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Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol.
J Vis Exp. 2024 Apr 5;(206). doi: 10.3791/66550.
J Vis Exp. 2024.
PMID: 38647283
miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.
Nobre RJ, Lobo DD, Henriques C, Duarte SP, Lopes SM, Silva AC, Lopes MM, Mariet F, Schwarz LK, Baatje MS, Ferreira V, Vallès A, Pereira de Almeida L, Evers MM, Toonen LJA.
Nobre RJ, et al. Among authors: lobo dd.
Nucleic Acid Ther. 2022 Jun;32(3):194-205. doi: 10.1089/nat.2021.0020. Epub 2021 Dec 7.
Nucleic Acid Ther. 2022.
PMID: 34878314
Free PMC article.
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Viral-based animal models in polyglutamine disorders.
Henriques C, Lopes MM, Silva AC, Lobo DD, Badin RA, Hantraye P, Pereira de Almeida L, Nobre RJ.
Henriques C, et al. Among authors: lobo dd.
Brain. 2024 Apr 4;147(4):1166-1189. doi: 10.1093/brain/awae012.
Brain. 2024.
PMID: 38284949
Review.
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Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders.
Silva AC, Lobo DD, Martins IM, Lopes SM, Henriques C, Duarte SP, Dodart JC, Nobre RJ, Pereira de Almeida L.
Silva AC, et al. Among authors: lobo dd.
Brain. 2020 Feb 1;143(2):407-429. doi: 10.1093/brain/awz328.
Brain. 2020.
PMID: 31738395
Review.
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ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease.
Vasconcelos-Ferreira A, Martins IM, Lobo D, Pereira D, Lopes MM, Faro R, Lopes SM, Verbeek D, Schmidt T, Nóbrega C, Pereira de Almeida L.
Vasconcelos-Ferreira A, et al.
Mol Ther. 2022 Jan 5;30(1):370-387. doi: 10.1016/j.ymthe.2021.07.012. Epub 2021 Jul 21.
Mol Ther. 2022.
PMID: 34298131
Free PMC article.
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Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3.
Rufino-Ramos D, Albuquerque PR, Leandro K, Carmona V, Martins IM, Fernandes R, Henriques C, Lobo D, Faro R, Perfeito R, Mendonça LS, Pereira D, Gomes CM, Nobre RJ, Pereira de Almeida L.
Rufino-Ramos D, et al.
Mol Ther. 2023 May 3;31(5):1275-1292. doi: 10.1016/j.ymthe.2023.04.001. Epub 2023 Apr 6.
Mol Ther. 2023.
PMID: 37025062
Free PMC article.
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