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Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites.
Dirkx L, Van Acker SI, Nicolaes Y, Cunha JLR, Ahmad R, Hendrickx R, Caljon B, Imamura H, Ebo DG, Jeffares DC, Sterckx YG, Maes L, Hendrickx S, Caljon G. Dirkx L, et al. Among authors: sterckx yg. PLoS Pathog. 2024 Apr 24;20(4):e1012181. doi: 10.1371/journal.ppat.1012181. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38656959 Free PMC article.
A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors.
Smiejkowska N, Oorts L, Van Calster K, De Vooght L, Geens R, Mattelaer H-P, Augustyns K, Strelkov SV, Lamprecht D, Temmerman K, Sterckx YG-J, Cappoen D, Cos P. Smiejkowska N, et al. Among authors: sterckx yg j. Microbiol Spectr. 2024 Mar 5;12(3):e0372323. doi: 10.1128/spectrum.03723-23. Epub 2024 Feb 5. Microbiol Spectr. 2024. PMID: 38315026 Free PMC article.
A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers.
Llauger G, Melero R, Monti D, Sycz G, Huck-Iriart C, Cerutti ML, Klinke S, Mikkelsen E, Tijman A, Arranz R, Alfonso V, Arellano SM, Goldbaum FA, Sterckx YGJ, Carazo JM, Kaufman SB, Dans PD, Del Vas M, Otero LH. Llauger G, et al. Among authors: sterckx ygj. mBio. 2023 Apr 25;14(2):e0002323. doi: 10.1128/mbio.00023-23. Epub 2023 Feb 14. mBio. 2023. PMID: 36786587 Free PMC article.
Retrospective in silico mutation profiling of SARS-CoV-2 structural proteins circulating in Uganda by July 2021: Towards refinement of COVID-19 disease vaccines, diagnostics, and therapeutics.
Odongo S, Okella H, Ndekezi C, Okee M, Namayanja M, Mujuni B, Sterckx YGJ, Kizito D, Radwanska M, Magez S, Ikwap K, Mwiine FN, Lutwama JJ, Ibingira C. Odongo S, et al. Among authors: sterckx ygj. PLoS One. 2022 Dec 22;17(12):e0279428. doi: 10.1371/journal.pone.0279428. eCollection 2022. PLoS One. 2022. PMID: 36548384 Free PMC article.
Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel Antileishmanial Compound.
Hefnawy A, Negreira G, Jara M, Cotton JA, Maes I, D'Haenens E, Imamura H, Cuypers B, Monsieurs P, Mouchtoglou C, De Winter H, Pintelon I, Timmermans JP, Berriman M, Sanders M, Martin J, de Muylder G, Dujardin JC, Sterckx YG, Domagalska MA. Hefnawy A, et al. Among authors: sterckx yg. mBio. 2022 Feb 22;13(1):e0326421. doi: 10.1128/mbio.03264-21. Epub 2022 Jan 11. mBio. 2022. PMID: 35012338 Free PMC article.
Nanobody-aided crystallization of the transcription regulator PaaR2 from Escherichia coli O157:H7.
De Bruyn P, Prolič-Kalinšek M, Vandervelde A, Malfait M, Sterckx YGJ, Sobott F, Hadži S, Pardon E, Steyaert J, Loris R. De Bruyn P, et al. Among authors: sterckx ygj. Acta Crystallogr F Struct Biol Commun. 2021 Oct 1;77(Pt 10):374-384. doi: 10.1107/S2053230X21009006. Epub 2021 Sep 21. Acta Crystallogr F Struct Biol Commun. 2021. PMID: 34605442 Free PMC article.
The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG75 as Examples.
Magez S, Li Z, Nguyen HTT, Pinto Torres JE, Van Wielendaele P, Radwanska M, Began J, Zoll S, Sterckx YG. Magez S, et al. Among authors: sterckx yg. Pathogens. 2021 Aug 19;10(8):1050. doi: 10.3390/pathogens10081050. Pathogens. 2021. PMID: 34451514 Free PMC article.
37 results