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46 results

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Page 1
Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia.
Elgamal OA, Fobare S, Vibhute S, Mehmood A, Vroom DC, Johnson ML, Stearns B, Lerma JR, Truxall J, Stahl E, Carmichael B, Orwick SJ, Mims AS, Curran E, Santhanam R, Tridandapani S, Phelps MA, Xie Z, Coss CC, Baker SD, Patrick J, Ezzell JK, Rai J, Pan J, Rai SN, Stillwell C, Wunderlich M, Abdulrahim M, Goodwin TE, Hilinski G, Bennett CE, Hertlein E, Byrd JC. Elgamal OA, et al. Among authors: hertlein e. JCI Insight. 2024 Apr 22;9(8):e173646. doi: 10.1172/jci.insight.173646. JCI Insight. 2024. PMID: 38646934 Free PMC article.
TP-0903 is active in models of drug-resistant acute myeloid leukemia.
Jeon JY, Buelow DR, Garrison DA, Niu M, Eisenmann ED, Huang KM, Zavorka Thomas ME, Weber RH, Whatcott CJ, Warner SL, Orwick SJ, Carmichael B, Stahl E, Brinton LT, Lapalombella R, Blachly JS, Hertlein E, Byrd JC, Bhatnagar B, Baker SD. Jeon JY, et al. Among authors: hertlein e. JCI Insight. 2020 Dec 3;5(23):e140169. doi: 10.1172/jci.insight.140169. JCI Insight. 2020. PMID: 33268594 Free PMC article.
Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia.
Elgamal OA, Mehmood A, Jeon JY, Carmichael B, Lehman A, Orwick SJ, Truxall J, Goettl VM, Wasmuth R, Tran M, Mitchell S, Lapalombella R, Eathiraj S, Schwartz B, Stegmaier K, Baker SD, Hertlein E, Byrd JC. Elgamal OA, et al. Among authors: hertlein e. J Hematol Oncol. 2020 Jan 28;13(1):8. doi: 10.1186/s13045-019-0821-7. J Hematol Oncol. 2020. PMID: 31992353 Free PMC article.
Inhibition of Enhancer of Zeste Homolog 2 Induces Blast Differentiation, Impairs Engraftment and Prolongs Survival in Murine Models of Acute Myeloid Leukemia.
Fobare S, Elgamal OA, Wunderlich M, Stahl E, Mehmood A, Furby C, Lerma JR, Sesterhenn TM, Pan J, Rai J, Johnstone ME, Abdul-Aziz A, Johnson ML, Rai SN, Byrd JC, Hertlein E. Fobare S, et al. Among authors: hertlein e. Cancers (Basel). 2024 Jan 29;16(3):569. doi: 10.3390/cancers16030569. Cancers (Basel). 2024. PMID: 38339323 Free PMC article.
CLL and activated NF-kappaB: living partnership.
Hertlein E, Byrd JC. Hertlein E, et al. Blood. 2008 May 1;111(9):4427. doi: 10.1182/blood-2008-02-137802. Blood. 2008. PMID: 18441243 Free article. No abstract available.
HLA-DR meets ERK.
Hertlein E, Byrd JC. Hertlein E, et al. Blood. 2010 Jun 24;115(25):5126-7. doi: 10.1182/blood-2010-03-270256. Blood. 2010. PMID: 20576816 Free article. No abstract available.
Signalling to drug resistance in CLL.
Hertlein E, Byrd JC. Hertlein E, et al. Best Pract Res Clin Haematol. 2010 Mar;23(1):121-31. doi: 10.1016/j.beha.2010.01.007. Best Pract Res Clin Haematol. 2010. PMID: 20620976 Review.
Molecular, clinical, and prognostic implications of PTPN11 mutations in acute myeloid leukemia.
Fobare S, Kohlschmidt J, Ozer HG, Mrózek K, Nicolet D, Mims AS, Garzon R, Blachly JS, Orwick S, Carroll AJ, Stone RM, Wang ES, Kolitz JE, Powell BL, Oakes CC, Eisfeld AK, Hertlein E, Byrd JC. Fobare S, et al. Among authors: hertlein e. Blood Adv. 2022 Mar 8;6(5):1371-1380. doi: 10.1182/bloodadvances.2021006242. Blood Adv. 2022. PMID: 34847232 Free PMC article.
Framework of clonal mutations concurrent with WT1 mutations in adults with acute myeloid leukemia: Alliance for Clinical Trials in Oncology study.
Bhatnagar B, Kohlschmidt J, Orwick SJ, Buelow DR, Fobare S, Oakes CC, Kolitz JE, Uy G, Stock W, Powell BL, Nicolet D, Hertlein EK, Mrózek K, Blachly JS, Eisfeld AK, Baker SD, Byrd JC. Bhatnagar B, et al. Among authors: hertlein ek. Blood Adv. 2023 Aug 22;7(16):4671-4675. doi: 10.1182/bloodadvances.2023010482. Blood Adv. 2023. PMID: 37603350 Free PMC article. No abstract available.
46 results