jacobson ME, Hicks DJ, Rahman B, Sanchez V, Gonzales-Ericsson PI, Fedorova O, Pyle AM, Wilson JT, Cook RS. Elion DL, et al. Among authors: pyle am. Cancer Res. 2018 Nov 1;78(21):6183-6195. doi: 10.1158/0008-5472.CAN-18-0730. Epub 2018 Sep 17. Cancer Res. 2018. PMID: 30224377

5

The brace for a growing scaffold: Mss116 protein promotes RNA folding by stabilizing an early assembly intermediate.

Fedorova O, Pyle AM. Fedorova O, et al. Among authors: pyle am. J Mol Biol. 2012 Sep 21;422(3):347-65. doi: 10.1016/j.jmb.2012.05.037. Epub 2012 Jun 13. J Mol Biol. 2012. PMID: 22705286 Free PMC article.

6

Linking the group II intron catalytic domains: tertiary contacts and structural features of domain 3.

Fedorova O, Pyle AM. Fedorova O, et al. Among authors: pyle am. EMBO J. 2005 Nov 16;24(22):3906-16. doi: 10.1038/sj.emboj.7600852. Epub 2005 Oct 27. EMBO J. 2005. PMID: 16252007 Free PMC article.

7

A conserved element that stabilizes the group II intron active site.

Fedorova O, Pyle AM. Fedorova O, et al. Among authors: pyle am. RNA. 2008 Jun;14(6):1048-56. doi: 10.1261/rna.942308. Epub 2008 Apr 25. RNA. 2008. PMID: 18441048 Free PMC article.

8

Environmentally Triggerable Retinoic Acid-Inducible Gene I Agonists Using Synthetic Polymer Overhangs.

Palmer CR, Jacobson ME, Fedorova O, Pyle AM, Wilson JT. Palmer CR, et al. Among authors: pyle am. Bioconjug Chem. 2018 Mar 21;29(3):742-747. doi: 10.1021/acs.bioconjchem.7b00697. Epub 2018 Jan 19. Bioconjug Chem. 2018. PMID: 29350913 Free PMC article.

9

In Silico Discovery of Group II Intron RNA Splicing Inhibitors.

Fedorova O, Arhin G, Pyle AM, Frank AT. Fedorova O, et al. Among authors: pyle am. ACS Chem Biol. 2023 Sep 15;18(9):1968-1975. doi: 10.1021/acschembio.3c00160. Epub 2023 Aug 21. ACS Chem Biol. 2023. PMID: 37602469

10

Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses.

Jiang X, Muthusamy V, Fedorova O, Kong Y, Kim DJ, Bosenberg M, Pyle AM, Iwasaki A. Jiang X, et al. Among authors: pyle am. J Exp Med. 2019 Dec 2;216(12):2854-2868. doi: 10.1084/jem.20190801. Epub 2019 Oct 10. J Exp Med. 2019. PMID: 31601678 Free PMC article.

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