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PGC-1α drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity.
Varuzhanyan G, Chen CC, Freeland J, He T, Tran W, Song K, Wang L, Cheng D, Xu S, Dibernardo GA, Esedebe FN, Abt ER, Park JW, Memarzadeh S, Graeber T, Shirihai O, Witte O. Varuzhanyan G, et al. Among authors: graeber t. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588489. doi: 10.1101/2024.04.09.588489. bioRxiv. 2024. PMID: 38645232 Free PMC article. Preprint.
MITF regulates IDH1 and NNT and drives a transcriptional program protecting cutaneous melanoma from reactive oxygen species.
Roider E, Lakatos AIT, McConnell AM, Wang P, Mueller A, Kawakami A, Tsoi J, Szabolcs BL, Ascsillán AA, Suita Y, Igras V, Lo JA, Hsiao JJ, Lapides R, Pál DMP, Lengyel AS, Navarini A, Okazaki A, Iliopoulos O, Németh I, Graeber TG, Zon L, Giese RW, Kemeny LV, Fisher DE. Roider E, et al. Among authors: graeber tg. bioRxiv [Preprint]. 2023 Nov 14:2023.11.10.564582. doi: 10.1101/2023.11.10.564582. bioRxiv. 2023. PMID: 38014031 Free PMC article. Preprint.
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. Knight DA, et al. Among authors: graeber tg. J Clin Invest. 2023 Dec 15;133(24):e177489. doi: 10.1172/JCI177489. J Clin Invest. 2023. PMID: 38099495 Free PMC article. No abstract available.
Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation.
Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, Noguchi M, Mao Z, Morrissey C, Corey E, Nelson PS, Zhao Y, Huang J, Park JW, Witte ON, Graeber TG. Chen CC, et al. Among authors: graeber tg. Cancer Cell. 2023 Dec 11;41(12):2066-2082.e9. doi: 10.1016/j.ccell.2023.10.009. Epub 2023 Nov 22. Cancer Cell. 2023. PMID: 37995683 Free article.
A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.
Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A. Palermo A, et al. Among authors: graeber tg. Commun Biol. 2023 Nov 3;6(1):1115. doi: 10.1038/s42003-023-05478-7. Commun Biol. 2023. PMID: 37923961 Free PMC article.
Fibroblast Activation Protein Expression in Sarcomas.
Crane JN, Graham DS, Mona CE, Nelson SD, Samiei A, Dawson DW, Dry SM, Masri MG, Crompton JG, Benz MR, Czernin J, Eilber FC, Graeber TG, Calais J, Federman NC. Crane JN, et al. Among authors: graeber tg. Sarcoma. 2023 Jun 9;2023:2480493. doi: 10.1155/2023/2480493. eCollection 2023. Sarcoma. 2023. PMID: 37333052 Free PMC article.
CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis.
Minami JK, Morrow D, Bayley NA, Fernandez EG, Salinas JJ, Tse C, Zhu H, Su B, Plawat R, Jones A, Sammarco A, Liau LM, Graeber TG, Williams KJ, Cloughesy TF, Dixon SJ, Bensinger SJ, Nathanson DA. Minami JK, et al. Among authors: graeber tg. Cancer Cell. 2023 Jun 12;41(6):1048-1060.e9. doi: 10.1016/j.ccell.2023.05.001. Epub 2023 May 25. Cancer Cell. 2023. PMID: 37236196 Free article.
Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma.
Hu J, Tan P, Ishihara M, Bayley NA, Schokrpur S, Reynoso JG, Zhang Y, Lim RJ, Dumitras C, Yang L, Dubinett SM, Jat PS, Van Snick J, Huang J, Chin AI, Prins RM, Graeber TG, Xu H, Wu L. Hu J, et al. Among authors: graeber tg. Signal Transduct Target Ther. 2023 Apr 17;8(1):155. doi: 10.1038/s41392-023-01362-2. Signal Transduct Target Ther. 2023. PMID: 37069149 Free PMC article.
152 results